Pharmaceutical chemistry terminology Pharmacy It is concerned - - PowerPoint PPT Presentation

Pharmaceutical chemistry terminology

Pharmacy

 It is concerned with the collection, preparation and standardization

• f drugs

 In other words it covers the cultivation of medicinal plants, synthesis

• f compounds of medicinal value,chemical analysis and testing of

the compound Pharmacology

 It is concerned with the effect of drugs on livibg animals l,organs or

tissues

 Actually the word pharmacology is a Greek word,’pharmaca’

means drug ‘logos’ means treatise

 Pharmacology includes various terms like toxicology,posology and

therapeutic

Pharmacodynamics

 It deals with the response of living organisms to cheimcal stimules in

the absence of disease

 This tells about possible use of a particular therapeutic agent in the

treatment of disease in human Pharmacophore

 It is a functional group whose presence is responsible for the

medicinal activity of a drug

 Removal of pharmacophore from the molecule of the drug

completely destroys the medicinal value

 Some of the functional groups are –R,-OH,-OR,-CHO,-X etc

Pharmacokinetics

 It is the study of the action of drugs in the body

ADM

 ADMEE means absorption, distribution, metabolism and excretion  ADME is formed from the intial letters of pharmacokinetics and

pharmacology for absorption, distribution, metabolism and excretion

 ADME influence the drug level and kinetics of drug exposure to the

tissues

Receptor

 In bio chemistry a receptor is a protein molecule embedded in

either the plasma membrane or the cytoplasm of cell

 A molecule which binds or attach to a receptor is called ligand  The ligands are also called neuro transmisster