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Zhao-Bang Zeng Develop computa?onal tools for the whole pipeline - PowerPoint PPT Presentation

GT4SP (Genomic Tools for Sweetpotato Improvement) https://sweetpotatogenomics.cals.ncsu.edu/ Zhao-Bang Zeng Develop computa?onal tools for the whole pipeline data analysis. Build rela?onship Genomics-informed Filter out between genome Ma?ng


  1. GT4SP (Genomic Tools for Sweetpotato Improvement) https://sweetpotatogenomics.cals.ncsu.edu/ Zhao-Bang Zeng • Develop computa?onal tools for the whole pipeline data analysis. Build rela?onship Genomics-informed Filter out between genome Ma?ng design or informa?on and phenotypes gene?c engineering MAPPoly Raw DNA Marker Linkage Breeding è QTL è è è è Selec?on Sequences Genotypes Map By Design SuperMASSA QTLPoly Build genome Use the inferred rela?onship rela?onship • Sweetpotato is one of the most complex gene?c systems for breeding due to (auto)hexaploid (6x). • If we can solve the whole analy?cal problems for this system, we can use it or adapt it for almost any system.

  2. Autohexaploid complexity 9/5/18 2

  3. Genotype calling SuperMASSA

  4. Sweetpotato map - 22,793 SNPs Tf and Tl (private) MAPPoly Tf_Tl (shared) Mb cM

  5. QTL mapping QTLPoly

  6. QTL Characterization: NOCR (ha) QTLPoly 9/5/18 6

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