Technique Of Carotid Technique Of Carotid Stenting Stenting - - PowerPoint PPT Presentation

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Technique Of Carotid Technique Of Carotid Stenting Stenting - - PowerPoint PPT Presentation

Technique Of Carotid Technique Of Carotid Stenting Stenting Decision Making Analysis To Overcome Decision Making Analysis To Overcome Challenges Challenges Subbarao Myla MD FACC Subbarao Myla MD FACC Hoag Memorial Hospital Presbyterian


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SLIDE 1

Technique Of Carotid Technique Of Carotid Stenting Stenting

Decision Making Analysis To Overcome Decision Making Analysis To Overcome Challenges Challenges

Subbarao Myla MD FACC Subbarao Myla MD FACC

Hoag Memorial Hospital Presbyterian Hoag Memorial Hospital Presbyterian Newport Beach, CA Newport Beach, CA USA USA

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SLIDE 2

Presenter Disclosure Information

Name: Subbarao Myla, MD

Within the past 12 months, the presenter or their spouse/partner have had the financial interest/arrangement or affiliation with the organization listed below.

Company Name: Relationship:

  • Johnson & Johnson

Research Grant/Speaker

  • Guidant

Research Grant/Speaker

  • Boston Scientific

Research Grant/Speaker

  • Abbott

Research Grant/Speaker

  • Enotex

Research Grant/Speaker

  • EV3

Research Grant/Speaker

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SLIDE 3

Critical Decision Making Critical Decision Making

 Carotid Access Issues

Carotid Access Issues

 Carotid Filter Issues

Carotid Filter Issues

 Carotid Stent Issues

Carotid Stent Issues

 Neuro Rescue

Neuro Rescue

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SLIDE 4

Carotid Access Carotid Access

 Can I Safely Get There?

Can I Safely Get There?

– CCA Access CCA Access

 Can I Safely Get There?

Can I Safely Get There?

– Distal Protection Device into ICA Distal Protection Device into ICA

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SLIDE 5

Critical Issues Critical Issues

 Which Carotid Access Technique?

Which Carotid Access Technique?

– Front Loading Telescopic Technique Front Loading Telescopic Technique – Back Loading Serial Stiffening Technique Back Loading Serial Stiffening Technique – TAD Wire Method TAD Wire Method – Remote Carotid Access Remote Carotid Access

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SLIDE 6

Carotid Access Determinants Carotid Access Determinants

 Aortic Arch Type

Aortic Arch Type

 CCA/ECA Disease

CCA/ECA Disease

 Carotid Tortuosity

Carotid Tortuosity

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SLIDE 7

Arch Types (Myla 1996) Arch Types (Myla 1996)

