QuadroStarPRO Family - 577, 532, 940 & 980 nm Laser - - - PowerPoint PPT Presentation

QuadroStarPRO Family

• 577, 532, 940 & 980 nm Laser -

QSPRO 100 1116 EN 2

For more than 35 years, Asclepion has been operating on the medical laser

• market. As the company is based in Jena, famous through the world as the

global center of the optics industry since 1846, the company owes it success to the steady development of new technologies and the active collaboration with researchers from German universities and industries.

• More than 35 years experience in the aesthetic laser medicine and surgery
• Development, production, service & training center in Jena
• TOP100 of the most innovative medium-sized businesses in Germany

Technology „Made in Germany“

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DL5000 DLS5 ProYellow+ YellowStar BeautyStar QuadroStar QuadroStar+ Product Development Milestones of vascular laser systems

First argon laser for vascular treatments was introduced by Asclepion in 1984. The new QuadroStarPRO will be the first Table- Top-Laser for aesthetic laser treatment, available in four different wavelengths (yellow (577 nm), green (532 nm), 940 or 980 nm).

The new generation of vascular lasers

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Wavelength: 577 or 532 or 940 or 980nm Application: Dermatology Dermatology minor surgery and nail treatment Laser: HOPSL* (577, 532), class 4 Diode (940, 980), class 4 Power:

• Max. 5 Watt @ 577nm
• Max. 8 Watt @ 532nm
• Max. 30 Watt @ 940 or 980nm

Frequency: 0.5 to 100 Hz Operating modes: BASIC, EXPERT, BURST, VARIX, CW, SCAN Spot size: HOPSL: Standard 1.0 mm HOPSL: optional 0.5; 1.5; 2.8 mm Diode: for nail treatment 3.5 mm (for minor surgery dependent on fiber) Dimensions: 42 x 38 x 19 cm (B x T x H) Weight: < 12 Kg

* HOPSL = High-power Optically Pumped Semiconductor Laser All specifications are subject to change without notice.

Specifications

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Features

• Table-Top-Laser in an elegant design
• First laser available using yellow light
• Available as yellow, green or infrared laser
• HOPSL-Technology with high reliability
• High power and speed
• Homogeneous beam profile
• Scanner and integrated cooling system
• Foot switch to change Fluence & Speed

Clinical success

• 1984: With the introduction of Argon laser

for treatment of vascular lesions of retina, Asclepion took a leading role. With the KTP/LBO lasers BeautyStar, QuadroStar and QuadroStar+ Asclepion continues this

• tradition. Over 500 systems, only in

Germany show an exemplary success story.

• More than 30 years experience

Features

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Specifications

• Spot size:

1 mm, Area maximum 15 x 15 mm

• Scan density:

high

(100%; Spot by Spot; all shapes)

medium

(80%; distance 0.2mm; all shapes except point)

minimal

(60%; mild; distance 0.4mm; only big shapes)

• Shapes:

Applications

• mild treatment of large areas
• easy switch of handpiece and scanner
• automatic detection of scanner by device
• skin cooling integrated in scanner and device
• available for QuadroStarPRO YELLOW

Scanner with skin cooling

Scanner with skin cooling

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• handpieces with different spot sizes
• fibers for several indications (e.g. EVLT)
• special footswitch to adjust the fluence and / or repetition rate for an efficient workflow

Standard handpiece Handpieces for fibers Foot switch

Accessories

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Design – small, compact and light

• transportable Table-Top-System
• reduction in weight (>40%) and volume (>20%) along with the integration of the skin cooling*
• ergonomic tray for scanner and handpiece

* Compared to the previous model QuadroStar+

Design

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Technology – powerful, stable and efficient

• newest HOPSL-Technology (High-Power Optically Pumped Semiconductor Laser)
• newest skin cooling technology
• maximum power for vascular treatment
• high reliability
• foot switch to adjust the fluence & speed
• no running costs

* Compared to the previous model QuadroStar+

Technology

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Easy handling

• clear menu navigation
• clear and sharp display with touch sensitive keypad
• different background colors selectable

