Evolution of medical imaging -Role of imaging in informing clinical - - PowerPoint PPT Presentation

▶

Feb 20, 2023 36 likes •120 views

Evolution of medical imaging -Role of imaging in informing clinical decisions: liver cancer Ken Shirabe Gunma University, Japan My G My Gran randfat father er Ra Raisu isuke Shi Shirabe abe was was a s a survi rvivor or

SLIDE 1

Evolution of medical imaging

Role of imaging in informing

clinical decisions: liver cancer Ken Shirabe

Gunma University, Japan

SLIDE 2

My G My Gran randfat father er “Ra Raisu isuke Shi Shirabe abe” ” was was a s a survi rvivor

after ter Ato Atomic B ic Bomb

mb in N

in Naga agasaki aki

More than 850 of medical students, staffs, and patients died . 414 of 580 students (71%) died. Nagasaki Medical College was completely destroyed.

SLIDE 3

Hepatocellular carcinoma (HCC) Hepatitis B virus (Japan Liver Cancer Society: Kanzo 41; 799-811, 2000.) Hepatitis C virus (HCV) (79%) HBV positive (11%) HBV and HCV positive (1%) nonBnonC (11%) Number of suffers: more than 700, 000 people in the world per year. Incidence of HCC High Intermediate Low Incidence of HBs Ag High Intermediate Low

HCC and hepatitis virus: world distribution

SLIDE 4

HCV HBV Alcohol Fatty liver Cholestasis

Liver Cirrhosis

Liver cancer (Hepatocellular carcinoma: HCC)

ften occurs in injured liver.

・Liver is vital organ. ・Functional limitation for resection in injured liver ・Massive bleeding may occur during liver resection

For safe hepatectomy, To simulate precise simulation To reduce blood loss are essential.

SLIDE 5

Simulation before hepatic resection, using 3D imaging

Estimated resection volume, and residual liver volume after hepatectomy, blood vessels, which would be cut during resection can be simulated.

SLIDE 6

3D imaging DICOM data Forming of 3D model, using 3D printer

Preoperative simulation of liver surgery, using Bio-Texture Modeling

Joint research with Prof. Maki Sugimoto, Teikyo University

Left lateral segment graft （Full-length）

LHV GV 277g GRWR 4.5% PV

SLIDE 7

The making of 3D imaging

SLIDE 8

85-90 (n=162) 97-03 (n=213) 91-96 (n=250) 09-14 (n=157) 04-08 (n=346)

Changes in blood loss, transfusion rates and postoperative complication

200 400 600 800 1000 1200 1400 1600

Blood loss (ml)

20 40 50

Blood transfusion rates (％)

1130 130 1500 500 770 770 48 52 14 555 55 8 656 656 275 275

15-18 (n=182)

10 20 30 40 50 Complication rates (%)

91-96 (n=250) 97-03 (n=213) 04-08 (n=346) 09-14 (n=157)

Mortality Liver failure Bile leakage Ascites