What were neurons invented for? 2 1 1/25/17 To move things is all - PDF document

Jun 27, 2023 •39 likes •149 views

1/25/17 What were neurons invented for? 2 1 1/25/17 To move things is all that mankind can do...for such the sole executant is muscle, whether in whispering a syllable or in felling a forest. Charles Sherrington 1924 3

1/25/17 What were neurons invented for? 2 1
1/25/17 “To move things is all that mankind can do...for such the sole executant is muscle, whether in whispering a syllable or in felling a forest.” Charles Sherrington 1924 3 “Sensorimotor Brain system” Sensors Muscles 4 2
1/25/17 Lab 1: Neurons and the Brain (and Matlab) Neuroscience primer: Brain & neuron Membrane potential Action potential Synaptic transmission • Lab part 1: Neurons in Matlab • Lab part 2: Brain in 3D Online 3
1/25/17 ACTING! SENSING The Brain motor cortex (voluntary movement) prefrontal cortex visual (planning; cortex working memory) cerebellum brainstem (movement coordination (involuntary, movement learning) reflexive behaviors) • Approximately 10 11 neurons in a human brain • Approximately 10 15 synapses connecting them 4
1/25/17 Neurons and synapses (~10 -3 mm) 10 μm Lab 1: Neurons and the Brain (and Matlab) Neuroscience primer: Brain & neuron Membrane potential Action potential Synaptic transmission • Lab part 1: Neurons in Matlab • Lab part 2: Brain in 3D Online 5
1/25/17 Neurons send fast long-distance signals Membrane potential: charge imbalance 6
1/25/17 The electrical properties of neurons are what enables them to regulate every aspect of behavior. - + -65 mV Membrane potential aka membrane voltage is the difference between the electric potential outside vs inside the cell: Vm = Vin – Vout 7
1/25/17 Adding plus charge (positive current ) inside the cell makes the inside less negative compared to the outside 16 http://howmed.net/physiology/action-potential/ 8
1/25/17 Spikes! Firing rate = (number of spikes)/(time) Excitation: higher firing rate Inhibition: lower firing rate and membrane is hyperpolarized Propagation 18 http://www.rci.rutgers.edu/~uzwiak/AnatPhys/APFallLect18.html 9
1/25/17 Lab 1: Neurons and the Brain (and Matlab) Neuroscience primer: Brain & neuron Membrane potential Action potential Synaptic transmission • Lab part 1: Neurons in Matlab • Lab part 2: Brain in 3D Online Neuron-to-neuron Synapse 10
1/25/17 21 11

Download Presentation

Download Policy: The content available on the website is offered to you 'AS IS' for your personal information and use only. It cannot be commercialized, licensed, or distributed on other websites without prior consent from the author. To download a presentation, simply click this link. If you encounter any difficulties during the download process, it's possible that the publisher has removed the file from their server.

Recommend

Vi t Virtual Neurons l N 3D reconstructions of neurons 3D-reconstructions of neurons Manos

Vi t Virtual Neurons l N 3D reconstructions of neurons 3D-reconstructions of neurons Manos Papadakis p University of Houston Collaborators I. Kakadiaris, I. Kakadiaris, D. Labate Neuroscience/data acquisition collaborators: q P. Saggau

412 views • 39 slides

Mirror neurons Mirror neurons (MNs) = sub-populations of motor neurons that discharge both

Mirror neurons Mirror neurons (MNs) = sub-populations of motor neurons that discharge both when the individual executes and observes an action Motor neuron fires during action (self-)execution Concepts: movement, motor act, motor

169 views • 4 slides

Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons of neurons

Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons of neurons Zhang J, Cicero SA, Wang L, Romito Digiacomo RR, Yang Y, Herrup K. P Proc Natl Acad Sci U S A. 2008 Jun 4;105(25):8772 7. N tl A d S i U S A

302 views • 28 slides

The cable equation A.K.A. the monodomain model Neurons Electric flow in neurons The neuron

The cable equation A.K.A. the monodomain model Neurons Electric flow in neurons The neuron consists of three parts: Dendrite-tree, the input stage of the neuron, converges on the soma. Soma, the cell body, contain the normal

297 views • 17 slides

MATHEMATICAL THINKING A guest lecture by Mr. Chase Is mathematics invented or discovered?

MATHEMATICAL THINKING A guest lecture by Mr. Chase Is mathematics invented or discovered? Aristotle Plato Is mathematics invented or discovered? Options: Poll! 1. Invented 2. Discovered 3. Unresolvable 4. I dont know Newton and

341 views • 18 slides

Neural Networks Overview CS89.11/189.2 - Spring 2020 Our Neurons Our Neurons Dendrites Our

Neural Networks Overview CS89.11/189.2 - Spring 2020 Our Neurons Our Neurons Dendrites Our Neurons Dendrites Axon Our Neurons Dendrites Axon terminals Axon Our Neurons Dendrites I 0 I 1 Axon terminals I 2 I 3 Axon I 4 I 5 I m Our

356 views • 20 slides

NEUROBIOLOGY central nervous system (CNS) = brain / spinal cord ~100 billion neurons

NEUROBIOLOGY central nervous system (CNS) = brain / spinal cord ~100 billion neurons all thoughts / behaviors / memories result from biochemical interactions between neurons Drugs that affect these processes are psychoactive

413 views • 27 slides

Mathematical Neuroscience: from neurons to networks Part I Cortex Steve Coombes School of

Mathematical Neuroscience: from neurons to networks Part I Cortex Steve Coombes School of Mathematical Sciences Neurons: pyramidal cells Hodgkin and Huxley (1950s) express (and subsequently fit) the dynamics of gating variables

835 views • 48 slides

NEURAL NETWORKS NEURAL NETWORKS THE IDEA BEHIND ARTIFICIAL NEURONS Initially a simplified

NEURAL NETWORKS NEURAL NETWORKS THE IDEA BEHIND ARTIFICIAL NEURONS Initially a simplified model of real neurons A real neuron has inputs from other neurons through synapses on its dendrites The inputs of a real neural are weighted!