Mode Settings Application

BASIC Fluence, Frequency, (Ø Spot 1mm) Beginner EXPERT Spot size, fluence, pulse duration, frequency Expert BURST Spot size, fluence, pulse duration, frequency Difficult lesions VARIX Power, pulse duration, interval Varicose vein CW Power (total energy and pulse duration, incl. value set to zero) Surgery SCAN Fluence, pulse duration, interval, spot density, shapes Scanner TOOLS Pilot beam brightness, skin cooling, footswitch for setting Basics

Display

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QuadroStarPRO YELLOW QuadroStarPRO GREEN QuadroStarPRO 940 QuadroStarPRO 980

superficial vascular and benign pigmented lesions such as:

• telangiectasia, couperosis, spider nevus
• cherry angioma, venous lake
• small port wine stains, hemangioma, red leg veins
• sebaceous gland hyperplasia, warts, lentigines

endovenous treatment (EVLT)

• nail treatment
• vaporization of soft

tissue

Applications

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0.0001 0.001 0.01 0.1 1 10 100 1000 10000 100000

100 1000 10000

Wavelength [nm] Absorption Coefficient [cm-1]

4000 3000 2000 5000 500 400 300 200

Melanin Protein Water Scattering Desoxy-Hemoglobin Oxy-Hemoglobin

HIGH ABSORPTION in hemoglobin: The blood heats up and harms the inner vessel wall, this glued and thus closes the vessel. Yellow light is having the highest absorption. LOW ABSORPTION in water: Minimizes risks of side effects on light skin. HIGH ABSORPTION in melanin: Treatment

• f

benign pigmented lesions; NO treatment

• n

tanned skin or skin type V or VI; Careful use on skin type IV!

Selective absorption

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PDL Argon KTP HOPSL Diode Nd:YAG nm 510 514 532 577 800-980 1064 Hemangioma Spider naevus Venous lake Fine reticular veins Large reticular veins Telangiectasia Port wine stains

Penetration depth

QuadroStarPRO | vascular lesions

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• maximum of absorption in hemoglobin
• absorption in blood 40% higher
• less absorption in melanin
• less side effects
• less fluence needed
• better results by equal fluence

Source: Welch, Van Gemert: Optical-Thermal Response of Laser-Irradiated Tissue, p. 815, ISBN 0-306-44926-9 Blood absorption coefficient (mm-1)

 QuadroStarPROYELLOW is the best choice for vascular treatments

Wavelength (nm)

Absorption

Advantages 577nm (YELLOW) vs. 532nm (GREEN)

QuadroStarPRO | vascular lesions

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Indications 532 nm 577 nm DYE*

Telangiectasia ++ +++ +++ Spider nevus ++ +++ +++ Rosacea ++ +++ +++ Wart ++ +++ +++ Sebaceous gland hyperplasia ++ +++ +++ Lentigines + + + Small Hemangioma + ++ ++ Port wine stains + ++ +++ Small leg veins (superficial) + ++ ++

Side effects ++ +++ ++ Visibility ++ +++ +++ Reliability +++ +++ O Follow-up costs +++ +++ O System size +++ +++ O Weight +++ +++ O

+ good, ++ very good, +++ optimal * Dye lasers from other manufactures O poor

QuadroStarPRO | vascular lesions

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scanner tests after 5 days

On the left, large scale but superficial scabbing. 532 nm 31 J/cm2 11 ms scanner at max. density On the right, a significant vascular reduction with a minimum of scabbing. 577 nm 19 J/cm2 11 ms scanner at max. density

577 nm 532 nm

By courtesy of Dr. P. Wood, Proderma, Bad Homburg, Germany

QuadroStarPRO YELLOW | Port wine stains (PWS)

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scanner test after 3 weeks

right side: before treatment left side: significant better removal

• f PWS at the 577 nm

577 nm 532 nm

By courtesy of Dr. P. Wood, Proderma, Bad Homburg, Germany

QuadroStarPRO YELLOW | Port wine stains (PWS)

