Using International Information In National Single Step Genomic BLUP - PowerPoint PPT Presentation

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Using International Information In National Single Step Genomic BLUP In Swiss Dairy Cattle Christian Stricker and Peter von Rohr 2018-06-06 Current Situation In Swiss dairy cattle breeding, genomic breeding values are estimated using

Using International Information In National Single Step Genomic BLUP In Swiss Dairy Cattle Christian Stricker and Peter von Rohr 2018-06-06
Current Situation In Swiss dairy cattle breeding, genomic breeding values are estimated using ◮ marker-effect models (MEM) ◮ Bayesian regression approach (Bayes A − C and C π ) ◮ two-step procedure
Two-Step
Information Exchange In dairy breeds with gene-flow from foreign countries ◮ Exchange of genotypes ◮ Phenotypes not exchanged → MEM evaluations based on de-regressed MACE breeding values
Single Step GBLUP ◮ In general BLUP is widely accepted in animal breeding ◮ Genomic BLUP (GBLUP) can be parametrized as MEM and as breeding-value model (BVM) ◮ In BVM the sum of SNP-effects is modelled as random component u ◮ Legarra et al. (2009) and Christensen and Lund (2010) showed single-step GBLUP approach
Comparison
Combining Information Sources
Proposed Approach
The End ◮ Website: https://charlotte-ngs.github.io/SingleStepGBLUP/ ◮ Questions? ◮ Thank you for your attention

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