Type I Arch Type II Arch Type III Arch

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SLIDE 8

Aortic Arch Aortic Arch

 Need to visualize the arch

Need to visualize the arch

– Assess the Arch Type Assess the Arch Type

  • Type I

Type I

  • Type II

Type II

  • Type III

Type III

– Arch Disease Arch Disease

  • Ulceration

Ulceration

  • Atheroma

Atheroma

– Arch Anomalies Arch Anomalies – Ostial Stenosis Ostial Stenosis

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SLIDE 9

Aortic Arch Aortic Arch

 Need to visualize the arch

Need to visualize the arch

– Assess the Arch Type Assess the Arch Type

  • Type I

Type I

  • Type II

Type II

  • Type III

Type III

– Arch Disease Arch Disease

  • Ulceration

Ulceration

  • Atheroma

Atheroma

– Arch Anomalies Arch Anomalies – Ostial Stenosis Ostial Stenosis

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SLIDE 10

Aortic Arch Aortic Arch

 Need to visualize the arch

Need to visualize the arch

– Assess the Arch Type Assess the Arch Type

  • Type I

Type I

  • Type II

Type II

  • Type III

Type III

– Arch Disease Arch Disease

  • Ulceration

Ulceration

  • Atheroma

Atheroma

– Arch Anomalies Arch Anomalies – Ostial Stenosis Ostial Stenosis

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SLIDE 11

Aortic Arch Aortic Arch

 Need to visualize the arch

Need to visualize the arch

– Assess the Arch Type Assess the Arch Type

  • Type I

Type I

  • Type II

Type II

  • Type III

Type III

– Arch Disease Arch Disease

  • Ulceration

Ulceration

  • Atheroma

Atheroma

– Arch Anomalies Arch Anomalies – Ostial Stenosis Ostial Stenosis

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SLIDE 12

Carotid Access Determinants Carotid Access Determinants

 Aortic Arch Type

Aortic Arch Type

– Type I Arch Type I Arch

  • Telescopic Method

Telescopic Method_Cook Shuttle Select _Cook Shuttle Select

– Type II Arch Type II Arch

  • Serial Stiffening Method_SM2 Supracore_Shuttle

Serial Stiffening Method_SM2 Supracore_Shuttle

– Type III Arch Type III Arch

  • Remote Access_Vitek_8F JCL 3.5

Remote Access_Vitek_8F JCL 3.5

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SLIDE 13

Carotid Access Determinants Carotid Access Determinants

 CCA/ECA Disease

CCA/ECA Disease

– Type I Arch Type I Arch

  • Simple Lesion

Simple Lesion

– TAD Wire method TAD Wire method

  • Complex Lesion

Complex Lesion

– 0.038 Stiff Angled Glide 0.038 Stiff Angled Glide in CCA method in CCA method

– Type II Arch Type II Arch

  • 0.038 Stiff Angled

0.038 Stiff Angled Glide/Nitrex Wire Glide/Nitrex Wire method method

– Type III Arch Type III Arch

  • Remote Access with Guide

Remote Access with Guide catheter catheter

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SLIDE 14

Carotid Access Determinants Carotid Access Determinants

 Carotid Tortuosity

Carotid Tortuosity

– Type I Arch Type I Arch

  • Telescopic access

Telescopic access

  • Serial Stiffening Method

Serial Stiffening Method

– Type II Arch Type II Arch

  • Serial Stiffening Method

Serial Stiffening Method

  • Remote Access

Remote Access

– Type III Arch Type III Arch

  • Avoid Them

Avoid Them

  • Direct Carotid Stick

Direct Carotid Stick

  • Remote Carotid Access

Remote Carotid Access

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SLIDE 15

Critical Issues Critical Issues

 Should I Choose Guide Catheter or

Should I Choose Guide Catheter or Guide Sheath? Guide Sheath?

 Should I Keep Guide C/S In distal CCA

Should I Keep Guide C/S In distal CCA

  • r proximal CCA?
  • r proximal CCA?

 When do I choose large size Guide

When do I choose large size Guide C/S? C/S?

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SLIDE 16

Critical Issues Critical Issues

 Should I Choose Guide Catheter or

Should I Choose Guide Catheter or Guide Sheath? Guide Sheath?

– Individual Preference Individual Preference

  • GC more stable allows torque

GC more stable allows torque

  • GS smaller size smoother transition (No ledge

GS smaller size smoother transition (No ledge effect) effect)

– Carotid Tortuosity Carotid Tortuosity

  • GC allows torque

GC allows torque

– Remote carotid access Remote carotid access

  • GC More stable

GC More stable

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SLIDE 17

Critical Issues Critical Issues

 When do I choose large size Guide C/S?

When do I choose large size Guide C/S? – Usual Sizes Usual Sizes

  • Guide Sheath

Guide Sheath 6F 6F Larger Size Larger Size 7F 7F

  • Guide Catheter

Guide Catheter 8F 8F Larger Size Larger Size 9F 9F – Large Sizes Large Sizes

  • Anticipate Buddy wires

Anticipate Buddy wires – Carotid Tortuosity Carotid Tortuosity

  • Beginner

Beginner – Avoid air embolism Avoid air embolism – Allow contrast injection for precise device Allow contrast injection for precise device placement placement

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SLIDE 18

Carotid Filter Issues Carotid Filter Issues

 Should I Pre-dilate Before Filter

Should I Pre-dilate Before Filter Placement? Placement?

