I Do Clinical/Health Services What is the Alberta SPOR SUPPORT Unit? - PDF document

1/30/2017 Clinical Research Seminar Series Clinical Research Seminar Series January 26, 2017 January 26, 2017 SPOR Platform Discussion SPOR Platform Discussion Presented by: Drs. Finlay McAlister, Ross Tsuyuki, Lisa Hartling Three Alberta Strategy for Patient-Oriented Research (SPOR) Unit Platform leads from the Data (Dr. Finlay McAlister), Consultation & Research Services (Dr. Ross Tsuyuki), and Knowledge Translation Platforms (Dr. Lisa Hartling) will be presenting on what SPOR can do for clinical and health services researchers at the University of Alberta. Questions? Dr. Jill Byrne (Director, Clinical Research; FoMD) jill.byrne@ualberta.ca I Do Clinical/Health Services What is the Alberta SPOR SUPPORT Unit? Research, What Can • The ABSPORU is a five year $48 million federal-provincial ABSPORU Do For Me? partnership between AIHS and CIHR (2015-2020). Finlay A. McAlister, MD MSc On behalf of the ABSPORU Data Platform • We are part of a network of SPOR (Strategy for Ross T. Tsuyuki, PharmD MSc Patient-Oriented Research) SUPPORT (Support for On behalf of the ABSPORU Consultation and Research People and Patient-Oriented Research and Trials) Services Platform Unit across Canada. Lisa Hartling, PhD On behalf of the ABSPORU KT Platform 1

1/30/2017 ABSPORU – Infrastructure, but not operating Our Vision and Goal funds SPOR Provincial Support Units • Vision: Advance knowledge to improve patient health and health care. • Goal: Increase the quantity and quality of patient- oriented health research. 3 Chronic Disease Management Networks Alberta SPOR SUPPORT Unit Our Partners • Five platforms provide direct • The Alberta SPOR SUPPORT Unit partners with: services to researchers. – Alberta Health – Alberta Innovates – Health Solutions • Two platforms, Career – Alberta Health Services Development and Pragmatic – Athabasca University Clinical Trials, help build capacity in – University of Alberta Alberta’s research community by – University of Calgary providing a number of career – University of Lethbridge development and training opportunities. 2

1/30/2017 Alberta SPOR SUPPORT Unit Patients Benefit What does the ABSPORU Data Platform Intake Projects Supports offer? Patient- Adequately System resourced oriented 1 Change 2 • Support Services for Research Involving secondary Feasible 3 analysis of existing Large Datasets (especially, but not 4 limited to, administrative data) : 5 Projects selected – Research Design: methods, sample size, biostatistical plan, 6 support letters for grants, assistance with Researcher 7 Evaluation Agreements 8 – Data Management: data extraction, linkage, and cleaning 9 10 – Biostatistics: consultations and/or analy ses (if necessary, Resources Assigned 0% 50% 100% and in conjunction with Methods Support platform ) Resources Reassigned – Training (in conjunction with Training and Methods Support platforms ): emphasis on practicums, theses. Patient Engagement Consultation Data Methods Implementation Pragmatic & research research & Platforms & support & clinical trials services Services development Knowledge Career development in methods Translation & health services research 10 But Not ADT • Incubation/development of research questions Lab DI* Pharmaceutical Claims DAD and choice of study methods (primary vs. secondary data sources, RCT vs. cohort, etc) Outpatient Vital Statistics AHSDRR Clinic and Registry ED Visits • Support for primary data collection studies (NACRS, EDIS, REDIS) SES EMS* (Census Data) Physician •  Consultation and Research Services Platform Claims** http://insite.albertahealthservices.ca/assets/drs/tms-drs-ahsdrr-data-asset-inventory.pdf 11 37 databases as of October 2016 3

