Update on Diagnosis and Treatment of Melanoma February 4, 2017 - - PowerPoint PPT Presentation

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Nov 09, 2022 359 likes •436 views

35th Annual Leland R Cowan Cancer Symposium: Update on Diagnosis and Treatment of Melanoma February 4, 2017 AJCC 7th Edition Staging of Malignant Melanoma: TX: cant be assessed, eg curettage or regressed melanoma T0: No evidence of

SLIDE 1

35th Annual Leland R Cowan Cancer Symposium:

Update on Diagnosis and Treatment of Melanoma

February 4, 2017

SLIDE 2

AJCC 7th Edition Staging of Malignant Melanoma:

TX: can’t be assessed, eg curettage or regressed melanoma
T0: No evidence of primary tumor
Tis: melanoma in situ
T1: < 1mm thick
a=no ulceration, <1sq mm, b=with ulceration, >1sq mm
T2: 1.01-2mm thick
a = no ulceration, b = with ulceration
T3: 2.01-4mm thick
a = no ulceration, b = with ulceration
T4: > 4mm thick
a = no ulceration, b = with ulceration

SLIDE 3

AJCC 7th Edition Staging of Malignant Melanoma:

NX: Regional nodes can’t be assessed
N0: No regional metastases detected
N1: 1 node with metastatic disease
a=micrometastasis, b=macrometastasis
N2: 2-3 + nodes
a=micro, b=macro, c=in transit met, without

nodal metastases

N3: 4 or more metastatic nodes, or matted nodes
r in transit met with metastatic nodes

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AJCC 7th Edition Staging of Malignant Melanoma:

M0: No evidence of distant metastases
M1a: Metastases to skin, subcutaneous or

distant lymph nodes

M1b: Metastases to lung
M1c: Metastases to all other visceral sites or

elevated LDH

SLIDE 5

Stage Groupings, Clinical:

Stage 0: Tis N0 M0
IA: T1a N0 M0
IB: T1b, T2a, N0 M0
IIA: T2b, T3a, N0 M0
IIB: T3b, T4a, N0 M0
IIC: T4b N0 M0
III: Any T N>1 M0
IV: Any T Any N M1

SLIDE 6

Pathologic Stage Grouping:

0-IIC are exactly the same as clinical staging
IIIA: T1-4a N1a, 2a M0
IIIB: T1-4b N1a, N2a M0
T1-4a N1b, N2b, N2c M0
IIIC: T1-4b N1b, N2b, N2c M0
Any T N3 M0
IV: Any T Any N M1