 What to do with slow

What to do with slow Flow/occlusion in a filter? Flow/occlusion in a filter?

– Is this Filled Filter? Is this Filled Filter? – Is this carotid Spasm? Is this carotid Spasm?

 What is happening at the filter site?

What is happening at the filter site?

– Is this Spasm, Kink or dissection? Is this Spasm, Kink or dissection?

 What do to when the retrieval

What do to when the retrieval sheath fails to advance? sheath fails to advance?

 How to Handle a detached filter?

How to Handle a detached filter?

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SLIDE 19

Carotid Filter Issues Carotid Filter Issues

 What to do when filter doesn’t

What to do when filter doesn’t Advance? Advance?

– Poor guide support Poor guide support – Carotid tortuosity Carotid tortuosity – Severe stenosis Severe stenosis – Large filter Large filter – Sharp entry angle Sharp entry angle – Sharp exit angle Sharp exit angle

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SLIDE 20

Internal Internal Carotid Artery Carotid Artery

 Sharp Entry angle

Sharp Entry angle

 Sharp Exit angle

Sharp Exit angle

 Distal ICA bends

Distal ICA bends

 Distal ICA kinks

Distal ICA kinks

 Distal ICA loops

Distal ICA loops

 FMD

FMD

 Arteriosclerosis

Arteriosclerosis

 Aneurysm

Aneurysm

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SLIDE 21

Internal Internal Carotid Artery Carotid Artery

 Sharp Entry angle

Sharp Entry angle

 Sharp Exit angle

Sharp Exit angle

 Distal ICA bends

Distal ICA bends

 Distal ICA kinks

Distal ICA kinks

 Distal ICA loops

Distal ICA loops

 FMD

FMD

 Arteriosclerosis

Arteriosclerosis

 Aneurysm

Aneurysm

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SLIDE 22

Carotid Filter Issues Carotid Filter Issues

 What to do when

What to do when filter doesn’t filter doesn’t Advance? Advance?

– Solutions Solutions

  • Power Guide support

Power Guide support

  • Pre-dilatation

Pre-dilatation

  • Buddy Wire

Buddy Wire

  • Buddy Catheter

Buddy Catheter

  • Bare wire/Spyder

Bare wire/Spyder

  • Percusurge

Percusurge

  • Proximal Protection

Proximal Protection

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SLIDE 23

Carotid Filter Issues Carotid Filter Issues

 Should I Pre-dilate Before

Should I Pre-dilate Before Filter placement? Filter placement?

– Carotid Tortuosity Carotid Tortuosity

  • Fixed Wire Filters

Fixed Wire Filters

– Pre-dilate severe stenosis Pre-dilate severe stenosis – Reduces friction during filter Reduces friction during filter travel travel

  • Bare Wire Filters

Bare Wire Filters

– No need to pre-dilate No need to pre-dilate

  • In situ Wire Filters (Spyder)

In situ Wire Filters (Spyder)

– No need to pre-dilate No need to pre-dilate

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SLIDE 24

Carotid Filter Issues Carotid Filter Issues

 Should I Pre-dilate

Should I Pre-dilate Before Filter Before Filter placement? placement?

– Carotid Lesion Severity Carotid Lesion Severity

  • Pre-dilate for

Pre-dilate for subtotal occlusions subtotal occlusions

– Segmental Segmental – Long lesions Long lesions – String signs String signs

  • No need to pre-dilate

No need to pre-dilate

– Short Short – Focal subtotal Focal subtotal

  • cclusions
  • cclusions
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SLIDE 25

Carotid Filter Issues Carotid Filter Issues

 Should I Pre-dilate

Should I Pre-dilate Before Filter Before Filter placement? placement?

– Carotid Complex Carotid Complex Lesion Morphology Lesion Morphology

  • Sharp Entry Angle

Sharp Entry Angle

  • Sharp Exit Angle

Sharp Exit Angle

  • Absent clear path

Absent clear path through Lesion through Lesion

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SLIDE 26

Carotid Filter Issues Carotid Filter Issues

 Should I Pre-dilate Before

Should I Pre-dilate Before Filter placement? Filter placement?