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before immediate reaction after 30 minutes

• ne month after

1 session

By courtesy of LoraDerm Clinic, Zagreb, Croatia

QuadroStarPRO YELLOW | Telangiectasia

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before and after 1 month, 1mm spot size, 14-16 J/cm2, shortest pulse

By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia

QuadroStarPRO YELLOW | Telangiectasia

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before

• ne month after

first session

• ne month after

second session

• ne month after

third session

By courtesy of LoraDerm Clinic, Zagreb, Croatia

QuadroStarPRO YELLOW | Hemangioma

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Parameters: Single scan circle 8mm, 15J/cm2, 32msec

By courtesy of Dr. Olga Bogomolets’ Institute of Dermatocosmetology, Oblast Mykolajiw, Ucraine

15 days after 2 session before

QuadroStarPRO YELLOW | Hemangioma

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Parameters: 18 J/cm2, Scanner 8mm, 32msec, Single scan

By courtesy of Dr. Olga Bogomolets’ Institute of Dermatocosmetology, Oblast Mykolajiw, Ucraine

15 days after 2 session before

QuadroStarPRO YELLOW | Hemangioma

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before and after 1 month, Scanner 80% coverage, 70% cooling, 20 J/cm², shortest pulse

By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia

QuadroStarPRO YELLOW | Post acne erythema

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before and after 1 month, Scanner 80% coverage, 70% cooling, 20 J/cm², shortest pulse + brush 14 J/cm² on spots defocused 5 cm

By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia

QuadroStarPRO YELLOW | Post acne erythema

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before and after 1 month, Scanner 80% coverage, 70% cooling, 22 J/cm², shortest pulse

By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia

QuadroStarPRO YELLOW | Post acne erythema

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before and after 1 month, 1 mm spot, 1 trace, 15 J/cm², shortest pulse

By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia

QuadroStarPRO YELLOW | Pigmented & vascular lesions

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before 30 days after 1 session 30 days after 2 sessions

By courtesy of LoraDerm Clinic, Zagreb, Croatia

QuadroStarPRO YELLOW | Melasma

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before 30 days after 1 session 30 days after 2 sessions

Parameters: 14 J/cm2, scanner 100%

By courtesy of LoraDerm Clinic, Zagreb, Croatia

QuadroStarPRO YELLOW | Melasma

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before and after 1 month, Scanner 80% coverage, 100% cooling, 18 J/cm², shortest pulse

By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia

QuadroStarPRO YELLOW | Melasma

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before and after 1 month, brush 12 J/cm² on spot defocused 5 cm, shortest pulse

By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia

QuadroStarPRO YELLOW | Lentigo

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before and after 1 month, brush 12 J/cm² on spot defocused 5 cm, shortest pulse before 30 days after 1 session

By courtesy of LoraDerm Clinic, Zagreb, Croatia

QuadroStarPRO YELLOW | Keratosis

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By courtesy of Dr. P. Wood, Proderma, Bad Homburg, Germany

before 3 weeks after 1 treatment immediate reaction: Spot 1mm, 12J/cm², 19ms

QuadroStarPRO YELLOW | Couperose/Rosacea

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By courtesy of Dr. P. Wood, Proderma, Bad Homburg, Germany

typical immediate reaction using the scanner: lighten up of the scanned area

QuadroStarPRO YELLOW | Couperose/Rosacea

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By courtesy of Dr. P. Wood, Proderma, Bad Homburg, Germany

before 5 days after 1 treatment 3 weeks later immediate reaction: Scanner 100%, 19 J/cm², 11 ms

QuadroStarPRO YELLOW | Telangiectasia

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By courtesy of Dr. P. Wood, Proderma, Bad Homburg, Germany

QuadroStarPRO YELLOW | Telangiectasia

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By courtesy of Dr. Abror Shermatov, Taschkent, Uzbekistan

QuadroStarPRO GREEN | Telangiectasia

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before after

By courtesy of Karolina Kykalova, Prag, Czech Republic

QuadroStarPRO GREEN | Telangiectasia

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before after

QuadroStarPRO GREEN | Naevus araneus

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Hemangioma Wart

CAVE: Children low Fluence!

