CEPir Cell Enrichment Process for Isolation of Rare Cells w - PowerPoint PPT Presentation

物 生 澳 拓 CEPir Cell Enrichment Process for Isolation of Rare Cells 拓澳生物：w w w . t o p b i o x . c o m 邮箱：s a l e s @ t o p b i o x . c o m

BioCEP’s Vision 物 Lead the next generation of cell isolation devices which enable novel therapeutics and diagnostics by offering an advanced rare cell isolation technology which can 生 be integrated with front and downstream technologies 澳 拓 拓澳生物：w w w . t o p b i o x . c o m 2 邮箱：s a l e s @ t o p b i o x . c o m

The CEPir – C ell E nrichment P rocess for I solation of R are Cells 物 The CEPir is designed to overcome: 生  Cells aggregates  Membranes abrasions 澳  Cell clusters  Harmful aridity and plunging 拓  Limited magnetic fields 拓澳生物：w w w . t o p b i o x . c o m CEPir is a research use only device and may not be used for 3 邮箱：s a l e s @ t o p b i o x . c o m commercial applications

The Cell Enrichment Process A Novel Design for Effective Isolation 物 BioCEP’s patent protects the unique design which creates a closed magnetic field in which target cells are held in stasis, while non-target cells flow out of the 生 system. 澳 拓 BioCEP’s CEPir 拓澳生物：w w w . t o p b i o x . c o m 4 邮箱：s a l e s @ t o p b i o x . c o m

Unique Design 物 • 4 Isolation Areas for rare cell isolation Closed Magnetic Field • High Recovery 生 • Positive Isolations and Depletion • High Purity 澳 Target Cells Held in Stasis • High Viability • No Cell Abrasion or Clusters 拓 • Short Separation Time Flow Through • Allows Separation in Dialysis Method • Gentle On the Cells • Scenario Creation Flexible Software • Controlled Field Intensities, Concentrations and Volumes 拓澳生物：w w w . t o p b i o x . c o m 5 邮箱：s a l e s @ t o p b i o x . c o m

CEPir Electromagnets 物 Isolated Cells Held in Stasis within Buffer Fluid 生 澳 拓  Specimen flows through 4 separation areas  Variety of reagents and beads  Cell held in stasis  Up to 10 9 tagged cells  Controlled fields intensities  Gradient 拓澳生物：w w w . t o p b i o x . c o m 6 邮箱：s a l e s @ t o p b i o x . c o m

CEPir Flow Through Technology 物 生  Gentle passage  Quick Isolations  High volumes 澳  Option to work in batches  Dialysis option 拓 3 peristaltic pumps control the flow 拓澳生物：w w w . t o p b i o x . c o m 7 邮箱：s a l e s @ t o p b i o x . c o m

Flexible Software 物 Touchscreen Editor  Parameter control 生  Simple customization 澳 of loaded scenarios 拓 PC Editor  Endless scenario creations  Off-screen editing ease 拓澳生物：w w w . t o p b i o x . c o m 8 邮箱：s a l e s @ t o p b i o x . c o m

Cell Friendly Environment 物 Gentle flow through 生 Buffer prevents aridity 澳 Contact free - cells held in stasis 拓 Gentle degaussing Plunge free cell capture 拓澳生物：w w w . t o p b i o x . c o m 9 邮箱：s a l e s @ t o p b i o x . c o m

Viability ! Purity ! Recovery ! 物 生 Contam-ination Cell Viability (%) Purity (%) (%) vs. Competitor (%) CD 4 99.5 98.2 7.9 15 6 澳 CD 8 99 95.5 2.7 6 6 CD 19 98.9 86.5 1.1 33 18 拓 CD 15 99 91.2 3.9 10 19 CD 14 99.1 93.5 2.2 16 8 拓澳生物：w w w . t o p b i o x . c o m 10 邮箱：s a l e s @ t o p b i o x . c o m

The CEPir Advantage 物  High recovery, purity, viability  Rare cell isolation (1 in 10 9th cells) 生  No cell abrasions, aggregates  Flow through, short process 澳 拓  0.5-50 ml per batch up to 10 9th tagged cells  Software controlled  Fits under a hood for sterile isolations 拓澳生物：w w w . t o p b i o x . c o m 11 邮箱：s a l e s @ t o p b i o x . c o m

Technical Spec 物  Power: AC100v-240v 600w 22 in  Operating Temp: 5-40 ℃ 生  Operating Humidity: 0-85%  Environmental: RoHS Compliant 澳  Safety: EN60950-1/2006 21.7 in 55 cm  EMI: EN55022/2006 Class A  Interface: USB, TCP/IP, RS-232, WiFi 拓 56 cm Fits under a hood for sterile isolations 拓澳生物：w w w . t o p b i o x . c o m 12 邮箱：s a l e s @ t o p b i o x . c o m

Simple Kit Installation 物 生 澳 拓 拓澳生物：w w w . t o p b i o x . c o m 13 邮箱：s a l e s @ t o p b i o x . c o m

物 生 澳 拓 For More Information on the CEPir www.biocep.com 拓澳生物：w w w . t o p b i o x . c o m 邮箱：s a l e s @ t o p b i o x . c o m