– Carotid Filter Profile Carotid Filter Profile

  • Large Bulky Filters

Large Bulky Filters

– Pre-dilate Pre-dilate

  • Small Filters

Small Filters

– No need to pre-dilate No need to pre-dilate

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SLIDE 27

Carotid Stent Issues Carotid Stent Issues

 Should I Pre-dilate Before

Should I Pre-dilate Before Stent placement? Stent placement?

 What Stent Dimensions Should

What Stent Dimensions Should I Choose? I Choose?

 Should I Post Dilate After

Should I Post Dilate After Stent Placement? Stent Placement?

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SLIDE 28

Carotid Stent Issues Carotid Stent Issues

 Should I Pre-dilate Before

Should I Pre-dilate Before Stent placement? Stent placement?

– Carotid Stent Profile Carotid Stent Profile – Carotid Lesion Severity Carotid Lesion Severity – Carotid Tortuosity Carotid Tortuosity – Operator Experience Operator Experience – Carotid Lesion Complex Carotid Lesion Complex Morphology Morphology

  • Sharp Entry Angle

Sharp Entry Angle

  • Sharp Exit Angle

Sharp Exit Angle

  • Heavy Calcification

Heavy Calcification

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SLIDE 29

Carotid Stent Issues Carotid Stent Issues

 Should I Post Dilate

Should I Post Dilate After Stent Placement? After Stent Placement?

– Objectives Objectives

  • Minimal Final lumen

Minimal Final lumen diameter diameter

  • Safe retrieval of DPD

Safe retrieval of DPD

  • Avoid Stent migration

Avoid Stent migration

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SLIDE 30

Carotid Stent Issues Carotid Stent Issues

 Should I Post Dilate After

Should I Post Dilate After Stent Placement? Stent Placement?

– Carotid Stent Type Carotid Stent Type

  • Closed Cell Design

Closed Cell Design

  • Open Cell Design

Open Cell Design

– Carotid Lesion Type Carotid Lesion Type

  • Heavily Calcified

Heavily Calcified

– Residual Lesion severity Residual Lesion severity

  • Large residual

Large residual

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SLIDE 31

Carotid Landing Zone Issues Carotid Landing Zone Issues

 What to do with Inadequate

What to do with Inadequate Landing Zone? Landing Zone?

– Can this be modified? Can this be modified?

  • Buddy wire

Buddy wire

  • BareWire

BareWire

  • More proximal placement of Guide

More proximal placement of Guide sheath in CCA to relax the vessel sheath in CCA to relax the vessel

  • PTA/stenting of stenosis

PTA/stenting of stenosis

– No No

  • CEA

CEA

  • Proximal Protection

Proximal Protection

  • Unprotected stenting

Unprotected stenting

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SLIDE 32

Carotid Filter Issues Carotid Filter Issues

 What to do with slow

What to do with slow flow/occluded Filter? flow/occluded Filter?

– Are Filter Dots Closed? Are Filter Dots Closed?

  • Yes

Yes

– Carotid Spasm Carotid Spasm – Give Nitro Give Nitro

  • No

No

– Filter slow flow due to emboli Filter slow flow due to emboli – Retrieve Filter Retrieve Filter

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SLIDE 33

Carotid Filter Issues Carotid Filter Issues

 What to do with slow

What to do with slow flow/occluded Filter? flow/occluded Filter?

– Angioguard/Rubicon/Filterwire/Accu Angioguard/Rubicon/Filterwire/Accu net net

  • Filling defect below filter dots

Filling defect below filter dots

– Aspirate with Percusurge Export Aspirate with Percusurge Export – Close Filter Close Filter

  • Filling defect above filter dots

Filling defect above filter dots

– Close filter and remove Close filter and remove

  • Incidence

Incidence

– Slow flow Slow flow 10- 20% 10- 20% – Aspiration 2-5% Aspiration 2-5%

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SLIDE 34

Carotid Filter Issues Carotid Filter Issues

 What to do when Retrieval

What to do when Retrieval sheath doesn’t advance? sheath doesn’t advance?

