London HIV Data Refresher data to end 2018 Meaghan Kall Principal - - PowerPoint PPT Presentation

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London HIV Data Refresher data to end 2018 Meaghan Kall Principal - - PowerPoint PPT Presentation

02/10/2019 London HIV Data Refresher data to end 2018 Meaghan Kall Principal Scientist Outline Epidemiological overview of London 2018 data highlighting gaps and disparities in: New HIV Diagnoses Late diagnosis


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London HIV Data Refresher data to end 2018

Meaghan Kall

Principal Scientist

02/10/2019

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Outline…

Epidemiological overview of London 2018 data – highlighting gaps and disparities in:

  • New HIV Diagnoses
  • Late diagnosis
  • Preventable deaths
  • Linkage to care and starting treatment
  • Adherence
  • Stigma
  • Living well

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New HIV Diagnoses

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HIV diagnoses among gay and bisexual men by region of residence: 2009 - 2018

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200 400 600 800 1,000 1,200 1,400 1,600 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

London Midlands and East of England North of England South of England Wales Northern Ireland Scotland

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HIV diagnoses among gay and bisexual men by demographic group: London, 2009 - 2018

HIV in the United Kingdom: 2019 Slide Set (version 1.0, published 3 September 2019)

400 800 1,200 White Black Asian Other/Mixed 200 400 600 800 1,000 15-24 25-34 35-49 50-64 ≥65

a) Age group, London b) Ethnicity, London c) Region of birth, London

100 200 300 400 500 600

UK Europe Asia Pacific North America Latin America Africa

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HIV diagnoses among people with heterosexual risk by region of residence: United Kingdom, 2009 - 2018

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200 400 600 800 1,000 1,200 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 London Midlands and East of England North of England South of England Wales Northern Ireland Scotland

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HIV diagnoses among people infected heterosexually: London, 2009 - 2018

a) Age group, London b) Ethnicity, London c) Region of birth, London

50 100 150 200 250 300 350

UK Europe Eastern Africa Western Africa Asia Latin America Other

100 200 300 400 500 600 700 800

White Black African Black Caribbean Black Other Asian Other/Mix

100 200 300 400 500 600 15-24 25-34 35-49 50-64 65+

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Late HIV Diagnoses

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Late HIV Diagnosis

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London England

HIV01: Late HIV diagnosis (CD4<350)

37% 44%

HIV01a: Very late HIV diagnosis (CD4<200)

21% 24% Late HIV diagnoses by exposure category and ethnicity, London 2015-2017

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New HIV diagnoses per 100,000 population by LA: 2017 Percentage diagnosed late (CD4<350) by LA of residence: 2015-2017

  • Late diagnosis

highest in outer London

  • New diagnosis

highest in central London

  • Higher Deprivation

(IMD)

  • No clear link to

Deprivation (IMD)

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Preventable Deaths

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AIDS at diagnosis and Deaths: London 2009 - 2018

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50 100 150 200 250 300 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 AIDS at HIV diagnoses Deaths

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Cause of deaths in Londoners with HIV: 2017 (n=179)

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17% (30/179) directly HIV- related and potentially preventable:

AIDS-defining illness (n=30), Diagnosed late (n=7), Patient not on ART because not adherent, lost to follow-up or chose not to be (n=8)

23% (42) not directly HIV- related but potentially preventable:

Lifestyle risk factors like smoking (n=8) and substance misuse (n=17), Suicide (n=8), Missed earlier HCV diagnosis and treatment (n=4), Vaccine-preventable infection – including HPV, influenza and measles (n=6)

Croxford et al. London HIV Death Audit poster FTC Conference 2019.

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Prevalence of co-morbidities among people who died by gender: London, 2017

Median age at death: 52 years [IQR: 44-64] Median time since diagnosis: 13 years

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Linkage to HIV care and treatment start

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16 National and Subnational 90-90-90 Calculations: UK Cities

Continuum of HIV care: London, 2018

People living with HIV 38,691 4.4/1,000 People diagnosed 36,690 95% On ART 35,925 98% Virally suppressed 34,847 97%

100% 95% 93% 90% People living with HIV People diagnosed with HIV On treatment Virally suppressed

London - All 98% 90% 81% 73% 95% 97% UNAIDS 90:90:90 target Estimated number of persons with viral load above 200 copies/L = 3,869 (0.44/1,000 residents) Number of new diagnosis in 2018 = 1504 Transmission ratio = 0.39

Population Estimates 2017 All ages 8,825,001 Aged 15-59 5,698,690

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Proportion of people1 on antiretroviral therapy with a viral load <200 copies/mL by age-group: England, 2018

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1 Includes people aged 15 and older

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Description London England HIV02b: Newly diagnosed adults seen for care within 1 month 82% 81% HIV03a: Virological success in people established on ART 96% 96% HIV03b: Virological success in people newly starting ART 97% 97% HIV04a: ART coverage (all adults) 99% 98% HIV04b: ART coverage (adults with the last CD4 count <350) 98% 97% HIV09aii: Retention in care (newly diagnosed) 87% 89% HIV09bii: Retention in care (all adults) 93% 94% HIV10: Time to treatment (initiating treatment within 91 days) 79% 83%

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HIV Dashboard Results 2018*

* Data will be updated with information from follow-up exercise

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Number of people seen for HIV care by age-group: London, 2009 - 2018

19 4,497 5,288 6,138 7,002 7,987 9,241 10,370 11,344 12,432 13,022 612 738 843 991 1,135 1,306 1,446 1,608 1,823 1,994

5000 10000 15000 20000 25000 30000 35000 40000 <15 15-24 25-34 35-49 50-64 ≥65

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Diagnosed HIV prevalence by residence

