Almac Overview www.almacgroup.com 2 Welcome to Almac 3 Who is - - PowerPoint PPT Presentation

www.almacgroup.com

Almac Overview

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Welcome to Almac…

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Who is Almac?

Almac is a world leading drug development & commercial services company; providing an expanding array of innovative solutions worldwide across the drug development lifecycle

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Our Vision Statement

“Almac will be the leader in the generation of superior solutions for the advancement of human health”

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Almac: An Integrated Group

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Milestones

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Background

Founded in 1968 Global Headquarters in Craigavon, Northern Ireland Turnover $0.5 billion+ (CMO market est. approx. $14bn) ~ 4,000+ Personnel Globally Unique ownership- charitable foundation: McClay Foundation All Profit Re-invested

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Our Global Presence

DEPOTS ON

60

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CONTINENTS

SHIPMENTS ANNUALLY TO OVER COUNTRIES

80 80

Facilities with 4,000+ personnel in:

• Europe : Northern Ireland,

Republic of Ireland, Scotland, England

• US: Pennsylvania, North

Carolina, California

• Asia: Japan, Singapore

To over 80 countries

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Diverse Customer Base

33% 10% 10% 29% 6% 5% 4% 2% Pharma - Large Pharma - Medium Pharma - Small Biotech CRO Academia Other Speciality Diagnostics 1%

Diverse client base across the Group assuring stability

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Overview of Almac’s market position

Clinical Services Clinical Technologies Pharma Services Sciences Diagnostics

Top 3 service provider for clinical supply services globally Industry leader – top 5 globally Smaller player, well known for solid oral dose capabilities Smaller player, broad range of service offerings supported by excellent science

Almac Group

Smaller player, more niche

• ffering

A unique range of services and solutions and a wide range of competitors (depending on which area of the business you look at) + Galen (branded pharmaceuticals) and Discovery (R&D)

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Discovery Pipeline

The Almac Group provides all of the services required to take a new drug or compound from concept right through to final patient delivery.

“World Class Pharmaceutical Solutions”

Discovery

Discovery R & D

Development

Process Development / Scale Up Formulation Development Clinical Trials

Delivery

Manufacturing & Packaging Sales & Marketing

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Services/Solutions

• Clinical Packaging
• Distribution
• Storage
• Blinding
• Commercial drug

procurement

• Supply chain

management

PHARMA SERVICES CLINICAL TECHNOLOGIES DIAGNOSTICS & BIOMARKERS CLINICAL SERVICES SCIENCES

• Interactive response

technology (IRT)

• Electronic patient

reported outcomes

• Bio statistical

services

• Pharmaceutical

development

• Commercial

manufacturing

• Commercial

Packaging

• Product launch,

distribution and

• ther commercial

services

• API services
• Chemical

development

• Analytical services
• Solid state services
• Biocatalysis
• Peptides
• Internal diagnostic

development

• Biomarker

discovery

• Companion

diagnostics development

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Discovery

Discovery R & D

Development

Process Development / Scale Up Formulation Development Clinical Trials

Delivery

Manufacturing & Packaging Sales & Marketing

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Discovery

• A project generator for highly novel oncology programmes

for the pharmaceutical companies.

• It operates in the discovery to preclinical space and

provides Phase I ready programmes.

• Exceptionally, it may chose to take a programme into

Phase I Clinical Trials

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Discovery

Discovery R & D

Development

Process Development / Scale Up Formulation Development Clinical Trials

Delivery

Manufacturing & Packaging Sales & Marketing

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Diagnostics

• Microarray based Cancer

Diagnostics Company

• Develops, markets and

supplies:

– Leading edge genomic expression services – Products that will radically improve the diagnosis and treatment of cancer

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Discovery

Discovery R & D

Development

Process Development / Scale Up Formulation Development Clinical Trials

Delivery

Manufacturing & Packaging Sales & Marketing

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Sciences

• API Supply

– Synthesis design – Peptide API

• Drug Product

– Clinical manufacture – Scale up

• Analytical Services

– Stability – Release and comparator testing – Method development

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Discovery

Discovery R & D

Development

Process Development / Scale Up Formulation Development Clinical Trials

Delivery

Manufacturing & Packaging Sales & Marketing

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Clinical Services

• Clinical Supplies management

company

• Covers complete supply chain

for Clinical Trials:

– blinding – packaging – global distribution – consulting/project management

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Discovery

Discovery R & D

Development

Process Development / Scale Up Formulation Development Clinical Trials

Delivery

Manufacturing & Packaging Sales & Marketing

Clinical Technologies

Supported nearly

2 million

patients Worked with

18/20

top biopharma companies Renowned biostats staff Conducted trials in

60

languages Managed

2000+

clinical studies to date Global trials conducted across 85 countries

Interactive Response Technology - IXRS

Patient Randomization & Blind Protection Product Inventory Management Patient Tracking & Status Study Management Data Availability

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Discovery

Discovery R & D

Development

Process Development / Scale Up Formulation Development Clinical Trials

Delivery

Manufacturing & Packaging Sales & Marketing

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Pharma Services

Formulation Development

• - from API to tablet

Commercial Manufacture & Packaging Distribution & Logistics

• - global distribution
• - inventory management (TROPOS)
• - 3PL & POP
• - late stage customisation

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Discovery

Discovery R & D

Development

Process Development / Scale Up Formulation Development Clinical Trials

Delivery

Manufacturing & Packaging Sales & Marketing

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Galen

• Galen promotes branded and generic prescription

medicines in the UK & Ireland e.g.

– Calceos (for osteoporosis) – Laxido Orange (for chronic constipation) – Flotros (for overactive bladder) – Penthrox (Analgesic) Launched Jan 2016

• Trustsaver Portfolio

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Commercialisation – Galen

• Galen Ltd
• Recognised Speciality Pharmaceutical Company
• Products Sold into 23 Countries
• Successful Entrance into US Market in 2012
• Therapy Areas include:
• Oncology
• Gastroenterology
• Female Health
• Pain Management

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The Future

• We are a global player and we will continue to

increase our presence throughout the world.

• We will continue to develop new technologies,

new medical interventions and new markets.

• We will achieve our vision.