Venous lake

By courtesy of Dr. Petrow, Bonn, Germany

QuadroStarPRO GREEN | vascular lesions

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before after

By courtesy of Karolina Kykalova, Prag, Czech Republic

Reddened hypertrophic scars

QuadroStarPRO GREEN | vascular lesions

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before after

By courtesy of Dr. Petrow, Bonn, Germany

Port wine stain (cheek)

QuadroStarPRO GREEN | vascular lesions

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Superficial pigmented lesions

• Solar Lentigo
• Freckle
• Hyper pigmentation after inflammation

Wart (seborrhoeic, viral, condyloma) Fibroma Adenoma sebaceous Milia

By courtesy of Karolina Kykalova, Prag, Czech Republic

QuadroStarPRO GREEN | more treatments

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QuadroStarPRO940 EndoVenous Laser Treatment

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Endovenous laser treatment (EVLT) During the procedure, a catheter bearing a laser fiber is inserted into the great saphenous vein or small saphenous vein through a small puncture. The catheter is then advanced under ultrasound guidance by means of a guide wire, which was inserted before. Under sonographic control the end of the catheter fixed with the laser fiber is positioned 1-2 cm in front of the opening in the Vena femoralis. Dilute local anesthetic is injected around and along the vein (perivascular infiltration). The catheter is withdrawn from the fiber in a way that the end of the fiber juts out of the catheter at least 10mm. The laser is activated whilst the catheter fixed to the laser fiber is slowly withdrawn, resulting in obliteration of the saphenous vein along its entire length. Laser effect Laser effect in the vein

QuadroStarPRO 940 | EVLT

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EndoSet This EndoSet serves for carrying

• ut

endovascular laser therapy and the treatment of varices. The treatment will be done with an EndoFiber NIRQ600 and the Insertion Set among local anesthesia.

QuadroStarPRO 940 | EVLT

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EndoFiber NIR Q600 (Fiber) with catheter Insertion Set

Focus on security:

• Catheter and fiber size are

concerted

• Fiber and catheter can be

coupled with each other, which guarantees a safe extraction of fiber and catheter

• Fiber is visible in ultrasound

through a metal ring at the end of the catheter, through that the treatment becomes more safe

• location of the end of the

fiber in the vessel is visible through the skin, thanks to pilot beam (additional control through ultrasound is necessary)

QuadroStarPRO 940 | EVLT

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By courtesy of Dr. Abror Shermatov, Taschkent, Uzbekistan

QuadroStarPRO 940 | EVLT

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By courtesy of Dr. Abror Shermatov, Taschkent, Uzbekistan

QuadroStarPRO 940 | EVLT

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QuadroStarPRO980 Nail treatment for Onychomycosis

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Onychomycosis: Fungal infections of the nails, especially of the toenails, are one of the most common fungal diseases. About five percent of the population is asking for a treatment, but the estimated number of people affected is approximately four to five times

• higher. Most of patients consider the changes and discoloration of the nails as unattractive

and maybe a little embarrassing, but they do not pay this too much heed. But the Onychomycosis is not a minor cosmetic problem only. If remains untreated, the infection can spread up and destroys at the end the nail cells completely, which leads to separation of the nail plate from nail bed.

Source: Deutsche Haut - und Allergiehilfe e.V./ Picture by courtesy of Dr. Koch, Harsefeld, Germany

QuadroStarPRO 980 | Nail treatment

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Laser treatment:

• Now there are several lasers with different parameters and treatment methods available and

used successfully, represent an additional option to the existing protracted therapies with high relapse rates.

• All together is the wavelength in the near infrared (870-1320nm, which ensures good

penetration) and the goal is to heat the nail.