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  • Wide geographic variation (areas of >1% prevalence in 5 LAs)
  • Highest HIV rates in inner London

Diagnosed HIV prevalence by residence

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Diagnosed HIV prevalence (per 1,000 population women aged 15-59 years): England, 2017

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Local Authority Diagnosed HIV prevalence per 1,000 (aged 15-59) Barking and Dagenham 6.57 Lewisham 6.15 Southwark 6.11 Newham 5.51 Greenwich 5.26 Lambeth 5.24 Croydon 5.20

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Population prevalence by risk group

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  • Diagnosed prevalence: 134 (113-156) per 1,000 MSM in London
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Living Well Stigma & Discrimnation

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Methods

February – September 2017 Nationally representative

Random sample from HARS ~20% patients/clinic

Clinic-based recruitment

Face to face, post or email

Self-completion

Paper (87%) or online (13%)

Incentive

£5 high street voucher

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73 clinics

4,424 responses 51% response rate 2,146 Londoners

1 in 17 PLHIV in London

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Recruitment and participating clinics – London

56 Dean Street 250 Lewisham 109 Mortimer Market 248 Newham 99 Kobler, C&W 231 Woolwich 97 Royal Free 230 Homerton 84 St Marys 172 Barking 75 Barts & London 164 10HB, C&W 67 Kings 130 West Mid, C&W 45 St Georges 122 Whipps Cross 23

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HIV Clinic Satisfaction - London

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Over the past 2 years, HIV clinic satisfaction has...

62% stayed the same 32% increased 6% decreased

Average Clinic Rating

9.2

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HIV Treatment and Adherence London

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Smoking alcohol and drug use London region

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Drug use*

33% of London patients 25% in PLHIV nationally

*in past 3 months

Current smokers

20% London patients 21% in PLHIV nationally

Binge drinking*

39% of London patients 29% in PLHIV nationally

*≥8 units for men or ≥6 for women on one occasion in past 3 months

15% 10% 8% 9% 7% 6% 11% 3%

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Diagnosed Mental Health Conditions: London

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Depression

33% of PLHIV nationally 19% in the general population

Anxiety

25% of PLHIV nationally 15% in the general population

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Disclosure and Discrimination London

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Disclosure outside healthcare

In the past year, because

  • f your HIV have you...

14% worried about being discriminated

against in a healthcare setting

8% avoided seeking healthcare when

they needed it

4% actually been refused or delayed a

treatment or medical procedure

Discrimination in healthcare 13% 60% 52% 63% 20%

Nobody Friends Family Sexual Partners Other people

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% NEED % UNMET NEED

Met & Unmet Needs London

HIV RELATED SERVICES Information – living with HIV HIV treatment advice Adherence support Peer support Disclosure support Support managing LTC AVERAGE HEALTH SERVICES Psychologist or counsellor Stress management Weight management Advice regarding sex life Smoking cessation Alcohol counselling/treatment Drug counselling Chemsex support Drug detox Family planning Home health services AVERAGE SOCIAL & WELFARE SERVICES Housing support Meal or food services Childcare services Relationship advice Loneliness or isolation Employment advice Career skills and training Benefit claim support Financial advice Legal advice Immigration support Domestic violence services AVERAGE

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Case Study: Met & Unmet Needs

56 Dean Street + Kings College Hospital

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Service Needs: 56 Dean Street (n=250)

0% 10% 20% 30% 40% 50% 60% 70% 80%

Information - living with HIV HIV treatment advice Adherence support Peer support Disclosure support Support managing LTC Health services Psychologist or counsellor Stress management Weight management Advice regarding sex life Smoking cessation Alcohol counselling/treatment Drug counselling Chemsex support Drug detox Family planning Home health services Social and welfare services Housing support Meal or food services Childcare services Relationship advice Loneliness or isolation Employment advice Career skills and training Benefit claim support Financial advice Legal advice Immigration support Domestic violence services

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Service Needs: 56 DS(n=250) + Kings(n=130)

0% 10% 20% 30% 40% 50% 60% 70% 80%

Information - living with HIV HIV treatment advice Adherence support Peer support Disclosure support Support managing LTC Health services Psychologist or counsellor Stress management Weight management Advice regarding sex life Smoking cessation Alcohol counselling/treatment Drug counselling Chemsex support Drug detox Family planning Home health services Social and welfare services Housing support Meal or food services Childcare services Relationship advice Loneliness or isolation Employment advice Career skills and training Benefit claim support Financial advice Legal advice Immigration support Domestic violence services

56 Dean Street (n=250) King’s College Hospital (n=130)

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Unmet Needs: 56 DS(n=250) + Kings(n=130)

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Information - living with HIV HIV treatment advice Adherence support Peer support Disclosure support Support managing LTC Health services Psychologist or counsellor Stress management Weight management Advice regarding sex life Smoking cessation Alcohol counselling/treatment Drug counselling Chemsex support Drug detox Family planning Home health services Social and welfare services Housing support Meal or food services Childcare services Relationship advice Loneliness or isolation Employment advice Career skills and training Benefit claim support Financial advice Legal advice Immigration support Domestic violence services 56 Dean Street (n=250) King’s College Hospital (n=130)

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Key dates

4th September

  • HIV official statistics data release
  • 6 new profiles

24th October

  • 1. Spotlight report: HIV and Women
  • 2. Positive Voices report

14th November

  • HIV in the UK annual report

December

  • London HIV Spotlight report

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Acknowledgements

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We gratefully acknowledge the continuing collaboration of people living with HIV, as well as clinicians, microbiologists, immunologists, public health practitioners, occupational health doctors, nurses and other colleagues who contribute to the surveillance of HIV and STIs in the UK.