Intra-operative nuclear imaging Using navigated gamma-probes for - PowerPoint PPT Presentation

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Intra-operative nuclear imaging Using navigated gamma-probes for tumor localization Wendler, T.; Traub, J.; Hartl, A.; Daghighian, F.*; Ziegler, S.I.; Navab, N. * IntraMedical Imaging LLC, Los Angeles 03 July 2007 Chair for Computer Aided Medical Procedures Department of Computer Science | TU Munich Department of Nuclear Medicine Klinikum rechts der Isar | TU Munich

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Background • For years Nuclear Medicine has been used for surgical planning in cancer resection. • However, given the high-energy nature of most cancer tracers, intra-operative assistance devices have been limited to high-energy γ - probes and β -probes 1 . • The combination of β -probes with navigation has shown to offer novel intuitive approaches to radio-guided surgery 2 . 1 E.g. Essner et al. 2002, Meller et al. 2005, Piert et al. 2007… 2 Wendler et al. 2006, Kishenkov et al. 2007

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Objectives • Evaluate the possibilities of using γ -probes combined with navigation. • Development of a system capable of intra- operative tomographic reconstruction.

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Objectives ??? ...

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Materials ART2 Cameras γ -probe & & DTrack, NodeSeeker, ART GmbH IntraMedical Imaging LLC Biograph Sensation 16 PET/CT, Siemens Multi-well phantom 0.1, 0.2 and 0.5 MBq F-18

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Methods Phantom preparation Navigated γ -probe scan PET/CT scan System matrix calculation Reconstruction Rigid registration Comparison

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Methods ... 2-3 min

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Results 12 cm 8 cm Reconstructed Corresponding Ground truth image PET slice (real activity)

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Conclusion • 2D reconstruction using γ -probes is possible. • These preliminary results introduce a promising new alternative toward intra-operative 3D functional imaging.

Intra-operative nuclear imaging Using navigated gamma-probes for - PowerPoint PPT Presentation

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Intra-operative nuclear imaging Using navigated gamma-probes for tumor localization Wendler, T.; Traub, J.;

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Intra-operative nuclear imaging Using navigated gamma-probes for - PowerPoint PPT Presentation

chair for computer aided medical procedures (CAMP) | campar.in.tum.de department of nuclear medicine (MRI|NM) | www.nuk.med.tum.de Intra-operative nuclear imaging Using navigated gamma-probes for tumor localization Wendler, T.; Traub, J.;

Optimization of Acquisition Geometry for Intra-operative Tomographic Imaging J. Vogel T. Reichl

Nuclear Imaging Medical Imaging Medical Imaging Nuclear Imaging Nuclear Imaging Nuclear

Registration-Free Laparoscope Augmentation for Intra-Operative Liver Resection Planning Marco

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CDP for real-time intra-operative margin detection in Breast Cancer (Electrotechnical Surgery)

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Imaging and Therapy in Nuclear Medicine Jan de Swart PET and SPECT Ultra high sensitivity

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to Neuroradiology Brain Imaging The basic imaging tools Fluoroscopy/Radiography Computed

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Imaging of the fetus John A. Cassese M.D. Assistant Professor Departments of Diagnostic Imaging

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