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An Analysis of Agent-Oriented An Analysis of Agent Oriented Engineering of e-Health Systems g g y Em ilia Garcia Gareth Tyson Sim on Miles Michael Luck Gareth Tyson , Sim on Miles, Michael Luck, Adel Taweel, Tjeerd Van Staa, Brendan


  1. An Analysis of Agent-Oriented An Analysis of Agent Oriented Engineering of e-Health Systems g g y Em ilia Garcia Gareth Tyson Sim on Miles Michael Luck Gareth Tyson , Sim on Miles, Michael Luck, Adel Taweel, Tjeerd Van Staa, Brendan Delaney

  2. To what extent is AOSE an approach h h that is appropriate to the development pp p p of e-health system s ?

  3. Overview Overview • Analysis + case-study: Analysis + case study: ▫ e-Health system: ePCRN-IDEA  Challenges in e-Health system development g y p ▫ AOSE methodology: ROMAS methodology • Discussion • Conclusions

  4. e-Health system: ePCRN-IDEA e Health system: ePCRN IDEA  Clinical trials are experiments by which the efficacy of medical treatments are explored.  They involve recruiting patients with specific characteristics to undergo new treatments.  Difficulty to find patients with these requirements  Time restrictions.  ePCRN-IDEA is a new system under deployment in the UK  ePCRN IDEA is a new system under deployment in the UK healthcare system to enable real-tim e recruitm ent of patients for clinical trials.

  5. Ph Phase 1: Create and distribute clinical trial 1 C t d di t ib t li i l t i l • Research body creates a new clinical trial injecting it through y j g g a service called the Central Control Service (CCS) ▫ CSS is hosted at King's College London (KCL). ▫ The CCS stores trials within a large database in a pre-defined format that all researchers must adhere to. • Associated with each trial is a list of potentially eligible A i t d ith h t i l i li t f t ti ll li ibl patients ▫ These lists are generated by the General Practice Research Database g y (GPRD) • The trials and their eligibility lists are distributed to software h i l d h i li ibili li di ib d f agents (called LEPIS agents ) that operate on clinicians' PCs at each participating clinic.

  6. Ph Phase 2: Real-time eligible patients detection 2 R l ti ligibl ti t d t ti • During consultations LEPIS agents compare the patient information against the eligibility lists of all known trials. • If a patient is found to be eligible for a trial, ▫ The GP is notified ▫ If the patient is interested, the system loads a Random Clinical Trial (RCT) website allowing the patient's recruitment to be completed completed.

  7. e-Health system: ePCRN-IDEA e Health system: ePCRN IDEA • The following organizations are involved: g g ▫ The research bodies  Create clinical trials ▫ King´s College of London (KCL)  Store trials in a pre-defined format  Update clinic´s software information about trials and eligible  Update clinic s software information about trials and eligible patients ▫ General Practice Research Database (GPRD) ( )  Create list of potential eligible patients ▫ Participating clinics  Real-time patient´s information  Direct contact between GP and patients

  8. Challenges Challenges • Integration of Independent Systems. g p y ▫ Distributed Data ▫ Interoperability (techniques, processes, semantics) ▫ Trustworthiness • Regulation of Independent Systems • System Evolution. ▫ New legislation, software and medical techniques ▫ Adherence of new clinics

  9. ROMAS ROMAS methodology methodology • Regulated Open Multi-Agent Systems Regulated Open Multi Agent Systems ▫ heterogeneous and autonomous agents ▫ that coexist in a complex social and legal framework ▫ that address conflicting objectives of the many stakeholders th t dd fli ti bj ti f th t k h ld involved.

  10. ROMAS ROMAS overview overview  Social structure and coordination  Normative context: ◦ Norms ◦ Contracts ◦ Contracts  Social contracts  Contractual agreements

  11. ePCRN IDEA with ROMAS ePCRN-IDEA with ROMAS Challenges AOSE concepts Integration of Independent Systems Integration of Independent Systems Organizations roles agents Organizations, roles, agents - Distributed data Organizations, agents -Interoperability Services -Trustworthines T t thi C Contracts, norms t t Regulation of independent systems Norms and social contexts System evolution Services, contracts, norms

  12. ePCRN-IDEA with ROMAS ePCRN IDEA with ROMAS

  13. Discussion: Beneficial features of AOS Discussion: Beneficial features of AOS E E •Assumption of autonomy •Allowance for openness •Explicit norms •High level of abstraction concepts

  14. Discussion Discussion • The integration of specific e-Health term inology in the AOSE design process would facilitate the g p comprehension of the domain experts. • Although AOSE covers the analysis and design phases, there are not specific guidelines for capturing good practices for medicine and healthcare. ti f di i d h lth

  15. Conclusions Conclusions • The use of high level AOSE concepts , such as organizations, roles, services, norms and contracts, is beneficial to analyze y and design health systems. • The use AOSE techniques will produce flexible systems that can deal with the dynamics of the normative and technological d l i h h d i f h i d h l i l environment.

  16. Future work Future work • Integrate e-Health terminology with AOSE methodology • Guidelines for capturing good practices for medicine and h healthcare l h

  17. mgarcia@dsic.upv.es Emilia Garcia

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