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Event Horizon Telescope, 2019
Lenses Beyond Limits Jen Dionne, Stanford University Event Horizon - - PowerPoint PPT Presentation
Lenses Beyond Limits Jen Dionne, Stanford University Event Horizon - - PowerPoint PPT Presentation
Lenses Beyond Limits Jen Dionne, Stanford University Event Horizon Telescope, 2019 Earthrise, William Anders, NASA Co Rentmeester, 1984 Wilhelm Rontgen, 1985 The Inner Life of a Cell, XVIVO, Cellular Visions and Harvard Tarun Narayan, Andrea
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Earthrise, William Anders, NASA
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Co Rentmeester, 1984
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Wilhelm Rontgen, 1985
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The Inner Life of a Cell, XVIVO, Cellular Visions and Harvard
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Tarun Narayan, Andrea Baldi, and Fariah Hayee
40
Narayan*, Hayee*, Baldi, Koh, Sinclair, Dionne, Nature Comm. (2017)
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Ashwin Atre
50 nm
Atre, Brenny, Coenen, Garcia-Etxarri, Polman, Dionne, Nature Nanotechnology (2015)
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1 Force (μN) 10
Lay, Goodman, Dionne, Submitted (2019)
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amino acid Sugar mirror plane DNA
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limonene
DNA
thalidomide Treats morning nausea Induces birth defects
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Approximately 50% of drugs and 40% of agrochemicals are chiral Of these, more than 90% are sold as mixtures of both enantiomers
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Can we use light to separate enantiomers?
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E B time
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Circularly polarized light chiral nanospecimen nanocoaxial
- ptical fiber
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R-enantiomer L-enantiomer
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Right circularly polarized light
L-enantiomer R-enantiomer
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Yang Zhao and Amr Saleh
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2.5 Pulling force (pN)
Right circularly polarized light, 5 nanometer R-enantiomer
Y Zhao & J. Dionne et al. ACS Photonics (2016)
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2.5 Pulling force (pN)
Right circularly polarized light, 5 nanometer R-enantiomer
Y Zhao & J. Dionne et al. ACS Photonics (2016)
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2.5 Pulling force (pN)
Left circularly polarized light, 5 nanometer R-enantiomer
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2.5 Pulling force (pN)
Left circularly polarized light, 5 nanometer R-enantiomer
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1µm
5 µm
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Force (pN/100µW/µm
2)
λ=770 nm 10
T
15 Time (s)
ime ) pN
- rce (
ulling F P
60 Laser On
Light
- n
40 20 Off
Light off
5 20
- Y. Zhao, A. Saleh, J. Dionne, et al., Nature Nanotechnology (2017)
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R-isomer L-isomer
Force (pN) 6
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80 RCP
4
LCP
L-isomer
1
Force (pN/100µW/µm2)
Lateral Force (pN)
75
- 6
R-isomer
Enantiomeric Excess (%)
No filter With filter
70 40 60 80 100
Tip-aperture separation (nm) 40 100 Yield (%) 100
z (nm)
- Y. Zhao, A. Saleh, J. Dionne, et al., Nature Nanotechnology (2017)
- M. Solomon, J. Hu, J. Dionne, et al. ACS Photonics (2019)
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