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http://www.broadinstitute.org/cancer/cga/mutsig
MutSig http://www.broadinstitute.org/cancer/cga/mutsig Covered - - PowerPoint PPT Presentation
MutSig http://www.broadinstitute.org/cancer/cga/mutsig Covered - - PowerPoint PPT Presentation
MutSig http://www.broadinstitute.org/cancer/cga/mutsig Covered Bases/Total Possible Mutations for that Gene & Category Score # Observed Background for that mutations in Mutation Rate gene Sum over each that gene & mutation
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Score for that gene Sum over each mutation category Background Mutation Rate # Observed mutations in that gene & category Covered Bases/Total Possible Mutations for that Gene & Category
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+
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Covariate 1 (Z Score) Covariate 2 (Z Score)
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Lawrence et al. Nature, Jan 2014.
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