• The study situation is currently not clear what the mechanism of action relates (reached nail

temperature is not enough to destroy fungus or spores), but the application studies and especially the practical experience in the treatment of many patients and their satisfaction demonstrate the usefulness of the treatment.

• Nevertheless, it should be noted in the informed consent discussion that the treatment

improves the visual appearance of the nail and recurrences are possible (including the famous The PinPointeTM FootLaserTM is approved by the FDA only for it: "is Indicated for use for the temporary increase enlarge of clear nail in patients with Onychomycosis").

QuadroStarPRO 980 | Nail treatment

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Laser treatment with the QuadroStarPRO980:

During laser treatment, the handpiece is moved quickly in serpentine pattern from left to right, from top to bottom etc. at the nail (including about 2mm skin surrounding the nail) until a remarkable warming can be felt – but no pain (otherwise stop treatment). It is the goal to keep an tolerable temperature as long as possible. To reach this, it is often the right way to apply low parameters – than the treatment time can be longer in most cases. The necessary treatment time depends on the size of the nail (at big toe about 1.5 – 2min.) and on how much the nail is discolored and thickened (less laser light penetrates the nail, especially thick nails should be reduced in respect to the thickness before).

QuadroStarPRO 980 | Nail treatment

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Big toe on the right (shooting with infrared camera)

Treatment time until 43°C is reached = 1min 20sec (small nail), no pain continuously scanned nail including nail edge of approx. 2mm before after 1 Min. 20 sec

QuadroStarPRO 980 | Nail treatment

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before 4 month after one treatment

Source: Asclepion Laser Technologies, Jena

QuadroStarPRO 980 | Nail treatment

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QuadroStarPRO980 Laser assisted lipolysis (LAL)

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Indications Reduction of local fat deposits, body contouring, slimming, skin tightening, collagen remodeling Treatment areas

• abdomen, hips
• areas where liposuction is not appropriate or with poor response (neck, chin, knee-cap, under bra – line etc.)
• areas with previous liposuction and persisting skin laxity

Laser Lipolysis / Laser assisted Liposuction (LAL)

• The delivery of laser energy to subcutaneous tissue by an optic fiber before/after liposuction or without

liposuction (at small areas).

• Lipolysis procedure involves an optical fiber, which sticks out from the tip of a microcannula, which is inserted

through a tiny skin incision into subcutaneous fat.

• The optical fiber is moved throughout the fat in a pattern resembling the spokes of a fan.

Tumescence anesthesia

• diluted local anesthesia is injected into the fat layer
• no general anesthetic necessary – significant less risk

Mechanism The laser melts unwanted fat efficiently by selectively targeting adipose fat and damages the dermal collagen by heat and causes shrinkage and ultimately neocollagenesis prompting reduction of lines and wrinkles and providing skin tightening.

QuadroStarPRO 980 | Laser assisted lipolysis

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Advantages laser technology Advantages QuadroStarPRO980

• smoother skin with less deformities compared to

liposuction

• faster healing with smaller incisions, less bruising, reduced

pain minimal blood loss and swelling

• cw – technology allows superior controlling of thermal

effect vs. competing high peak power pulsed laser; competing systems using short (200 µs) peak power pulses cause extreme temperatures in the tissue, leading to disruptive photomechanical and photo acoustic effects; these temperatures are high enough to cause unnecessary boiling and vaporization at the end of their tip

• Table top system with high power for shorter

treatment times

• different canulas and fibers available

(200, 300, 400 and 600 µm)

• special LipoSet with sterile fibers

(300 and 600 µm) and handpieces

• no consumables

QuadroStarPRO 980 | Laser assisted lipolysis

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Facilities and tools

• operations theatre (sterile area)
• Asclepion lipolysis bare fiber set L (300 µm and 600 µm fibers, handpieces, cannulas

Scalpel No. 11, 4x4 gauze, 20 cc syringe, 5 cc syringe 20 G spinal needle, 25 G needle, kidney pot, skin marker, bandage, drainage set, suction system Surgery procedures

