with BRCA mutations in Montreal Najlaa Houssaini 1 , Christine - PowerPoint PPT Presentation

Feb 22, 2024 •514 likes •560 views

Case-control study of nutrition and lifestyle among breast cancer women with BRCA mutations in Montreal Najlaa Houssaini 1 , Christine Maugard 3 , Steven Narod 3 , Andr Robidoux 2 , Parviz Ghadirian 4 McGill University 1 , Medicine, Research

Case-control study of nutrition and lifestyle among breast cancer women with BRCA mutations in Montreal Najlaa Houssaini 1 , Christine Maugard 3 , Steven Narod 3 , André Robidoux 2 , Parviz Ghadirian 4 McGill University 1 , Medicine, Research Centre (CHUM) 2 , Montreal, Familial Breast Cancer Research Unit 3 , Women's College Hospital Research Institute, Toronto, Medicine, Université de Montréal, Montréal, Canada 4
Objectives • The possible role of nutrition and lifestyle in the etiology of breast cancer among French Canadian women with BRCA mutations. Methods • Nested case-control study • 44 women with breast cancer compared with 44 women with no breast cancer.
Risk factors • Education OR = 7.82, 95% CI :( 1.99-30.69) • High intake of monounsaturated fatty acid OR = 6.00 Protective factors • Breast feeding OR = 0.35 95% CI = (0.12-1.06) • Moderate physical activity OR = 0,28 - 95% IC (0.08-0.95) • High intake of fruits OR = 0.27; 95% CI :(0.07-1.01) • Vitamine K OR = 0.17, 95% (0.05-0.61) Conclusion Although the sample size of this case-control study was small, we were able to detect certain risk factors among BRCA mutation carriers.

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