Trends in Hospitalizations among HIV- infected Children in New York - - PowerPoint PPT Presentation
Trends in Hospitalizations among HIV- infected Children in New York City Kai-Lih Liu, Ph.D., MPH 1 ; Vicki Peters, MD 1 ; Balwant Gill, Ph.D. 1 ; Chere Mapson, RN, MS 1 ; Annette Brooks 1 ; Pauline Thomas, MD 1 ; and Kenneth Dominguez, MD, MPH 2 .
Kai-Lih Liu, Ph.D., MPH1; Vicki Peters, MD1; Balwant Gill, Ph.D.1; Chere Mapson, RN, MS1; Annette Brooks1; Pauline Thomas, MD1; and Kenneth Dominguez, MD, MPH2.
1New York City Department of Health and Mental Hygiene, New York; 2Centers for Disease Control and Prevention, Atlanta, GA.
Poster Presentation at the 40th Annual Meeting of Infectious Diseases Society of America (IDSA) Chicago, October 24-27, 2002
To describe trends in hospitalizations among HIV-
To compare hospitalization rates, length of stay,
The Pediatric Spectrum of HIV Disease Project (PSD) is
Data is collected retrospectively from pediatric medical
This analysis includes children enrolled at the 10 New
Children Observed is defined as children who have
Hospitalization data included:
Number of Admissions Year of Admission Length of Stay Age at Admission Hospital Discharge Diagnoses
Reasons for hospitalization, based on hospital discharge
HIV-related (CDC clinical categories A-C) Probably HIV-related (e.g., pneumonias without specific
Non HIV-related (e.g., asthma, surgery for appendicitis,
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% 1995 1996 1997 1998 1999 2000
>=13 Years 6-12 Years 1-5 Years <1 Year
N=887 N=845 N=817 N=806 N=785 N=725
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% 1995 1996 1997 1998 1999 2000
Severe Moderate None
* 13% of children with missing information on CD4 Counts CD4+ age-specific immunosuppression
Note: Chi-square test for trend shows a significant decreasing trend in number of children hospitalized from 1995 to 2000 (p<0.00001). * Hospitalization Rate (per 100 children observed) within each year = (Total Number of Admissions / Number of Children Observed) x 100
* Within each age group, percentage of children hospitalized at least once =(Number of Hospitalized Children / Number of Children Observed) x 100
5 10 15 20 25 30 35 40 45 50 1995 1996 1997 1998 1999 2000
Year of Admission
<1 Year 1-5 Years 6-12 Years >=13 Years
%
* Hospitalization Rate within each year = (Number of Admissions / Number of Children Observed) x 100
10 20 30 40 50
Non HIV-related 4 6 4 3 4 4 Probably HIV-related 13 10 7 7 5 4 HIV-related 28 27 22 15 10 8 1995 1996 1997 1998 1999 2000
Note: Chi-square test for linear trend shows a significant decreasing trend in hospitalization rates by reasons for hospitalization (p=0.004). Rate per 100 children
N Median Range Mean* 95% C.I.
* ANOVA test of differences in mean length of stay by reason for hospitalization: p<0.0001
0% 20% 40% 60% 80% 100%
HIV-related Probably HIV- related Non HIV- related
<1 Year 1-5 Years 6-12 Years >=13 Years
Note: No significant differences in the distribution of age at admission by reasons for hospitalization (p=0.48).
From 1995 to 2000, the number of admissions and
The median and mean length of stay did not vary
Hospitalization rates decreased for both HIV-related
The age-specific percentage of hospitalized children
The decreasing hospitalization trend among HIV-
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Participating Institutions and Pediatricians at NYC sites Project Staff at the New York City Department of Health and Mental Hygiene