an update from the Global Burden of Disease Study Catherine O. - - PowerPoint PPT Presentation

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an update from the Global Burden of Disease Study Catherine O. - - PowerPoint PPT Presentation

Mar 01, 2024 182 likes •427 views

Global trends in cardiovascular disease - an update from the Global Burden of Disease Study Catherine O. Johnson, PhD MPH Lead Research Scientist, IHME Cardiovascular Group Global Burden of Disease Captures all forms of health loss (death,

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Global trends in cardiovascular disease - an update from the Global Burden of Disease Study

Catherine O. Johnson, PhD MPH Lead Research Scientist, IHME Cardiovascular Group

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Global Burden of Disease

  • Captures all forms of health loss (death, sickness, injury)
  • Covers all potential diseases, injuries, and impairments
  • Generates comprehensive and comparable estimates
  • Facilitates comparisons between different types of health loss
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Over 20 years of innovation on GBD

1991: GBD

  • riginated

by the World Bank and WHO 1993: Prelim. results published in World Development Report 2007: IHME established to catalyze new era of GBD innovation 2015: WHO and IHME sign MOU; European BoD Network formed

1990 2000 Today 2010

1996-7: Final results published 2016: IHME begins annual updates to GBD as global public good

Publication of updated GBD results

2018: IHME and WHO sign new MOU to strengthen GBD efforts and uptake

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4

GBD is a global effort

3,641 collaborators 143 countries 2 territories

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Four “Building Blocks” of Estimation

All-cause Mortality

“How many people died?”

Causes of Death

“What do they die from?”

Risk Factors

“What’s causing this death and sickness?”

Non-Fatal Outcomes

“What makes people sick?”

YLLs, DALYs, YLDs, HALE

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Building Blocks: Cause of Death

All-cause Mortality Causes of Death

  • Estimation of specific causes of death by

age & sex.

  • Estimates then fit to all-cause mortality

estimates.

  • Cause list is mutually exclusive and collectively

exhaustive.

  • Important for informing health policy and

interventions.

Risk Factors Non-Fatal Outcomes

YLLs, DALYs, YLDs, HALE

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ICD: Cause Map

  • The cause list is mapped to ICD

codes

  • Each cause is mapped to one or

many ICD codes

  • Many iterations of ICD codes, such as

ICD-9, ICD-9 BTL, ICD-10

  • Causes mapped to each ICD iteration

to capture all possible codes in available data for each cause

7

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Redistribution of Garbage Codes

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Unspecified Stroke

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Heart Failure

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Cardiovascular Deaths

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Cardiovascular Deaths

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Cardiovascular Deaths – 50 to 69 years

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Cardiovascular Deaths – 70+ years

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Risk Factors

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Risk Factors – Systolic Blood Pressure

Exposure

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Risk Factors – LDL Cholesterol

Exposure

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Risk Factors - Smoking

Exposure

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Risk Factors – Fasting Plasma Glucose

Exposure

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Global Burden of Disease

  • Results visualization:
  • https://vizhub.healthdata.org/gbd-compare/
  • Results query tool:
  • http://ghdx.healthdata.org/gbd-results-tool
  • Input data sources:
  • http://ghdx.healthdata.org/gbd-2017/data-input-sources
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Global Burden of Disease

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Global Burden of Disease

  • Results visualization:
  • https://vizhub.healthdata.org/gbd-compare/
  • Results query tool:
  • http://ghdx.healthdata.org/gbd-results-tool
  • Input data sources:
  • http://ghdx.healthdata.org/gbd-2017/data-input-sources
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Thank you