AC HEMP OIL LIPOSOME PF 61005PF AC Hemp Oil Liposome PF - - PowerPoint PPT Presentation

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AC HEMP OIL LIPOSOME PF 61005PF AC Hemp Oil Liposome PF - - PowerPoint PPT Presentation

Oct 17, 2023 43 likes •217 views

AC HEMP OIL LIPOSOME PF 61005PF AC Hemp Oil Liposome PF Anti-Inflammation + Liposome Technology + CBD Product Code: 61005PF INCI Name: Water & Phospholipids & Cannabis Sativa Flower/Leaf/Stem Extract INCI Status: Conforms Suggested Use

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AC HEMP OIL LIPOSOME PF

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61005PF AC Hemp Oil Liposome PF

Anti-Inflammation + Liposome Technology + CBD

Product Code: 61005PF INCI Name: Water & Phospholipids & Cannabis Sativa Flower/Leaf/Stem Extract INCI Status: Conforms Suggested Use Levels: 1.0 – 10.0% Suggested Applications: Anti-Inflammation, Liposome Technology Solubility: Water Dispersible

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  • ‘Inflammaging’, aging accelerated by inflammation, is the turning

point driving the skin care industry.

  • Cannabinoids and cannabidiol (CBD) are the new darlings of the

anti-inflammatory market and scientific discoveries in that area are driving the industry forward.

  • AC Hemp Oil Liposome PF capitalizes on the anti-inflammatory

benefits associated with hemp oil while using modern encapsulation technology to enhance activity and stability.

61005PF AC Hemp Oil Liposome PF

Product Overview

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  • Inflammation is a driving force behind the skin aging process,

leading to a breakdown of the extracellular matrix and consequential skin wrinkling.

  • Inflammation is the body’s response to cellular aggression or injury
  • Represents a defense mechanism designed to heal cells from

injury and protect the body

  • Facilitates early tissue healing and repair
  • Allows the body to restore itself to a normal form and function
  • All skin is subject to inflammation, even at low intensities.

61005PF AC Hemp Oil Liposome PF

Inflammation as a Precursor to Skin Aging

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  • It is this underlying inflammation that ultimately

exhausts the body’s defense system, dismantling key youth-sustaining skin structures, and resulting in collagen and elastin degradation, as well as a breakdown of the skin’s barrier function.

  • Inflammaging can be alleviated and prevented by the

use of topical products formulated with anti- inflammatory actives.

61005PF AC Hemp Oil Liposome PF

Inflammation as a Precursor to Skin Aging

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  • Humans have made use of the hemp plant — and its nutritional benefits —

since the beginning of written history.

  • It is believed that weaving of hemp fibers began thousands of years ago and

have been used industrially to manufacture rope, canvas, paper, and clothing.

  • After the discovery of textiles and synthetics, hemp fiber weaving or

manufacturing began to disappear.

  • Today hemp products are making a comeback particularly with hemp oil.

61005PF AC Hemp Oil Liposome PF

Hemp Oil on the Rise

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61005PF AC Hemp Oil Liposome PF

Capitalizing on Hemp Oil & CBD Oil in Cosmetics Milk Makeup

KUSH High Volume Mascara, Lip Glaze, and Lip Balm

“Hemp-derived cannabis oil fuses the heart-shaped fibers to lashes, while providing an additional conditioning benefit. Conditioning, hemp-derived cannabis oil soothes and hydrates lips.”

ORIGINS

Hello, Calm Relaxing & Hydrating Face Mask

“This lush, super-nourishing mask is formulated with cannabis sativa seed oil from hemp. An ultra-hydrating mask infused with natural cannabis sativa seed oil to instantly calm skin, visibly reduce irritation, and de-stress the senses.”

The Body Shop

Hemp Hand Protector

“Best-selling Hemp Hand Protector is dermatologically tested for very dry skin contains Community Fair Trade hemp seed

  • il. Hemp seed oil contains unusually high concentrations of

essential fatty acids that repair skin's moisture barrier, so skin is smooth and supple.”

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  • Hemp oil is produced by gentle cold press extraction from the

specialized varietals of the hemp plant of the Cannabis genus.

  • The plants used for the extractions are specifically cultivated to have the

insignificant amounts of the psychoactive substances associated with the genus, most notably the tetrahydrocannabinol (THC).

  • AC Hemp Oil Liposome PF is manufactured using hemp oil rich in CBD.
  • While the hemp oil we use contains high CBD, it is not the same thing as

CBD oil, which is a purified hemp oil product. When strains are high in CBD, they are subsequently very low in THC, typically containing < 0.3%

  • THC. The produced hemp oil used in the manufacturing of AC Hemp Oil

Liposome does not have psychoactive properties.

61005PF AC Hemp Oil Liposome PF

Hemp Oil

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  • AC Hemp Oil Liposome PF contains hemp oil extracted from the

whole hemp plant.

  • Hemp contains an entourage of over 400 compounds including

CBD, secondary phyto-cannabinoids, terpenoids, terpenes, and

  • flavonoids. These compounds work synergistically to heighten

the positive, therapeutic effects of CBD.