– Anatomical Adversity Issues Anatomical Adversity Issues

  • Carotid Tortuosity

Carotid Tortuosity

  • Sharp Lesion Angles

Sharp Lesion Angles

  • Guide wire bias

Guide wire bias

  • Inadequate post dilatation

Inadequate post dilatation

  • Open cell stent design with

Open cell stent design with “gater backing” “gater backing”

  • Calcified lesion

Calcified lesion

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SLIDE 35

DPD Retrieval Catheter Issues DPD Retrieval Catheter Issues

 Retrieval Catheter (RC)

Retrieval Catheter (RC)

– Close Cell vs. Open Cell Design Close Cell vs. Open Cell Design – Carotid Adverse Anatomy Carotid Adverse Anatomy

  • Tortuosity

Tortuosity

  • Sharp Lesion Angle

Sharp Lesion Angle

  • Heavily Calcified Lesion

Heavily Calcified Lesion

  • Significant Residual Lesion

Significant Residual Lesion

– RC Design RC Design

  • Coaxial System

Coaxial System

  • Single Stiff catheter

Single Stiff catheter

  • Single Soft Catheter

Single Soft Catheter

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SLIDE 36

DPD Retrieval Catheter Issues DPD Retrieval Catheter Issues

 Retrieval Catheter (RC)

Retrieval Catheter (RC)

– Closed Cell stent Closed Cell stent

  • Least Problems

Least Problems

  • Neutralizes anatomical adversity

Neutralizes anatomical adversity

– Open cell stent Open cell stent

  • Worst Problems

Worst Problems

  • Single Stiff Recovery Catheter

Single Stiff Recovery Catheter

  • Anatomical Adversity

Anatomical Adversity

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SLIDE 37

Carotid Filter Issues Carotid Filter Issues

 What to do when retrieval sheath doesn’t

What to do when retrieval sheath doesn’t advance? advance?

– Don’t panic and pull on filter! Don’t panic and pull on filter! – Neck rotation Neck rotation – Advance sheath distally Advance sheath distally – Neck compression Neck compression – Bent tip retrieval sheath Bent tip retrieval sheath – Buddy-wire Buddy-wire – Additional balloon dilatations Additional balloon dilatations

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SLIDE 38

Filter Detachment Filter Detachment

 RC Catheter advancement

RC Catheter advancement problem problem

 Filter slides down and

Filter slides down and impinges on stent impinges on stent

 Guide catheter prolapse

Guide catheter prolapse into Aorta pulls Filter down into Aorta pulls Filter down

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SLIDE 39

Filter Detachment Filter Detachment

 Preventive Strategies

Preventive Strategies

– Avoid cases with poor landing Avoid cases with poor landing zone zone – Always Keep guide tip in view Always Keep guide tip in view – Never force pull Filter into RC Never force pull Filter into RC – Use salvage Measures for RC Use salvage Measures for RC problems problems – Change RC type Change RC type

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SLIDE 40
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SLIDE 41

Lessons Learned/Avoid These Lessons Learned/Avoid These S S

 S

STEEP Arch ( TEEP Arch (Type III

Type III)

)

 S

SEVERE tortuosity EVERE tortuosity

 S

SHARP Entry Angle HARP Entry Angle

 S

SHARP Exit Angle HARP Exit Angle

 IN

INS SUFFICIENT UFFICIENT Landing Zone Landing Zone

 UN

UNS SATISFACTORY ATISFACTORY Collaterals Collaterals

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SLIDE 42

Lessons Learned/Avoid These Lessons Learned/Avoid These S S

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SLIDE 43

Technical Pearls Technical Pearls

 Remote Access for

Remote Access for Type III Arch Type III Arch

 Liberal Use of STIFF

Liberal Use of STIFF Buddy Wire Buddy Wire

 Know limitations of

Know limitations of DPD Devices DPD Devices

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SLIDE 44

Neuro Rescue Neuro Rescue Reality Bites! Reality Bites!

