SLIDE 1
M . E L I Z A B E T H M . Y O U N G E R C R N P , P H . D A S S I S T A N T P R O F E S S O R , P E D I A T R I C S J O H N S H O P K I N S U N I V E R S I T Y S C H O O L O F M E D I C I N E B A L T I M O R E , M A R Y L A N D
Gastrointestinal Disease in CGD M . E L I Z A B E T H M . Y O U N - - PowerPoint PPT Presentation
Gastrointestinal Disease in CGD M . E L I Z A B E T H M . Y O U N - - PowerPoint PPT Presentation
Gastrointestinal Disease in CGD M . E L I Z A B E T H M . Y O U N G E R C R N P , P H . D A S S I S T A N T P R O F E S S O R , P E D I A T R I C S J O H N S H O P K I N S U N I V E R S I T Y S C H O O L O F M E D I C I N E B A L T I
SLIDE 2
SLIDE 3
Possible Symptoms
Failure to thrive or falling off of the growth curve Malaise and fatigue Abdominal pain Loose or frequent stools OR Bloating associated with infrequent stools Decreased appetite
SLIDE 4
Characteristics
Strictures (narrowing) in the intestines Fistulas Obstruction secondary to granulomas Inflammatory process, not infectious Decreased protein or albumin, measured in the
blood
More lesions in lower colon (rectum and anus) but
lesions are found throughout the GI tract
SLIDE 5
Diagnosis
Endoscopy (upper and lower) is the Gold
STANDARD for diagnosis
SLIDE 6
“Take home” for parents
Be aware of the prevalence of GI disease associated
with CGD
Don’t discount subtle signs:
Fatigue Changes in bowel habits Changes in appetite Abdominal pain