Do we need Proton Therapy? GEOFFREY IBBOTT RADIOLOGICAL PHYSICS - - PowerPoint PPT Presentation

do we need proton therapy
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Do we need Proton Therapy? GEOFFREY IBBOTT RADIOLOGICAL PHYSICS - - PowerPoint PPT Presentation

Do we need Proton Therapy? GEOFFREY IBBOTT RADIOLOGICAL PHYSICS CENTER HOUSTON, TEXAS Target Margin Display Distal Target Margins Proxim al Dose Profile Showing Modulated Depth Dosimetry and Calibration Standards Disagreement on width


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SLIDE 1

GEOFFREY IBBOTT RADIOLOGICAL PHYSICS CENTER HOUSTON, TEXAS

Do we need Proton Therapy?

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SLIDE 2

Target Margin Display

Target Margins

Proxim al Distal

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SLIDE 3

Dose Profile Showing Modulated Depth

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SLIDE 4

Dosimetry and Calibration Standards

Disagreement on

width of SOBP

Disagreement on

procedure to convert CT# to stopping power

General, but not

universal, agreement to use TRS-398

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SLIDE 5

Promising research/ development areas

  • 1. Delivery systems with selectable energy, scanning
  • 2. Standards for measurement, prescription and

reporting of dose

  • 3. IMPT
  • 4. Adaptive treatment for moving targets
  • 5. Therapeutic effectiveness to be demonstrated
  • 6. Adopt high-LET radiation

Jakel et. al., (2008) The future of heavy ion radiotherapy. Med. Phys. 35, 5653

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SLIDE 6

Proton Pelvis Phantom

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SLIDE 7

Phantom Treatment

Treatment plan created

with a prescription of 6 Gy to the prostate

Plan delivered 3 times

with film and TLD inserted in phantom

Plan accounting for

difference in patient and material SP to be delivered in near future

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SLIDE 8

TLD results

PTV Right PTV Left Femur Right Femur Left Institution Predicted Dose (cGy)

600.2 600.2 247.3 243.8

TLD Measured Dose (cGy)

589.8 595.1 242.1 240.4

Measured / Predicted Dose

0.983 0.992 0.979 0.986

PTV within 1.7% of predicted value Femur within 2.1% of predicted value

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SLIDE 9

To borrow from Dr. Vikram…

Should we study proton therapy?

Yes!

Should we use proton therapy outside

prospective clinical trials?

No!

Do we need standardized protocols for dose

measurement and specification?

Yes!