the unrecognised revolution in global health
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The Unrecognised Revolution in Global Health An update on the state of the neglected disease R&D product pipeline Dr Nick Chapman Director of Research, Policy Cures Berlin, 13 October 2015 Current state of the neglected disease R&D


  1. The Unrecognised Revolution in Global Health An update on the state of the neglected disease R&D product pipeline Dr Nick Chapman Director of Research, Policy Cures Berlin, 13 October 2015

  2. Current state of the neglected disease R&D pipeline The R&D pipeline for neglected diseases is healthier now than it has ever been 485 485 365 215? product candidates in the pipeline 2004 2012 2015

  3. Current state of the neglected disease R&D pipeline It is largely being driven by public health goals 80% of all candidates have a public sector partner

  4. Current state of the neglected disease R&D pipeline PDPs are involved in the development of: 40% of all pipeline candidates 68% of all public-private partnered candidates This is despite the fact that PDPs received only 15% of total funding for neglected disease R&D in 2013

  5. Current state of the neglected disease R&D pipeline Industry is playing a critical role 59% of all candidates in the pipeline have an industry partner … mostly in partnership with the public sector Two thirds of all industry involvement is in partnership with the public sector

  6. Current state of the neglected disease R&D pipeline It is highly concentrated on just three diseases (malaria, TB, and HIV/AIDS) Kinetoplastids All other diseases combined Tuberculosis Helminth Malaria HIV/AIDS infections Diarrhoeal Hepatitis C diseases 67%

  7. What does this mean? The current model is working … and this needs both recognition and support

  8. What does this mean? That is not to say that there is not room for improvement • Better funding • Better prioritisation

  9. What does this mean? With sustained, appropriate support, we will see the delivery of many exciting transformative technologies over the next 15 years

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