lanosterol, mammalian precursor for all steriod hormones cholesterol - PowerPoint PPT Presentation

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lanosterol, mammalian precursor for all steriod hormones cholesterol How a noncyclic alkene is converted to the steriod ring skeleton squalene squalene epoxide rearrangement, followed by 1,2-shifts, then elimination of an H+ and loss of CH 3 s

lanosterol, mammalian precursor for all steriod hormones cholesterol
How a noncyclic alkene is converted to the steriod ring skeleton squalene squalene epoxide
rearrangement, followed by 1,2-shifts, then elimination of an H+ and loss of CH 3 s as CO 2 yields lanosterol
Benz[a]pyrene diol epoxides: potent mutagens
Look at 1/2 of the DNA double helix:

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