 Does Neuro Rescue Exist?

Does Neuro Rescue Exist?

– Intra-cranial Thrombolysis Intra-cranial Thrombolysis

  • Extrapolated Data from acute stroke lysis

Extrapolated Data from acute stroke lysis

  • Anecdotal cases

Anecdotal cases

  • Stroke during carotid stenting mostly

Stroke during carotid stenting mostly atheroembolism atheroembolism

  • Does risk benefit favor Thrombolysis?

Does risk benefit favor Thrombolysis?

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SLIDE 45

Neuro Rescue Neuro Rescue Reality Bites! Reality Bites!

 Neuro Does Rescue Exist !

Neuro Does Rescue Exist !

– Intra-cranial Thrombolysis Intra-cranial Thrombolysis

  • Some thrombus in symptomatic patients

Some thrombus in symptomatic patients

  • Secondary thrombus due to occlusion/stasis

Secondary thrombus due to occlusion/stasis

  • Mechanical jet effect of injection

Mechanical jet effect of injection

  • Allows clot extraction/distal migration

Allows clot extraction/distal migration

– Snare Snare – PTA PTA – MERCI Device MERCI Device

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SLIDE 46

Neuro Rescue Neuro Rescue Decision Time! Decision Time!

Gather data rapidly !

Gather data rapidly !

Risk benefit analysis

Risk benefit analysis

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SLIDE 47

Intra-cranial Thrombolysis Intra-cranial Thrombolysis

 Critical decision steps

Critical decision steps

– Is this a major deficit? Is this a major deficit? – Is there a branch vessel cut off? Is there a branch vessel cut off? – Can catheter be navigated to the target Can catheter be navigated to the target vessel? vessel? – Is the patient an acceptable candidate for Is the patient an acceptable candidate for Thrombolysis? Thrombolysis?

  • Systemic pressure

Systemic pressure

  • Anticoagulation status

Anticoagulation status

  • No major contra-indication

No major contra-indication

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SLIDE 48

Intra-cranial Neuro Intra-cranial Neuro Rescue Rescue

 Thrombolysis

Thrombolysis

 Wire manipulation across clot

Wire manipulation across clot

 Goose neck snare

Goose neck snare

 PTA

PTA

 MERCI concentric retrieval

MERCI concentric retrieval

 TCD

TCD

 Prayer

Prayer

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SLIDE 49

Intravenous Thrombolysis Intravenous Thrombolysis

 Only approved therapy in

Only approved therapy in USA USA

 Pro-UK not available

Pro-UK not available

 Community standard is

Community standard is Intracranial Lysis with Intracranial Lysis with Urokinase, tPA or rtPA Urokinase, tPA or rtPA

 IV Abciximab/Eptifibatide

IV Abciximab/Eptifibatide

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SLIDE 50

Intracranial Intracranial Thrombolysis Thrombolysis

The Rapid Micro Transit Catheter System, Envoy Guide & Transcend Wire (HIGASHIDA)

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SLIDE 51

Neuro Deficit Neuro Deficit

 Major strokes are rare after

Major strokes are rare after carefully executed carotid carefully executed carotid stenting with distal stenting with distal protection protection

 Minor strokes do happen

Minor strokes do happen

 Mostly atheroembolism

Mostly atheroembolism

 Thrombolysis remains the

Thrombolysis remains the mainstay of rescue mainstay of rescue

Qureshi et al., Stroke 33:1916-1919, 2002

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SLIDE 52

Conclusion Conclusion

 Technical Analysis helps in the selection of

Technical Analysis helps in the selection of

– Appropriate Cases Appropriate Cases – Equipment Equipment – Bailout techniques Bailout techniques

 Master The Anatomy You Can Master The

Master The Anatomy You Can Master The Technique! Technique!

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SLIDE 53

Carotid Mentoring Project Carotid Mentoring Project

www.carotidtraining.com

www.carotidtraining.com