Radiation in Medicine: Roles of Physicists Ping Xia, Ph.D. - - PowerPoint PPT Presentation

radiation in medicine roles of physicists
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Radiation in Medicine: Roles of Physicists Ping Xia, Ph.D. - - PowerPoint PPT Presentation

Radiation in Medicine: Roles of Physicists Ping Xia, Ph.D. Professor in Medicine Head of Medical Physics in Radiation Oncology Cleveland Clinic, Cleveland, OH, USA Who Are Medical Physicists? Have an MS or Ph.D. in medical physics,


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Radiation in Medicine: Roles of Physicists

Ping Xia, Ph.D. Professor in Medicine Head of Medical Physics in Radiation Oncology Cleveland Clinic, Cleveland, OH, USA

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Who Are Medical Physicists?

  • Have an MS or Ph.D. in medical physics, physics, or a

related discipline

  • Have training in clinical medical physics in four sub-

specialties:

70% 15% 5% 10% Therapeutic (cancer treatment) Diagnostic (imaging) Nuclear Medicine (imaging) Public Health

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What Do Medical Physicists Do?

Teaching Research Clinical Service

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Clinical Services

–Treatment planning design for radiation treatment of cancer patients –Quality assurance (QA) of radiation

  • utputs

–Quality control in imaging systems –Monitor radiation exposure to patients and employees

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Treatment Planning Design

  • Using CT images as a

patient model

  • Design the best radiation

beam directions and intensities

  • Based on the tumor

location and prescription dose.

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An Example of Radiation Dose Distributions

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A1 A3 A2 A4 A5

Detectors --> A1 A2 A3* A4 A5 B1 B2 B3 B4 RTP-dose 81.7 82.0 99.4 96.8 82.0 102.6 101.9 91.5 90.2 MOSFET 81 82 97 99 82 102 102 94 93 %DIV

  • 0.9%

0.0%

  • 2.4%
  • 2.3%

0.0%

  • 0.6%

0.0% 2.7% 3.1%

Point doses : RTP vs MOSFET (cGy)

Patient Specific QA

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How Research Improves Clinical Care

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Conventional Dose Distributions

49 Gy 45 Gy 35 Gy

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59.0 Gy 54.0 Gy 48.6 Gy 45.0 Gy 35.0 Gy

A Typical Modern Plan

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Computer Optimization in Treatment Planning

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Intensity Modulated Volumetric Arc Therapy

Increased beam directions from 7~9 to 90~180

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Image Guided Radiation Delivery

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On Board Imager (OBI)– KV-Cone Beam CT

Elekta KV-OBI Varian KV-OBI

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CT on Rails

Siemens

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Co-Registration Between Image of the day With Initial CT Images

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On the Horizon

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Depth-dose curve for 177 MeV protons

5 10 15 20 25 1 2 3

Depth in water (cm) Dose per proton (nGy)

2

c) ( 1 β ∝ dX dE

Width of peak dependent on range straggling in medium and initial energy spectrum; typically 8 mm for 177 MeV p Peak-to-plateau ratio 3-5 (depending on width of energy spectrum)

Promise of Proton Radiotherapy

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10 Gy 20 Gy 35 Gy 50 Gy 70 Gy

Current Photon Therapy Current Proton Therapy Future Image-Guided Proton Therapy

Research Driven Patient Care

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Summary

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Radiation Therapy Is Effective

  • Radiation therapy is a local treatment.
  • Radiation is a universal treatment that can

treat most solid tumors effectively.

  • About 50% of all cancer patients receive

some type of radiation therapy sometime during the course of their treatment.

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Responsibilities Of A Medical Physicist

  • Assure the safe and effective delivery of

radiation

  • A qualified medical physicist

– Obtains a MS or Ph.D. degree – Receives clinical training and passes a specific board exam.