  • The “Entourage Effect” is a term coined by scientists in 1998 to

describe their study findings that taking all of the natural chemicals found in cannabis are more beneficial than just taking a single molecule compound.

  • A CBD product made with isolated CBD will not contain these
  • ther beneficial factors.

61005PF AC Hemp Oil Liposome PF

The Entourage Effect

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  • AC Hemp Oil Liposome PF encapsulates hemp oil into liposomes for enhanced stability and delivery.
  • Liposomes act as vehicles to transport nutrients to the cells through layers of skin and enhance

delivery of active ingredients.

61005PF AC Hemp Oil Liposome PF

Liposomal Delivery System

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  • Liposomes are readily compatible with epidermal surface lipids, the skin’s primary moisture barrier.
  • When a liposome fuses with the epidermal lipids, the epidermal lipid structure becomes overloaded

with water and out of equilibrium.

  • To restore equilibrium, the water and phospholipid, as well as the active loaded, are rapidly churned

through the top cell layers of the stratum corneum.

  • Enhanced delivery of the active occurs as it is rapidly carried down through the stratum corneum.
  • Liposomes’ proven delivery system yields a multitude of benefits; enhancing the penetration of

actives yielding increased efficacy, offering time release mechanisms, and protecting and delivering

  • therwise unstable ingredients.

61005PF AC Hemp Oil Liposome PF

Liposomal Delivery System Mechanism of Action

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Hydrophilic Heads Lipophilic Tails Water Soluble Actives Oil Soluble Actives

61005PF AC Hemp Oil Liposome PF

Liposomal Delivery System

Liposome approaches skin barrier layer Liposome breaks and fuses with skin barrier layer Liposome dissolves and releases actives

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  • AC Hemp Oil Liposome PF can be used to

reduce inflammation and capitalize on the benefits of hemp oil in a variety of hair and skin care formulations.

  • The inhibition of Interleukin-6 activity by AC

Hemp Oil Liposome PF may help to alleviate the chronic inflammatory process, which is linked to the process of skin aging and the formation of fine lines and wrinkles.

61005PF AC Hemp Oil Liposome PF

Cosmetic Benefits

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61005PF AC Hemp Oil Liposome PF

in-vitro Anti-Inflammation Assay

Protocol

  • Human dermal fibroblasts were allowed to grow

to confluency in complete DMEM

  • AC Hemp Oil Liposome PF was added to

complete DMEM containing 1μg/mL LPS and incubated with fibroblasts for 24 hours.

  • Complete media containing 1μg/mL LPS was

used as the positive controls and complete DMEM was used as the negative control.

  • AC Hemp Oil Liposome PF exhibited anti-

inflammatory effects on LPS-treated fibroblasts.

  • As expected, the changes in IL-6 production

using AC Hemp Oil Liposome PF appear to be does dependent.

1.849 2.0547 50.479 120.6164384 42.3 260.616 2.26

50 100 150 200 250 300

2.0% AC Hemp Oil Liposome PF 1.0% AC Hemp Oil Liposome PF 0.5% AC Hemp Oil Liposome PF 1.0% CBD Oil 1ug/ml LPS + DEX Iug/ml LPS Complete Media

IL-6 Concentration (pg/mL)

IL-6 Concentration

Figure 1. Decrease in IL-6 concentration in human dermal fibroblasts..

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Figure 2. Percent change in IL-6 Concentration for test materials.

Protocol

  • AC Hemp Oil Liposome PF exhibited anti-

inflammatory effects on LPS-treated fibroblasts

  • AC Hemp Oil Liposome PF decreased IL-6

concentration by 83.77% at a 0.5% use level and by 99.22% at a 1.0% use level

  • Non-encapsulated CBD oil was tested for added

perspective

  • Results of this IL-6 ELISA assay demonstrate that

1.0% AC Hemp Oil Liposome PF reduces IL-6 concentration 45.51% more than 1.0% CBD oil

61005PF AC Hemp Oil Liposome PF

in-vitro Anti-Inflammation Assay

  • 99.29052706
  • 99.21159867
  • 83.76922369
  • 53.71871322
  • 83.76922369
  • 120
  • 100
  • 80
  • 60
  • 40
  • 20

2.0% AC Hemp Oil Liposome PF 1.0% AC Hemp Oil Liposome PF 0.5% AC Hemp Oil Liposome PF 1.0% CBD Oil 1ug/ml LPS + DEX

Percent (%) Change

Percent Change in IL-6 Concentration

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61005PF AC Hemp Oil Liposome PF

Anti-Inflammation + Liposome Technology + CBD

Product Code: 61005PF INCI Name: Water & Phospholipids & Cannabis Sativa Flower/Leaf/Stem Extract INCI Status: Conforms Suggested Use Levels: 1.0 – 10.0% Suggested Applications: Anti-Inflammation, Liposome Technology Solubility: Water Dispersible

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Active Concepts, LLC Lincolnton, NC. USA

  • www. activeconceptsllc.com

Office: +1 704 276 7100 info@activeconceptsllc.com

AC HEMP OIL LIPOSOME PF