Pathogen Safety/Security Assistance Pathogen Safety/Security - - PowerPoint PPT Presentation

Pathogen Safety/Security Assistance Pathogen Safety/Security Assistance Efforts of the United States Efforts of the United States

United States United States BWC Experts Meeting BWC Experts Meeting Geneva, August 2008 Geneva, August 2008

Long Long-

• term Commitment

term Commitment

• The United States has been providing

The United States has been providing assistance with pathogen safety and assistance with pathogen safety and security for nearly two decades. security for nearly two decades.

• Historic approach has been agency

Historic approach has been agency-

• driven

driven with general coordination of programs. with general coordination of programs.

• Congress and the Administration support

Congress and the Administration support these critical efforts with ongoing, these critical efforts with ongoing, significant, funding and policy emphasis. significant, funding and policy emphasis.

Agencies Actively Involved in Agencies Actively Involved in Assistance Efforts Assistance Efforts

• Department of State

Department of State

• Department of Energy

Department of Energy

• Department of Health and Human

Department of Health and Human Services Services

• Department of Agriculture

Department of Agriculture

• Department of Defense

Department of Defense

Presidential/Congressional Support Presidential/Congressional Support

• “

“ National Strategy to Combat WMD National Strategy to Combat WMD” ” (2002) Presidential Directive (2002) Presidential Directive

• “

“ Biodefense Biodefense for the 21 for the 21 st

st Century

Century” ” (2004) (2004)

• Nunn

Nunn-

• Lugar Cooperative Threat Reduction

Lugar Cooperative Threat Reduction (CTR) Initiated (1991) (CTR) Initiated (1991)

• Funding of 1+ billion dollars appropriated

Funding of 1+ billion dollars appropriated in biological arena in biological arena

Goals of Bio Threat Reduction Goals of Bio Threat Reduction

• Enhance safety, security, and

Enhance safety, security, and containment of dangerous biological containment of dangerous biological agents in bioscience facilities. agents in bioscience facilities.

• Strengthen capacities to detect and

Strengthen capacities to detect and control dangerous pathogens. control dangerous pathogens.

• Improve understanding and

Improve understanding and mitigation of biological threats. mitigation of biological threats.

Pathogen Safety/Security Pathogen Safety/Security Activities Activities

• Laboratory training

Laboratory training – – facility/ codes facility/ codes

• Cooperative biological research

Cooperative biological research

• Guideline development

Guideline development – –WHO, OECD WHO, OECD

• Drafting of legal measures

Drafting of legal measures

• Potential early warning of

Potential early warning of bioterror bioterror attacks and potential pandemics attacks and potential pandemics

State State Bio Bio-

• Engagement Program (BEP)

Engagement Program (BEP)

• Mission:

Mission: To engage scientists worldwide to prevent terrorist acquisitio To engage scientists worldwide to prevent terrorist acquisition n

• f dangerous biological materials, technology and expertise by:
• f dangerous biological materials, technology and expertise by:
• Promoting lab

Promoting lab biosafety biosafety and and biosecurity biosecurity; ;

• Safe, secure and sustainable lab capacity building to detect and

Safe, secure and sustainable lab capacity building to detect and respond to respond to disease outbreaks; disease outbreaks;

• Fostering transparent research and development; and

Fostering transparent research and development; and

• Promoting international collaborations and standardization.

Promoting international collaborations and standardization.

• Resources:

Resources: $26 million in fiscal year 2008; $29 million in fiscal year $26 million in fiscal year 2008; $29 million in fiscal year 2009. 2009.

• Partnerships with U. S. agencies, universities, and internationa

Partnerships with U. S. agencies, universities, and international organizations l organizations across the globe. across the globe.

• National Strategy I m plem entation:

National Strategy I m plem entation: Works across health, science, and Works across health, science, and security sectors to advance the 4 pillars of security sectors to advance the 4 pillars of “ “ U. S.

• U. S. Biodefense

Biodefense Strategy Strategy” ” : :

• Threat Awareness

Threat Awareness

• Prevention and Protection

Prevention and Protection

• Surveillance and Detection

Surveillance and Detection

• Response and Recovery

Response and Recovery

Provides dual Provides dual-

• benefit assistance to reduce the threat of bioterrorism

benefit assistance to reduce the threat of bioterrorism w hile com bating infectious disease w orldw ide. w hile com bating infectious disease w orldw ide.

