The 16 th U.S.-Korea Forum on Nanotechnology nanshulu@utexas.edu - - PowerPoint PPT Presentation
The 16 th U.S.-Korea Forum on Nanotechnology nanshulu@utexas.edu - - PowerPoint PPT Presentation
The 16 th U.S.-Korea Forum on Nanotechnology nanshulu@utexas.edu Bioelectronics Closing the Loop for Internet of Health (IoH) Data Analytics Medical diagnosis Signal Processing Prof. Dae-Hyeong Kim Seoul National Univ. Biomarker
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Bioelectronics – Closing the Loop for Internet of Health (IoH)
Choi, Kim*, et al., Adv. Mater. 28, 4203 (2016).
Biomarker Sensing Medical diagnosis Signal Processing Data Analytics Mobile/Home Treatment
- Prof. Dae-Hyeong Kim
Seoul National Univ.
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HUMAN-ROBOT INTERFACE MOBILE HEALTH & PERSONALIZED MEDICINE PROSTHESIS BRAIN-COMPUTER INTERFACE REHABILITATION
Example Applications of Wearable Electronics
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ESi = 130 GPa, efrac = 1% ESkin = 130 kPa, eouch = 20%
Credit: Intel Credit: ICTGraphicsLab @ USC
Silicon vs. Skin – A Mechanical Challenge
Freeform Manufacture
- Adv. Mater. 27, 6423-6430 (2015)
EML 2, 37-45 (2015) ACS Nano 11, 7634–7641 (2017)
- Adv. Mater. Tech. 1800600 (2019)
- Adv. Mater. Tech. 1900117 (2019)
Bio-Electronics Interface
JMR 30, 2702-2712 (2015)
- Adv. Healthc. Mater. 5, 80-87 (2015)
JAM 83, 041007 (2016) Soft Robotics 3, 99-100 (2016)
- Adv. Funct. Mater. 26, 3207-3217 (2016)
JAM 84, 111003 (2017) EML 15, 130 (2017)
- J. Roy. Soc. Interface 14, 20170377 (2017)
Soft Matter 14, 8509 (2018) EML 30, 100496 (2019)
E-Tattoo
Skin
Soft Bioelectronics
Nature Nanotech. 9, 397–404 (2014)
- Adv. Mater. 27, 6423-6430 (2015)
ACS Nano 9, 5937-5946 (2015) Nature Nanotech. 11, 566-572 (2016)
- Sci. Transl. Med. 8, 86 (2016)
ACS Nano 11, 7634–7641 (2017) Nature Comm. 8,1664 (2017) npj Flexible Electronics 2, 6 (2018) Sensors 18, 1269 (2018) Micromachines 9, 170 (2018)
- Adv. Funct. Mater. 1808247 (2019)
- Adv. Mater. Tech. 1900117 (2019)
- Adv. Sci. 1900290 (2019)
NPG Asia Materials 11, 43 (2019)
Lu Research Group
2D Materials & Devices
- Adv. Mater. Interface 2, 1500176 (2015)
Nano Lett. 15, 1883–1890 (2015) Nature Nanotech. 11, 566-572 (2016) EML 13, 42-77 (2017) ACS Nano 11, 7634–7641 (2017) Nano Lett. 17, 5464 (2017) npj 2D Materials and Applications 2, 19 (2018) PNAS 115, 7884 (2018) PRL 121, 266101 (2018) Nature 567, 71 (2019) 2D Materials, accepted (2019) JMPS, revision submitted (2019)
Mechanics of Flexible and Stretchable Structures
Sensors 13, 8577-8594 (2013) IJSS 51, 4026-4037 (2014) IJF 190, 99 (2014)
- Nat. Photonics 8, 643–649 (2014)
ACS Nano 8, 12265–12271 (2014) EML 2, 37-45 (2015)
- Curr. Opin. Solid St. M. 19, 149-159 (2015)
IJSS 87, 48-60 (2016) Smart Mater. Struct. 25, 035037 (2016) JAM 84, 021004 (2017) Light 7, e17138 (2018) JAM 86, 051010 (2019)
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emax
2%
Serpentine Ribbons – 2D Springs
Stretchability and compliance can be achieved by serpentine structures of ANY material. eapp = 114%
Widlund, Yang, Hsu, Lu*, IJSS 51, 4026 (2014). Yang, Lu*, et al, IJF 190, 99 (2014). Yang, Lu*, et al, EML 2, 37 (2015). Yang, Qiao, Lu*, JAM 84, 021004 (2016). Liu, Ha, Lu*, JAM 86, 051010 (2019)
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Kim†, Lu†, Ma† (†equal contribution), Rogers*, et al., Science 333, 838, (2011).
Ultrathin, ultrasoft, noninvasive, stretchable and multifunctional
Strain (%) 5 10 15 20 25 30 Stress (kPa) 30 60 90 skin: 160 kPa y: 150 kPa x: 130 kPa FEM x FEM y
Ecoflex 0.5mm EP sensor
x y
Au Ecoflex PI 30µm 0.5µm
Neck Wrist
Time (sec) 1 2 3 Amplitude (V)
- 800
- 400
400
- 30
30 60 Time (sec) 1 2 3
- 800
- 400
400 Amplitude (V)
- 30
30 60 Time (sec) 1 2 3 Amplitude (V)
- 800
- 400
400 Amplitude (V)
- 20
20 40 60
up down left
Time (sec) 1 2 3
- 800
- 400
400 Amplitude (V)
- 30
30 60
right up right left down
Epidermal Electronics (E-Tattoos)
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8 Fully-Conformal Non-Conformal Partially conformal
Skin
Conventional E-Tattoo
Skin Skin
Jeong, Rogers* et. al., Adv. Mater. 25, 6839 (2013).