• Preparation of QuadroStar+ with accessories
• Preparation tumescent solution, Lipolysis Set
• Lipolysis surgery

Pre-OP preparation

• Equipment preparation and sterilization
• Body examination
• Pre-OP medication
• Surgery line
• Picture records
• Body disinfection
• Anesthesia (tumescent therapy)

Post-OP care

• Picture records
• Massage

QuadroStarPRO 980 | Laser assisted lipolysis

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Preparation of LipoSet

• insert fiber into handpiece
• fiber has to jut out of cannula 5 - 7 mm in order to prevent

heating of cannula and thus skin burns, fiber must be fixed !! Surgery preparation

• QuadroStar 980: check function and select correct cw – mode
• connection of fibers
• safety goggles
• red aiming beam must be visible (brightness adjustment)

Parameter setting

• tight tissue: cw, 6 - 10 Watt, 300 µm fiber
• floppy tissue: cw, 4 - 8 Watt, 300 µm fiber

Experienced user may run high effective and high speed procedures by using 600 µm fiber, cw, 15 – 18 Watt.

QuadroStarPRO 980 | Laser assisted lipolysis

QSPRO 100 1116 EN 60

LipoSet

• 2 handpieces (300 µm and 600 µm)
• 1 fiber 300 µm/3m and 1 fiber 600 µm/3m
• 1 x 15 cm and 1 x 8 cm cannula for 600 µm, 1 x 5 cm and 1 x 10 cm

and 1 x 15 cm cannula for 300 µm Following information are examples – the necessary medication including quantity has to be decided by the physician !! Medications Midazolam (Dormicum ™, Benzodiazephrine) (oral) Tumescent solution (injection)

• 0,9% normal saline

1000 ml

• 2% lidocaine

50 ml

• Adrenaline 1: 100.000

1 ml

• 8,4 % sodium bicarbonate

12,5 ml

• 10 mg triamcinolone acetonide

1 ml

• total concentration 50/1064.5 = 0,093 % lidocaine
• tumescent injection volume is 150 – 250 ml cc per 10 x 10 cm area
• at incision points more volume is required
• less volume is required if liposuction is not performed
• volume decision to be taken by physician

QuadroStarPRO 980 | Laser assisted lipolysis

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Prepare tumescent as an anesthetic Use tumescent cannula

• r

spinal needle with 20 ml syringe or pump to inject solution into fat layer Spread tumescent evenly in a fan shape, use fan method according diagram below

QuadroStarPRO 980 | Laser assisted lipolysis

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Body examination and marking

• pinch test: examine location and thickness of fat layer
• incisions, operation area, anesthesia area, intensive area

QuadroStarPRO 980 | Laser assisted lipolysis

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Incision Fan method Surgery line Tumescent line

• quick forward and

backward move cannula creates channels and septum in fat tissue

• speed is around 10 cm

per second

QuadroStarPRO 980 | Laser assisted lipolysis

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Clinical results Lipolysis using a 980-nm Diode Laser: A Retrospective Analysis of 534 Procedures Jean Pascal Reynaud1, Martine Skibinski1, Benjamin Wassmer2, Philippe Rochon2, 3 and Serge Mordon3 Location

• No. procedures

(534)

• No. patients

(334) Total energy (J) Mean Total energy (J) SD Tumescent infiltration (ml) Mean Tumescent infiltration (ml) SD Hips 197 103 14,551 7,082 329 113 Abdomen 86 86 24,585 12,623 573 188 Thighs 61 32 10,427 5,581 264 82 Knees 61 34 8,140 4,401 112 56 Flanks 57 30 9,533 5,898 231 75 Buttocks 28 14 13,140 8,821 311 193 Chin 22 22 11,742 3,573 215 82 Arms 18 9 12,812 5,614 229 93 Back 4 4 21,913 12,374 675 106

QuadroStarPRO 980 | Laser assisted lipolysis

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Applied energy per area

QuadroStarPRO 980 | Laser assisted lipolysis

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Time table respective power applied QuadroStar power available: 30 Watt in tissue

2500 Joule 3000 Joule 3500 Joule 6 Watt 7 Min. 8 Min. 10 Min. 7 Watt 6 Min. 7 Min. 8 Min. 8 Watt 5 Min. 6 Min. 7 Min. 9 Watt 4.5 Min. 5.5 Min. 6.5 Min. 10 Watt 4 Min. 5 Min. 6 Min.

