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Medication use review (MUR) in community pharmacies in Romania Cristina Rais, Adriana-Elena T erel Carol Davila University of Medicine and Pharmacy, Bucharest, Faculty of Pharmacy, Dept. of Management, Marketing and Pharmaceutical Legislation


  1. Medication use review (MUR) in community pharmacies in Romania Cristina Rais, Adriana-Elena T ă erel Carol Davila University of Medicine and Pharmacy, Bucharest, Faculty of Pharmacy, Dept. of Management, Marketing and Pharmaceutical Legislation NCPC Conference, November 28-30th, 2019 Narva-Jõesuu, Estonia

  2. Background Identifying Promoting proper Compounding Preventing use of medicines, Dispensing and health Resolving education DRP 2

  3. Aims of MUR pilot project in Romania • improve patients’ knowledge about their medication • enhance pharmacists’ communication competencies, as part of the health care team 3

  4. Methodology - identified poly- pharmacotherapy problems, Pharmacists - proposed relevant collected the solutions, data and Patients filling - set up a visit to prescriptions - analysed it - evaluate the general health percentages and treatment progress, 3 community situation, self- Likert scales pharmacies, - pharmacists health 3 GPs, communicated assessment and their findings to knowledge on the 5 pharmacists GPs prescribed medication - pharmacists asked for GP’s opinion on MUR service 4

  5. Results • 70 questionnaires of which 56 were validated • causes for invalidity: 1) prescriptions with < 5 medicines, 2) doctor's specialization other than GP, 3) insufficient information 5

  6. Patient information (I) Gender distribution Females Males 34% 66% Frecquency of patients on dietary requirements 3% 18% No diet 2% Low fat Low calories 34% 66% Hypoglycemic 43% Salt restriction 6

  7. Patient information (II) Frequency of patients' allergies No Unspecified etiology Ambrosia Pollen Dust Salicylates 2% 2% 11% 80% 20% 2% 3% • 43 patients do physical activity by walking • more than 90% declared they are not smokers or alcohol users 7

  8. Patient self-evaluation about personal medication use and general perception related to medications (I) Patients strongly agree that the following My health situation is .... are very important for them: 1. My health depends on medicines 64% 2. I am often concerned about the use of drugs 3. I understand my illness 30% 4. My health is 5% 0% 0% 5. I do not understand how medicines improve my health statements Very poor Poor Normal Good Very good 8

  9. Patient self-evaluation about personal medication use and general perception related to medications (II) Rank Statements I I rarely have difficulties getting my medication out of jar/blister Taking tablets is easy I rarely have problems to find my medications II I rarely don’t have enough money to pay for my medications III I rarely have difficulties swallowing medications IV 2% 11% V I rarely mix up different medications Never 28% I rarely have experienced adverse effects VI Rarely 16% Sometimes VII Taking medications has sometimes caused other problems Often VIII I sometimes forget to take my medications Very often 43% I sometimes have difficulties remembering dosages of my IX medications I am often concerned about the consequences of long term use X of medications 9

  10. Documentation for MUR service (I) Frequency of diseases HBP 34% 5% Vertigo Optical disorders 3% 15% Neurological disorders Hypercholesterolaemia 33% 3% Diabetes Thyroid disorders 5% 2% Anemia 0% 10% 20% 30% 40% 10

  11. Documentation for MUR service (II) Insomnia Hyperexcitability Gastric reflux Cough Hypokalemia Hyperacidity Muscle pain Vertigo Confusion Nausea Decreased blood pressure Sedative effect Side effects 11

  12. Documentation for MUR service (III) 12

  13. Pharmacist self-evaluation after MUR service Interview and preparation took on average 20 to 30 minutes. Pharmacists didn’t have difficulties (no additional training required) explaining the services to patients – effect, dosing, adverse reactions and communicate the findings to the doctors. In 10% of the cases the patients didn’t want to know more about the medication. 13

  14. MUR service feedback In average there were prescribed 6-7 Rx + 2-3 OTC + 2-3 supplements. 15% of the patients were prescribed more than 8 Rx medicines. The pharmacist prepared notes for GP if he/she identified drug related problems and also informed the patients. The pharmacist proposed solutions to patients and helped them to organize their medication. 14

  15. Conclusions Patients declared they were satisfied with the MUR service considering that explanations were understandable and taking into account the pharmacists advice. Physicians are reticent, for the time being, but generally in agreement with applying of MUR service. MUR project is ongoing. 15

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