Conformable contact ensures
- Low interface impedance higher signal to noise ratio
- No slippage less motion artifacts, more accurate
measurement of skin deformation
- Better heat or mass transfer across the skin-tattoo interface
𝝁 = 𝟑𝟔𝟏 𝛎𝐧 𝒊𝟏 = 𝟔𝟏 𝛎𝐧 ഥ 𝑭𝒕 = ഥ 𝑭𝒏= 𝟘𝟑 𝐥𝐐𝐛 𝜹 = 𝟔𝟏 𝐧𝐊/𝐧𝟑
Conformability
𝒖 = 𝟔 𝛎𝐧 𝒖 = 𝟒𝟕 𝛎𝐧 𝒖 = 𝟐𝟏𝟏 𝛎𝐧
𝜽 𝒖 (𝛎𝐧)
Wang, Lu*, JAM 83, 041007 (2016).
Ecoflex on skin
Ultra-Soft & Ultra-Thin Ultimate Conformability
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Electronically functional Atomically thin (nm) Optically transparent Mechanically robust (cuttable) Chemically inert Potentially low cost
World’s Thinnest Materials – 2D Materials
Jang, Lu*, et al., npj 2D Materials and Applications (invited review), in preparation (2019).
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Wet transfer Dry patterning
Ameri, Akinwande*, Lu*, et al., ACS Nano 11, 7634 (2017).
- Prof. Deji Akinwande
UT-Austin ECE
Cut-and-Paste Manufacture of Graphene E-Tattoo Sensors (GETS)
- Dr. Shideh K. Ameri
UT-Austin ECE (Queen’s University, Canada)
ECCS-1541684
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GETS Characterization
GETS
Serpentine
Ameri, Akinwande*, Lu*, et al., ACS Nano 11, 7634 (2017).
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Stretchability of Graphene/PMMA
2 4 6 8 10 12 14 16 18 20 10 20 30 40 50 60 70
R/R0 Applied Strain (%)
100 nm Au on 300-nm PMMA Monolayer graphene
- n 300-nm PMMA
Straight ribbons
Jang, Lu*, et al., 2D Materials, accepted (2019).
Double-sided tape (DST) Tegaderm Au/PET Connector
Cross-Section
DST Tegaderm PMMA Au PET Gr
ɛ
Stage I
(0-0.9%)
Stage II
(0.9-2.5%)
Stage III
(2.5-8%)
Stage IV
(8%-Break)
GB
Micro- crack (Graphene)
ɛ
Macro- crack (PMMA)
ɛ ɛ
Defect
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500-nm thick
Ameri, Akinwande*, Lu*, et al., ACS Nano 11, 7634 (2017).
GETS Are Fully Conformable to the Skin
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GETS Are as Deformable as Skin
Ameri, Akinwande*, Lu*, et al., ACS Nano 11, 7634 (2017).
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Multifunctional GETS
Ameri, Akinwande*, Lu*, et al., ACS Nano 11, 7634 (2017).
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Right (-) Ground Left (+) Up (+) Down (-) Right-Left Channel Up-Down Channel
Normal Sour-face Laugh Frown
Transparent GETS for Electrooculogram (EOG)
Ameri, Akinwande*, Lu*, et al., npj 2D Materials and Applications 2, 19 (2018).
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Imperceptible Human Robot Interface (HRI) by GETS
Ameri, Akinwande*, Lu*, et al., npj 2D Materials and Applications 2, 19 (2018).
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18 Lee, Lu, Kim*, et al., Nat. Nanotech. 11, 566-572 (2016).
- Prof. Dae-Hyeong Kim
Seoul National Univ.
Graphene-Based E-Tattoo for Diabetics
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Going Wireless – Near Field vs. Far Field Technology
Near Field (Induction) Far Field (Radiation)
Advantage Disadvantage Advantage Disadvantage
- Less power
consumption
- Passive mode
without battery
- Data transfer rate
: 424 kpbs
- Operating range
: ~10 cm
- Data transfer rate
: 3 Mbps
- Operating range
: ~10 m
- Battery powered
DOMINANT TERMS IN THE REGION (Power density attenuation)
𝒔 : distance
1 𝑠6 1 𝑠2
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“Cut-Solder-Paste” Method for Integrating ICs on E-Tattoos
Cu foil Thermal Release Tape Water Soluble Tape Kapton Tape Water Tegaderm
a b d h g e c Soldering f Water Pasting Cutting
Jeong, Lu*, et al., Adv. Mater. Tech. 1900117 (2019).
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Robustness of Wireless E-Tattoos
Jeong, Lu*, et al., Adv. Mater. Tech. 1900117 (2019).
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Assembly and Disassembly up to 20 times
A B C D Peeling off Peeled off Laminating Laminated
20 repetitions
E
NFC+Temp // SpO2
SpO2 layers
Jeong, Lu*, et al., Adv. Mater. Tech. 1900117 (2019).
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