Allergy and Hypersensitivity K. J. Goodrum 2005 1 Fig.12.6 Early - PowerPoint PPT Presentation

Allergy and Hypersensitivity K. J. Goodrum 2005 1

Fig.12.6 Early IL-4 response promotes Th2 development that drives B cell class switching to IgE Secreted IgE “sensitizes” mucosal and connective tissue mast cells. Secreted factors from activated mast cells Fig.12.7 Fig.12.10 2

Acute ,Late, and Chronic phase Type I Reactions. Secreted factors from activated eosinophils Fig. 12.12 Fig.12.16 Treatment of Type I Hypersensitivity Fig.12.18 3

Fig. 13.8 Type II Cytotoxic reaction SERUM SICKNESS (Type III ARTHUS REACTION (Type III hypersensitivity reaction) hypersensitivity reaction) 4

ALLERGIC CONTACT DERMATITIS (Type IV hypersensitivity reaction) Fig. 12.21 Delayed Type Hypersensitivity or DTH (Type IV hypersensitivity reaction) 5