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- Dr. Wissam Zam
Faculty of Pharmacy
and their use in functional food Dr. Wissam Zam Faculty of - - PowerPoint PPT Presentation
and their use in functional food Dr. Wissam Zam Faculty of - - PowerPoint PPT Presentation
Extraction of polyphenols from Olive leaves and their use in functional food Dr. Wissam Zam Faculty of Pharmacy Functional foods 5/10 of deaths due to chronic diseases are caused by unhealthy diets Cardiovascular Type II Some Stroke
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5/10 of deaths due to chronic diseases are caused by unhealthy diets Cardiovascular disease
Saturated and trans fatty acids
Cholesterol
Sodium Refines sugars Some cancers
Stroke
Type II diabetes
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Functional foods
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Functional foods vs Dietary supplements
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اهفينصت قفو American Dietetic Association
Conventional foods Modified foods Medical foods Foods for special dietary use
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Common functional food
Common functional food
Probiotics & Prebiotics Antioxidants Vitamins and minerals Phytosterols and some phospholipids
- mega-3
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Olive leaves
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Olea europaea L.
Oleaceae
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Why?
Bioactive compounds Polyphenol (antioxidant) Oleuropein
20%
Diabetes Hypertension Bone health Anti-cancer effect In food as an antioxidant
Most abundant
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Why
The good absorption of its phenolic constituents Their good bioavailability Olive leaf extract (OLE) contains a higher quantity and variety of polyphenols than those found in olive oil
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Study design
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Problematic
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Results
Ethanol of 40% 60 °C 120 min
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Ionotropic gelation
53.80±2.59%
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In-vitro release study
20 40 60 80 100 120 30 60 120 180 240
In-vitro release in gastric medium Time Polyphenol release % Time Time Time In-vitro release in intestinal
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Publications
1. Zam Wissam, Ali Ali, Hasan Rama. Optimization of extraction conditions for the recovery of phenolic compounds and antioxidants from Syrian olive leaves. Journal of Pharmacognosy an d Phytochemistry. 2016;5(5):390-394. 2. Zam Wissam, Ali Ali. Olive leaves herbal tea effect in type 2 diabetic patients with
- prehypertension. European Journal of Pharmaceutical and Medical Research. 2017; 4(5), 55-59.
3. Zam Wissam, Ali Ali, Hasan Rama. Influence of different parameters on the preparation of oliv e leaves extract beads. Journal of Chemical and Pharmaceutical Science 2018;11(1):87-92.
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