State State

Guidelines Development/Training Guidelines Development/Training

• WHO Laboratory

WHO Laboratory Biosecurity Biosecurity Guidance Guidance

• Biosecurity

Biosecurity chapter of the chapter of the Biosafety Biosafety for for Microbiological and Biomedical Laboratories Microbiological and Biomedical Laboratories (BMBL) (BMBL)

• OECD Best Practices

OECD Best Practices Biosecurity Biosecurity Guidelines Guidelines

• CEN Laboratory

CEN Laboratory Biosecurity Biosecurity Management Management Guidelines Guidelines

• Funded development of WHO guidelines and

Funded development of WHO guidelines and materials for materials for biosecurity biosecurity

• Funding delivery of

Funding delivery of biosafety biosafety and and biosecurity biosecurity training in a training in a “ “ Train the Trainers Train the Trainers” ” format through format through WHO regional offices WHO regional offices

Energy Energy

• Laboratory

Laboratory biosafety biosafety, , biosecurity biosecurity, and , and biocontainment biocontainment world world-

• wide

wide

• Infectious disease diagnostics and control

Infectious disease diagnostics and control

• Training and workshops

Training and workshops

• Policy, regulatory, and guidelines support

Policy, regulatory, and guidelines support

• Assessments and analysis

Assessments and analysis

Health and Human Services Health and Human Services

• Regional laboratory

Regional laboratory biosfety biosfety and and biosecurity biosecurity fora fora in Central America, Africa, in Central America, Africa, and Asia and Asia

• Multi

Multi-

• nation Asian

nation Asian Biosafety Biosafety and and Biosecurity Biosecurity Conference Conference

• Support for a WHO project on

Support for a WHO project on “ “ Life Life Sciences R&D and Global Health Security Sciences R&D and Global Health Security

• CDC/ HHS serves as a WHO Collaborating

CDC/ HHS serves as a WHO Collaborating Center for Applied Center for Applied Biosafety Biosafety and Training and Training

Agriculture Agriculture

• Travel support for global leaders in animal health,

Travel support for global leaders in animal health, biosafety and biosecurity to participate in biosafety and biosecurity to participate in international meeting international meeting – – scheduled for later in scheduled for later in 2008, Paris, France 2008, Paris, France

• Goal: Establish a mechanism for Ministries of Agriculture

Goal: Establish a mechanism for Ministries of Agriculture to obtain training and advice on working safely and to obtain training and advice on working safely and securely with highly contagious animal and securely with highly contagious animal and zoonotic zoonotic pathogens. pathogens.

• Joint development of a biological safety training

Joint development of a biological safety training program with CDC for use by all federal response program with CDC for use by all federal response and research laboratories and eventually by the and research laboratories and eventually by the public world public world-

• wide.

wide.

• Scientific collaboration through the DOS Bio

Scientific collaboration through the DOS Bio-

• Engagement Program (BEP)

Engagement Program (BEP)

Defense Defense

• DoD

DoD’ ’s s Biological Threat Reduction Program (BTRP), works with Biological Threat Reduction Program (BTRP), works with partner governments to: partner governments to:

• strengthen capacity to detect, diagnose, and report

strengthen capacity to detect, diagnose, and report bioterror bioterror attacks attacks and potential pandemics and potential pandemics

• consolidate and secure dangerous pathogen collections and resear

consolidate and secure dangerous pathogen collections and research ch in centralized, secure facilities in centralized, secure facilities

• improve

improve biosafety biosafety practices practices

• conduct research on characterizing and mapping endemic infectiou

conduct research on characterizing and mapping endemic infectious s diseases diseases

• BTRP

BTRP’ ’s s comprehensive approach includes provision of diagnostic comprehensive approach includes provision of diagnostic laboratory infrastructure, training, and information technology laboratory infrastructure, training, and information technology

• BTRP is engaged in Azerbaijan, Georgia, Kazakhstan, Russia,

BTRP is engaged in Azerbaijan, Georgia, Kazakhstan, Russia, Ukraine, and Uzbekistan; expanding to Armenia (2008) Ukraine, and Uzbekistan; expanding to Armenia (2008)

• BTRP plans to add new partners this year

BTRP plans to add new partners this year

• Funding to date: $576 million

Funding to date: $576 million