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lanosterol, mammalian precursor for all steriod hormones cholesterol - - PowerPoint PPT Presentation
lanosterol, mammalian precursor for all steriod hormones cholesterol - - PowerPoint PPT Presentation
lanosterol, mammalian precursor for all steriod hormones cholesterol How a noncyclic alkene is converted to the steriod ring skeleton squalene squalene epoxide rearrangement, followed by 1,2-shifts, then elimination of an H+ and loss of CH 3 s
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rearrangement, followed by 1,2-shifts, then elimination
- f an H+ and loss of CH3s as CO2 yields lanosterol
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Benz[a]pyrene diol epoxides: potent mutagens
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Look at 1/2 of the DNA double helix:
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