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Recap Alife 2008
Walter de Back
Collegium Budapest Institute for Advanced Study
Recap Alife 2008 Walter de Back Collegium Budapest Institute for - - PowerPoint PPT Presentation
Recap Alife 2008 Walter de Back Collegium Budapest Institute for - - PowerPoint PPT Presentation
Recap Alife 2008 Walter de Back Collegium Budapest Institute for Advanced Study Prebiology: Error threshold Eigen, 1971 Hypercycles on a surface Boerlijst, Hogeweg 1991 Metabolic model Czaran, Szathmary 2000 Hypercycles vs. Metabolic model
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Hypercycles on a surface
Boerlijst, Hogeweg 1991
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Metabolic model
Czaran, Szathmary 2000
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Hypercycles vs. Metabolic model
n n i i i
x x M
/ 1
) ( = ∏
=
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Genotype - Phenotype
RNA folding
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Neutral networks
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RNA evolution
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RNA evolution
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Cellular Potts model
aka Glazier-Graner-Hogeweg model
- Two-scale cellular automata model
- Cell movement / Tissue development by Differential Adhesion
– Free energy bond Jij where i and j are the types of the cells – Sites changes state as to minimize free energy
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Gene regulation (Boolean) network
NK-network:
- N nodes
- K connections
Nodes have state 0 or 1 Nodes have logical rules (gates): e.g.
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Gene regulation (Boolean) network
Activation pattern (here: periodic) Sample network
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Evolution of reproductive restraint
Spatial self-structuring => Multi-level selection => Natural selection for less fit individuals
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