QuadroStarPRO 980 | Laser assisted lipolysis

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Patient satisfaction Lipolysis using a 980-nm Diode Laser: A Retrospective Analysis of 534 Procedures Jean Pascal Reynaud1, Martine Skibinski1, Benjamin Wassmer2, Philippe Rochon2, 3 and Serge Mordon3

QuadroStarPRO 980 | Laser assisted lipolysis

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By courtesy of Dr. Abror Shermatov, Taschkent, Uzbekistan

QuadroStarPRO 980 | Laser assisted lipolysis

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By courtesy of Dr. Abror Shermatov, Taschkent, Uzbekistan

QuadroStarPRO 980 | Laser assisted lipolysis

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before treatment 1 day after one treatment

Treatment results

before treatment 5 days after one treatment

By courtesy of Yann Renoulet, Dorsten, Germany

QuadroStarPRO 980 | Laser assisted lipolysis

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Treatment results

before treatment 1 month after one treatment

By courtesy of Yann Renoulet, Dorsten, Germany

QuadroStarPRO 980 | Laser assisted lipolysis

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VASCULAR LESIONS (532 & 577 nm)

Treatment of superficial vascular lesions with the KTP 532-nm laser: experience with 647 patients. Becher GL, Cameron H, Moseley H. Lasers Med Sci. 2014 Jan;29(1):267-71. doi: 10.1007/s10103-013-1330-5. Epub 2013 Apr 30. Treatment of superficial cutaneous vascular lesions: experience with the KTP 532 nm laser Clark C, Cameron H, Moseley H, Ferguson J, Ibbotson SH. Photobiology Unit, Department of Dermatology, Ninewells Hospital Medical School, University of Dundee, DD1 9SY, UK. Lasers Med Sci. 2004;19(1):1-5. Comparison of the 532-nm KTP and 1064-nm Nd:YAG lasers for the treatment of cherry angiomas Pancar GS1, Aydin F, Senturk N, Bek Y, Canturk MT, Turanli AY. Department of Dermatology, Ondokuz Mayis University School of Medicine, Samsun, Turkey. J Cosmet Laser Ther. 2011 Aug;13(4):138-41. doi: 10.3109/14764172.2011.594058. Epub 2011 Acne rosacea: effectiveness of 532 nm laser on the cosmetic appearance of the skin Maxwell EL1, Ellis DA, Manis H. Art of Facial Surgery, Facial Plastic Reconstructive Surgery, Toronto, ON lindamaxwell22@hotmail.com. J Otolaryngol Head Neck Surg. 2010 Jun;39(3):292-6. Treatment of spider leg veins with the KTP (532 nm) laser--a prospective study. Spendel S, Prandl EC, Schintler MV, Siegl A, Wittgruber G, Hellbom B, Rappl T, Berghold A, Scharnagl E. Lasers Surg Med. 2002;31(3):194-201. The utilization of a new yellow light laser (578 nm) for the treatment of class I red telangiectasia of the lower extremities. Sadick NS, Weiss R. Dermatol Surg. 2002 Jan;28(1):21-5. Copper bromide laser treatment of facial telangiectasia: results of patients treated over five years. McCoy SE. Lasers Surg Med. 1997;21(4):329-40. An evaluation of the copper-bromide laser for treating telangiectasia. McCoy S., Hanna M, Anderson P, McLennan G, Repacholi M. Dermatol Surg. 1996 Jun;22(6):551-7.

