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The burden of cancer in emerging economies: Productivity loss as an alternative perspective Alison Pearce, Paul Hanly, Linda Sharp, Isabelle Soerjomataram ISPOR 2015 Cancer in emerging economies Cancer deaths Cancer diagnoses Developed


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The burden of cancer in emerging economies: Productivity loss as an alternative perspective

Alison Pearce, Paul Hanly, Linda Sharp, Isabelle Soerjomataram

ISPOR 2015

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Cancer in emerging economies

Developing countries 54% Developed countries 46%

Cancer diagnoses

Developing countries 64% Developed countries 36%

Cancer deaths

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BRICS countries

World’s Population World’s Land area World’s GDP

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Burden of cancer

Everyone’s work contributes to the economy, and not working represents a loss of this contribution to society

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Aim

To estimate the value of lost productivity due to cancer-related premature mortality in Brazil, Russia, India, China and South Africa (BRICS) in 2012

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Methods & Data

  • Incidence-based, human capital approach
  • GLOBOCAN data
  • Cancer mortality rates
  • OECD & ILO data
  • Workforce participation & unemployment
  • Wages & future wage growth
  • Retirement ages
  • Local currency calculations converted to USD

using PPP and inflation to 2012

  • 3% discounting
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Demographic inputs

Population (millions) Cancer deaths Life expectancy Brazil 201 222,505 73.8 China 1,357 2,194,746 75.3 India 1,211 673,098 66.4 Russia 144 294,522 68.0 South Africa 52 46,953 57.0

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Wage inputs

Monthly wage (USD) Wage growth rate Brazil $1,069 2.0% China $172 3.7% India $415 4.2% Russia $7,100 2.4% South Africa $2,631 2.8%

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Workforce inputs

Gender Participation Unemployment Retire

(eg 40-45) (eg 40-45)

age Brazil Male 93.56 2.24 65 Female 71.44 4.83 60 China Male 96.50 1.87 60 Female 84.82 2.60 50 India Male 98.10 1.12 60 Female 37.10 1.35 58 Russia Male 94.23 4.07 58 Female 91.24 3.47 55 South Africa Male 85.45 15.96 60 Female 67.07 17.24 60

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Deaths & YPLL

100 200 300 400 500 600 Male Female Male Female Male Female Male Female Male Female Brazil China India Russia Sth Africa

Deaths & Years of Productive Life Lost

Deaths (1,000s) YPLL (10,000s)

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Total cost & cost per death

$0 $20,000 $40,000 $60,000 $80,000 $100,000 $0 $5 $10 $15 $20 $25 Male Female Male Female Male Female Male Female Male Female Brazil China India Russia Sth Africa Billions

Total cost and cost per death

Total Cost Cost per death

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Results by cancer

0% 20% 40% 60% 80% 100% Brazil China India Russia South Africa

Brain, nervous system Prostate Cervix uteri Breast Melanoma of skin Lung Liver Colorectum Stomach Oesophagus

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Sensitivity Analyses

  • Divide Chinese data by urban and rural
  • Increase workforce participation in India
  • Increase retirement ages in China & Russia
  • Changing growth rates & discounting

No major changes to the findings

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Limitations

  • Concerns about equity with the Human

Capital Approach

  • Lack of data
  • Assumptions around employment (informal

economies and household production)

  • But… valuing cancer related lost

productivity can provide policy makers with an additional perspective when identifying priorities for cancer prevention and control

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Implications

  • Prevention activities are important, and

need to extend beyond tobacco control

  • Earlier detection and improved treatment

availability to reduce mortality may be economically efficient

  • Potential increase in cancer burden

through ageing, urbanisation and westernisation

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Acknowledgements

  • International collaborators: Freddie Bray, Prakash Gupta,

You-Lin Qiao, Freddy Sitas, Anton Barchuk, Marianna de Camargo Cancela

  • COST Action IS1211 CANWON funded a Short Term

Scientific Mission for Alison Pearce, to IARC, to establish this project

  • Alison Pearce is funded by an HRB ICE Award
  • The NCRI is funded by the Department of Health
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Contacts

Alison Pearce ICE Post-doctoral Research Fellow National Cancer Registry Ireland a.pearce@ncri.ie @aliepea