IFIC TRAINING COURSE DETECTORS AND ACCELERATORS DETECTORS AND ACCELERATORS APPLIED TO MEDICINE José Bernabéu José Bernabéu IFIC-Valencia IFIMED Project Leader PARTNER-CERN 16 October 2008
IFIC TRAINING COURSE DETECTORS AND ACCELERATORS APPLIED TO MEDICINE • IFIC is participating in the training activity of PARTNER IFIC i i i i i h i i i i f PARTNER students offering a one week course on “Detectors and Accelerators for Medicine”. • The course will be also open to other European graduate students interested in Medical Physics. • The PARTNER course will take place at the beginning of June 2009 at IFIC- Valencia, just before the planned IFIMED’09 W IFIMED’09 Workshop oriented to potential users of the k h i t d t t ti l f th Facility. • The course will consist of five different topics developed in four hours each, plus six hours for tutorial sessions.
IFIC TRAINING COURSE The subjects covered in this course are: � Monte Carlo and Simulation of Physical Monte Carlo and Sim lation of Ph sical Processes (MSP) � Information and Communication Techniques: GRID environment (ICT) � Accelerators for Medicine (AM) � Image Science (IS) Image Science (IS) � Radiation Detectors (RD)
IFIC TRAINING COURSE Monday Monday Tuesday Tuesday Wednesday Wednesday Thursday Thursday Friday Friday 09:30 RD RD RD RD 10:30 break 11:00 AM AM AM AM 12:00 IS IS IS IS Lunch time MSP MSP MSP MSP MSP MSP MSP MSP 15:00 15:00 16:00 break 16:30 ICT ICT ICT ICT 17:30 Tutorial Tutorial Tutorial Tutorial MSP:Monte Carlo and Simulation of Physical Processes: (J.Navarro (IFIC) / J. Salt (IFIC)). ICT: Information and Communication Techniques: GRID environment: (H.F. Hoffmann (CERN) /G. Amoros (IFIC)/….). (H.F. Hoffmann (CERN) /G. Amoros (IFIC)/….). AM: Accelerators for Medicine: (U. Amaldi (TERA) /.A. Faus-Golfe (IFIC)). RD: Radiation Detectors: (N. Clinthorne (Michigan University / C. Lacasta (IFIC)). IS: Image Science: (M.Defrise (Vrije Universiteit) / M. Rafecas (IFIC)).
IFIC TRAINING COURSE Monte Carlo And Simulation of Monte Carlo And Simulation of Physical Processes Objectives: These lectures aim at providing the essential ideas concerning the Monte Carlo method and simulation techniques for physical processes. Some applications will be done using the GEANT simulation code. The will be done using the GEANT simulation code. The participants will learn the rudiments of such a powerful tool .
IFIC TRAINING COURSE Lecture 1 : THE MONTE CARLO METHOD THE MONTE CARLO METHOD (2 hours) 1.1. Basic concepts of statistics. Random variables. p Distribution functions. Expectation values. The central limit theorem. 1.2. Generation of random numbers. The uniform distribution. The method of change of variables. The acceptation-rejection method. acceptat o eject o et od 1.3. Monte Carlo quadrature. Crude Monte Carlo Importance sampling method Monte Carlo. Importance sampling method. Markov chains. Metropolis algorithm. Simulation of a tipical Linear Accelerator used for Radiaton Therapy
IFIC TRAINING COURSE Lecture 2: SIMULATION OF PHYSICAL PROCESSES (2 hours) 2.1. Radiation Transport. Random Paths. Modelization of events 2.2. Simulating different types of radiation. Electrons. Protons. Heavy particles, Electromagnetic radiation. P H i l El i di i 2 3 Simulation Codes GEANT 2.3. Simulation Codes. GEANT A superficial brachytherapy device and the resulting A superficial brachytherapy device and the resulting dose distribution, simulated with Geant4 .
IFIC TRAINING COURSE Information and Communication Information and Communication Techniques - I • e-Science and GRID technologies S i d GRID t h l i The challenges of the Modern Science: high CPU consuming and processing of large amount of DATA High Performance Computing processing of large amount of DATA. High-Performance Computing and High-Throughput Computing. • Introduction to the GRID: - GRID actors : Computing Element (CE), Worker Nodes (WN), Storage Element (SE), Workload Management System (WMS), File Catalogs, Information Services, Virtual (WMS) Fil C t l I f ti S i Vi t l Organization (VO), User Interfaces. - How to use the GRID : Authenticity and authorization, y , Job Management, monitoring, Data Management, how to find the resources, Job Description Language.