1/30/2017 The AHSDRR and where does 25 pages of info on datasets in the ABSPORU Data Platform fit? AHSDRR ALBERTA HEALTH • Inpatient - Discharge Abstract Database ( DAD ) • Family & Population Health – Available from: April 1, 2002 to current • Primary Health Care – Data refresh occurrence: Monthly ALBERTA HEALTH • Strategic Services SERVICES • Health Benefits and Compliance • Laboratory (Lab R1 and R1.1) • Mental Health & Addictions • Health Work Force • Cancer • Senior Services & Continuing – Available from: LabFusion: Jan 1, 2009 to current. Meditech: Jan 1, 2009 to current. • Seniors’ Health Care AHSDRR Millennium: Apr 1, 2012 to current. Sunquest: Apr 1, 2012 to current. • Primary Care • Research – Data refresh occurrence: Daily (with up to 8 days latency) • Public Health • Cardiology • Emergency Care • Advanced Analytics • Provincial Registry • Critical Care • Methods and Models • Surgery – Available from: Fiscal Year End 1994 – March 31, 2014 • Information Products/Studies • Bone & Joint EXTERNAL – Data refresh occurrence: Annually • Zones • Respiratory • Academic Institutions • NACRS • Research • Other Ministries – AHS RPI Available from: Arpil 1, 2010 to current AB SPOR – (specifically the Data refresh occurrence: Monthly • HQCA SUPPORT Research Data Facilitation Platform 13 Group) How to access services: www.absporu.ca Resources • Infrastructure support: – DIMR: biostatisticians and data managers/analysts – Computers, stats software, CPE funds • NOT OPERATIONAL FUNDS, NOR MATCHING FUNDS 15 4

1/30/2017 Process Case Resource Request Manager Review allocated in AI Questions Eligibility Criteria Letter of Support Selection Criteria Scholarship Research Question Refinement Project Support Data Platform Activities as of Criteria fall, 2016 • Eligibility Criteria • Research – AB/NWT PI, AB setting and – ER, card, pulm, nephro, family med, surgery • Data Management: 66/75 requests for cohorts completed investigator – HREB approval thus far (median time to completion 4 weeks) • For obtaining data – ICU, pharmacy, CV surgery, community health, ER, geriatrics, pediatrics, surgery, card, GIM, bone and joint • Data linkage: 20/24 external cohorts linked • Selection Criteria • Statistical Analysis: 27/30 cohorts analyzed – Patient-oriented or health system-oriented outcomes – GIM, card, ICU, bone and joint, community health, surgery – End-user engagement – one collaborative project with Ontario ICES data (HOMR score) – Feasibility – Likelihood of Significant Patient/System Impact 20 5

1/30/2017 Who has requested assistance? • 47 uni researchers • 14 students (masters, doctoral) • 5 post-docs • 47 health system practitioners (includes SCNs) • Overall: 45% UofA, 44% UofC, 11% AHS Application form Application form – Contact information – Study information 6

1/30/2017 Application form Application form – Study information Application form Application form – Required support from ABSPORU – Platform services 7

1/30/2017 Application form Application form Consultation & Research Services Platform absporu.ca Application form Prospective Studies Primary Data Collection Qualitative and Quantitative Design/Method Data Management Biostatistics - Development of - Development of - Research question case report forms analytical plans refinement - Database - Sample size - Project design development and - Method calculation maintenance consultations - Statistical analysis - Randomization - Clinical Event - Grant review - Quality assurance Adjudication Contact: yazid.alhamarneh@ualberta.ca 8

1/30/2017 CRS activities to date Portal applications • Launched November 2015 • Applicants are students, residents, postdocs, nurses, clinicians, professors • 24 pre-consults – 10 led to portal applications – 14 active pre-consults • 33% were early career researchers • Services requested – 93 % Design/Methods • 7% were new to Alberta – 21% Analytical plan preparation – 7% Sample size calculation Application sources Services requested 2 2 7 5 2 19 2 60 2 28 5 42 30 12 51 35 51 47 30 Design/Method Statistical analysis Database creation and maintenance Analytical plan U of A U of C AHS U of L PCN Covenant Health QA CRF Sample size calculation Randomization Edmonton Seniors Centre Institute for Health Economics Tom Baker Cancer Centre Clinical event adjudication Qualitative 9

1/30/2017 Application form Knowledge Translation (KT) Platform Our long-term vision for Alberta SPOR KT Platform is increased capacity in the Alberta health care research environment for effective, evidence-based work in KT and integration of KT into patient-oriented research (POR) activities. Knowledge Translation KT Platform: Scope • A dynamic and iterative process that includes the synthesis , • We offer consultation, support and training in: dissemination , exchange and ethically-sound application of – Knowledge synthesis (KS) knowledge to improve the health of Canadians, provide more effective health services and products and strengthen the – Knowledge translation (KT) healthcare system. • This process takes place within a complex system of interactions – Implementation science (IS) between researchers and knowledge users which may vary in • We work with researchers across Alberta who intensity, complexity and level of engagement depending on the nature of the research and the findings as well as the needs of the require assistance with their patient-oriented particular knowledge user (Graham, 2010). research projects. CIHR definition (www.cihr-irsc.gc.ca/e/29418.html) 10