Innovations In Neuromodulation: Venture Capital Panel June 6, 2015 - PowerPoint PPT Presentation

Innovations In Neuromodulation: Venture Capital Panel June 6, 2015 Tony Borowicz VP, Business Development

Greatbatch As A Core Partner Batteries | Capacitors | Catheters | Stimulation Leads | Feedthroughs Device Enclosures & Cases | Device Headers | Device Assembly Advanced Coatings | Introducers | Orthopaedic Trays, Cases & Implants Header Enclosure Battery Feedthrough Stimulation Leads

Who We Serve 3

How We Partner Segment Offering Develops and commercializes high-value neural interface technology, components and systems for neuroscience and clinical applications Develops and manufactures complete medical devices, including active implantable medical devices for neuromodulation Designs and develops medical device technologies and system level platforms Designs and manufacturers medical devices and discrete technologies for CRM, neuromodulation, vascular, orthopaedic, and portable medical applications Makes strategic investments in markets, products, or GB Ventures technologies aligned with Greatbatch business categories or adjacent growth opportunities

R&D Neural Interface Develops advanced technologies and devices for Neuroscience & Neurostimulation research markets Basic science & Applied science & Clinical translational technology studies technology studies studies Thin-film electrodes NeuroNexus powers the R&D leading to next-generation neurostimulation markets, indications, and products

Device Development & Manufacturing Proven Fully Integrated Turn-key Medical Development Manufacturing Quality System Manufacturing Platform Facility  Fast prototyping  Sensing  Class 7 & 8 clean  ISO 13485:2003 areas certified (BSI)  Full product design &  Stimulation  Complete IPG  FDA 21 CFR Part 820 development  Communication  Testing & verification assembly and registered  Battery recharge  Packaging &  Low & medium  Impedance measure sterilization volume manufacturing  FW download  IDE, PMA, & CE Mark  Other modules documentation CCC is dedicated to the development & manufacturing of complete real-time medical systems including active implantable medical devices

System Platform R&D Design & development of complete neurostimulation system platforms  IPGs  Leads  Programmers  Software  Accessories QiG Group empowers the creative design, development and speed to market of new medical devices in strategic markets

Design & Manufacturing  Component, value-added-assembly & full system manufacturing  FDA Registered Facility / Regulatory: ISO13485:2003, CMDCAS, AIMD & MDD Greatbatch Medical is committed to the design and manufacture of critical technologies that enhance the reliability and performance of medical devices

GB Ventures Strategic Investments Minority Equity Strategic Investment Philosophy  $2 – 5M targeted investments  3 – 5 targeted deals per year  Typically board observer seat  < 20% ownership equity positions nor maintain controlling interest Cardiac Neuromodulation Orthopaedics Vascular Portable Medical GB Ventures targets strategic investments in markets, products or technologies aligned with Greatbatch business categories or adjacent growth opportunities

GB Ventures How We Invest Creating a ‘ Win – Win’ Partnership Investment Return Cash Equity Royalty, Additional Equity, Innovations & IP Alternate Fields of Use Product Development Services NRE Funding Manufacturing Capabilities Exclusive Long Term Agreement Commercialization Avenues Exclusive Distribution Agreement

Positioned for Neurostimulation Partnerships Medical Device Components Early Stage Innovation Medical Device Systems   Equity investments Leads  Platform system reduces   time and risk to market Research Batteries  Other Neurostimulation   Prototyping Feed throughs indications   Component manufacturing FDA experience for clinical trials  Quality Systems GB Ventures

Our Story  One-stop shop for long-term strategic partnerships from early stage investments through commercialization  Multi-faceted mechanisms supporting: › Investments › Research › Technology development › Clinical trials › Manufacturing  History as world-class component supplier  Next generation device development  High volume manufacturing Unique Partnership Opportunity in the Field of Neuromodulation. Leverage our Capital, Technologies, Components, Platforms & Manufacturing

Thank you! Innovations In Neuromodulation: Venture Capital Panel June 6, 2015 Tony Borowicz VP, Business Development