Bibliography | QuadroStarPRO

QSPRO 100 1116 EN 73

PIGMENTED LESIONS (532 & 577 nm)

Clinicopathologic efficacy of copper bromide plus/yellow laser (578 nm with 511 nm) for treatment of melasma in Asian patients. Lee HI, Lim YY, Kim BJ, Kim MN, Min HJ, Hwang JH, Song KY. Dermatol Surg. 2010 Jun;36(6):885-93. doi: 10.1111/j.1524-4725.2010.01564.x. Epub 2010 May 7. Split treatment of photodamaged skin with KTP 532 nm laser with 10 mm handpiece versus IPL: a cheek-to-cheek comparison. Butler EG 2nd1, McClellan SD, Ross EV. Lasers Surg Med. 2006 Feb;38(2):124-8.

OTHER LESIONS (532 & 577 nm)

Two-year follow-up results of copper bromide laser treatment of striae. Longo L, Postiglione MG, Marangoni O, Melato M. J Clin Laser Med Surg. 2003 Jun;21(3):157-60. Recalcitrant viral warts: results of treatment with the KTP laser. Gooptu C, James MP. Clin Exp Dermatol. 1999 Mar;24(2):60-3.

ENDOVASCULAR LASERTHERAPY (940 nm)

Endovenous laser treatment of saphenous veins: is there clinical difference using different endovenous laser wavelenghts? Cavallini A. Int Angiol. 2015 Feb;34(1):1-8. Epub 2014 Jun 13. Endovenous laser treatment (EVLT) for the saphenous reflux and varicose veins: a follow-up study. Firouznia K, Ghanaati H, Hedayati M, Shakiba M, Jalali AH, Mirsharifi R, Dargahi A. J Med Imaging Radiat Oncol. 2013 Feb;57(1):15-20. doi: 10.1111/j.1754-9485.2012.02457.x. Epub 2012 Oct 9.

Bibliography | QuadroStarPRO

QSPRO 100 1116 EN 74

NAIL TREATMENT (980 nm)

Laser therapy of onychomycosis. Nenoff P1, Grunewald S, Paasch U. J Dtsch Dermatol Ges. 2014 Jan;12(1):33-8. doi: 10.1111/ddg.12251. Epub 2013 Nov 18. Antifungal efficacy of lasers against dermatophytes and yeasts in vitro. Paasch U, Mock A, Grunewald S, Bodendorf MO, Kendler M, Seitz AT, Simon JC, Nenoff P. Int J Hyperthermia. 2013 Sep;29(6):544-50. Heat profiles of laser-irradiated nails. Paasch U, Nenoff P, Seitz AT, Wagner JA, Kendler M, Simon JC, Grunewald S. J Biomed Op. 2014 Jan;19(1):18001.

VAPORIZATION OF SOFT TISSUE (980 nm)

Evaluation of safety and efficacy of 980-nm diode laser-assisted lipolysis versus traditional liposuction for submental rejuvenation: A randomized clinical trial. Valizadeh N, Jalaly NY, Zarghampour M, Barikbin B, Haghighatkhah HR. J Cosmet Laser Ther. 2015 Jul 3:1-6. [Epub ahead of print] Laser assisted lipolysis for neck and submental remodeling in Rohrich type I to III aging neck: a prospective study in 30 patients. Leclère FM, Moreno-Moraga J, Alcolea JM, Casoli V, Mordon SR, Vogt PM, Trelles MA. J Cosmet Laser Ther. 2014 Dec;16(6):284-9. doi: 10.3109/14764172.2014.946053. Epub 2014 Sep 19. Results of Laser assisted Lipolysis using a 980 nm diode Laser Yann Renoulet, MD. 2010. Plastic and Reconstructive Surgery Center, Center for Lasertherapy, Elisabeth Krankenhaus Recklinghausen,Recklinghausen, Germany Safety of Laser assisted Lipolysis using a 980 nm diode Laser Yann Renoulet, MD. 2010. Plastic and Reconstructive Surgery Center, Center for Lasertherapy, Elisabeth Krankenhaus Recklinghausen, Recklinghausen, Germany

Bibliography | QuadroStarPRO

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