IFIC TRAINING COURSE Information and Communication Information and Communication Techniques – II • GRID and Medical Physics: y Applications. State of the art. – The language and repositories in Medical Physics: Introduction to the metadata, security and authorization in the Introduction to the metadata security and authorization in the medical physics applications. The DICOM standards and catalogs as data searching tools. Example of the WISDOM project: malaria avian flue project: malaria, avian flue. – Simulations within the GRID: History of the benefits and results of GEANT4 on the GRID: GATE. First applications to Hadron-therapy Hadron-therapy.
IFIC TRAINING COURSE Accelerators for Medicine Accelerators for Medicine Accelerators for Medicine Accelerators for Medicine This course will provided an introduction of the most used Accelerators in Accelerators in Medicine. Medicine. We will We will introduce the concept, introduce the concept, general description of the most important parameters for linear accelerators, cyclotrons and synchrotrons. We will introduce the special case of the use of these accelerators in p Medicine, and more specifically in Hadrontherapy. Finally we will review the novel concepts in the field of Medical Accelerators. The course will be organized in four lectures of one hour each, complemented with tutorials where we could compare the different different kinds kinds of of Medical Medical Accelerators Accelerators described described in in the the lectures. The aim will be the understanding of their applications and limitations. 10
IFIC TRAINING COURSE Accelerators for Medicine Accelerators for Medicine f 1. Short introduction to Accelerator Techniques and related Instrumentation 2. 2 A Accelerators for Medical Applications: l t f M di l A li ti 1. Linear Accelerators 2. Cyclotrons 3 3. Synchrotons Synchrotons 3. Hadrontherapy Accelerators: 1. Prontontherapy 2. 2. Carbontherapy Carbontherapy 4. New concepts in Medical Accelerators: Cyclinacs and FFAGs 11
IFIC TRAINING COURSE R di ti Radiation Detectors (I) D t t (I) • Interaction of particles with matter Interaction of particles with matter – Should describe basic concepts like dE/dx, range... range... – Types of interactions with main emphasis in low energy electromagnetic interactions gy g • Particle detectors: general concepts – Should introduce the basic concepts like the – Should introduce the basic concepts like the “detection chain” (from interaction to electrical pulse), sensitivity, efficiency, dead time, pile- p ), y, y, , p up, position sensitive detectors, etc...
IFIC TRAINING COURSE R di ti Radiation Detectors (II) D t t (II) • Types of detectors: Types of detectors: – Gaseous detectors – Scintillation detectors – Scintillation detectors – Semiconductor detectors • New trends for particle detection New trends for particle detection – Describe novel technologies
IFIC TRAINING COURSE Image Science (I) g ( ) Course outline 1) Physics and image formation in medical imaging 1) Physics and image formation in medical imaging � Basics of transmission tomography: CT � Basics of emission tomography: SPECT, and PET � Image degradation processes � Image degradation processes 2) Image reconstruction techniques � Data formats � Analytical methods � Iterative approaches � Correction of image degradation processes 3) Image quality � Principal figures-of-merit � Observers and task-based analysis � Observers and task-based analysis
IFIC TRAINING COURSE Image Science (II) Image Science (II) � Requirements: R i � Some PCs should be available for lectures and students � The PCs should be equipped with some visualization tools � The PCs should be equipped with some visualization tools (such as AMIDE) � Exercises: � Each part will be followed by some exercises � For the exercises, the students should have access to personal PCs or carry their own laptops PCs or carry their own laptops � The exercises will be commented during the tutorial session
IFIC TRAINING COURSE EXPENDITURES(€) Cost Scientists/Students Number of days Total Accommodation 58 5 5 1450 Per diem 44 5 5 1100 Travel USA 2000 1 1 2000 Travel Europa 500 4 1 2000 Transport Transport 100 100 5 5 1 1 500 500 Local Transport 20 5 5 500 Coffee breaks 4 40 8 1280 Lunch 7 40 5 1400 Banquet 55 45 1 2475 12705
IFIC TRAINING COURSE Thank you very much for your attention J. B.
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