499 views • 12 slides

Lecture 1: Neurons Lecture 2: Coding with spikes Lecture 3: Tuning curves and receptive fields

Lecture 1: Neurons Lecture 2: Coding with spikes Lecture 3: Tuning curves and receptive fields Learning objectives: To gain a basic understanding of how neurons represent the environment 1. Name some of the parameters that one can extract from

692 views • 52 slides

Communication Between Neurons Synapse: A specialized site of contact, and transmission of

Communication Between Neurons Synapse: A specialized site of contact, and transmission of information between a neuron and an effector cell Anterior Motor Neuron Figure 45-5 Communication Between Neurons Chemical synapse

1.13k views • 66 slides

Evolving adaptive coincidence-detecting neurons W. Garrett Mitchener College of Charleston

Evolving adaptive coincidence-detecting neurons W. Garrett Mitchener College of Charleston January 10, 2015 W. Garrett Mitchener (C of C) Evolving neurons January 10, 2015 1 / 23 Neurons & action potentials Neurons and action potentials

573 views • 46 slides

1 Neurons in the PNS and CNS have many different forms presynaptic neurons Cell biological

Symptoms of spinal cord injury: involuntary muscle spasms loss of voluntary movement sensation, balance control of breathing autonomic functions (blood pressure) bladder, sexual, bowel control All due to destruction of long

356 views • 22 slides

The Autonomic Nervous System and Visceral Sensory Neurons The Autonomic Nervous System and Visceral

The Autonomic Nervous System and Visceral Sensory Neurons The Autonomic Nervous System and Visceral Sensory Neurons The ANS a system of motor neurons The general visceral motor division of the PNS Innervates smooth muscle, cardiac

439 views • 29 slides

Not Invented Here Syndrome and Dark Debt: The PagerDuty Story AISH RAJ DAHAL Section I Why

Not Invented Here Syndrome and Dark Debt: The PagerDuty Story AISH RAJ DAHAL Section I Why are we here ? Not Invented Here Syndrome the tendency towards reinventing the wheel based on the belief that in-house developments are

740 views • 50 slides

Joe the Box Joe the Box is a little bit of history first invented by Adele Goldburg for

Joe the Box Joe the Box is a little bit of history first invented by Adele Goldburg for Smalltalk 72 Joe the Box Alan Kay used it in a 1977 Scientific American article Two roles: a microworld for exploring object interaction

425 views • 3 slides

1 Cerebrum Pre- frontal Cortex Cerebellum Brain Stem Moral/Abstract Reasoning Empathy

Oh boy , I sure hope this Shh. He might use I can see Albuquerque! guy presents things we Edu - jargon to can really use. sound impressive. Do I dare disturb the universe? Dare! Dare! These political times in education are rough

754 views • 34 slides

The Central Nervous System Components Brain Spinal Cord 1 Protection of the Brain

The Central Nervous System Components Brain Spinal Cord 1 Protection of the Brain The brain is protected from injury by The skull enough said! You already know this. What else protects your Brain? 2 Protection of

916 views • 55 slides

ES514 Emerging Pedagogies The Brain Embodied Brains, Social Minds

ES514 Emerging Pedagogies The Brain Embodied Brains, Social Minds https://www.youtube.com/watch?v=RViuTHBIOq8 What we are learning about neurobiology of social emotions shape the way we learn and how we use what we learn. The

469 views • 30 slides

Solid Organ Replacement, Transplant and Donation Webinar 12 th September 2019 Presenters Martin

Solid Organ Replacement, Transplant and Donation Webinar 12 th September 2019 Presenters Martin Ashton-Key Scientific Director and Consultant in Public Health Medicine, NETSCC Claire Gregory Senior Research Manager, NETSCC Questions Please

392 views • 20 slides

Yoga for Respiratory Function Yoga Alliance Webinar April 30, 2020 Sat Bir S. Khalsa, Ph.D.

Brigham & Womens Hospital Harvard Medical School Yoga for Respiratory Function Yoga Alliance Webinar April 30, 2020 Sat Bir S. Khalsa, Ph.D. Assistant Professor of Medicine, Harvard Medical School Director of Yoga Research, Yoga

731 views • 38 slides

Morit Heitzler Morit Heitzler The Body of the Traumatised Client Morit Heitzler Neuroscience

The Clients Body and the Therapists Body in Integrated Trauma work Morit Heitzler Morit Heitzler The Body of the Traumatised Client Morit Heitzler Neuroscience has clearly established that trauma and PTSD significantly alters brain

787 views • 37 slides

Vision: From Eye to Brain (Chap 3) Lecture 7 Jonathan Pillow Sensation & Perception (PSY

Vision: From Eye to Brain (Chap 3) Lecture 7 Jonathan Pillow Sensation & Perception (PSY 345 / NEU 325) Princeton University, Fall 2017 early visual pathway eye eye optic nerve optic chiasm optic tract lateral geniculate

289 views • 24 slides

Y P O C Combining TMS and EEG T O N O D E S A E L Mouhsin Shafi, MD/PhD P Harvard

Y P O C Combining TMS and EEG T O N O D E S A E L Mouhsin Shafi, MD/PhD P Harvard Medical School mshafi@bidmc.harvard.edu Y Talk Overview P O Intro to TMS and EEG C Technical issues and challenges T O

995 views • 78 slides