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TEConomy 2018 Evidence and Opportunity: Impact of Life Sciences in North Carolina Bill Bullock March 28, 2019 ncbiotech.org ncbiotech.org TEConomy NC Life Science Report 2018 Evaluation/Comparison of North Carolinas Life Science

  1. TEConomy 2018 Evidence and Opportunity: Impact of Life Sciences in North Carolina Bill Bullock March 28, 2019 ncbiotech.org ncbiotech.org

  2. TEConomy NC Life Science Report 2018 • Evaluation/Comparison of North Carolina’s Life Science Industry (BLS data) • Economic Impact of North Carolina’s Life Science Industry (NCBiotech data) • Role/Impact of the North Carolina Biotechnology Center • North Carolina’s Biomanufacturing Sector • Evidence and Opportunity 2 ncbiotech.org

  3. Innovating Tomorrow’s Economic Landscape TEConomy TEConomy Partners is a global leader in research, analysis and strategy for innovation- driven economic development. Today we’re helping nations, states, regions, universities, institutions and industries blueprint their future and translate knowledge into prosperity. 3 ncbiotech.org

  4. Evaluation/Comparison of North Carolina’s Life Science Industry 4 ncbiotech.org

  5. Growth of NC Life Science Industry 5 ncbiotech.org

  6. Classifying & Measuring • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 6 ncbiotech.org

  7. Life Sciences in North Carolina vs US • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 7 ncbiotech.org

  8. North Life Science Industry • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 8 ncbiotech.org

  9. US Life Science Clusters • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 9 ncbiotech.org

  10. Life Science Wages • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 10 ncbiotech.org

  11. Economic Impact of North Carolina’s Life Science Industry 11 ncbiotech.org

  12. North Carolina Life Science Industry (NCBiotech) • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 12 ncbiotech.org

  13. Economic Contribution of NC’s Life Science Industry 13 ncbiotech.org

  14. A Decade of Growth • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 14 ncbiotech.org

  15. Economic Contribution by Segment Output ($M) Labor ($M) Employment Taxes ($M) Total Life Science 83,311 16,680 240,281 2,181 Ag Feedstock 9% 6% 6% 7% Drugs & Pharma 68% 58% 55% 65% Med Device 4% 5% 5% 4% Res, Testing, Lab 16% 29% 31% 20% Distribution, other 3% 2% 3% 4% 15 ncbiotech.org

  16. Life Science is Statewide in North Carolina 16 ncbiotech.org

  17. NCBiotech Commuting Study 2018 Representing Life Science Employment in North Carolina, by employees' counties of residence There are more than 63,000 employees at 700+ life science companies across North Carolina.  This study show the home counties of employees at 58 sites: West PiedmontTriad Triangle East  Adhezion Biomedical(Hudson)  AccuMED Technologies(Mocksville)  Biogen(RTP)  Avoca (MerryHill)  Avadim Technologies (Asheville)  Carolina Liquid Chemistries (Greensboro)  Grifols(Clayton)  CMP Pharma (Farmville)  Baxter(Marion)  Cook Medical (Winston-Salem)  GSK(RTP)  Fresenius Kabi(Wilson)  Exela Pharma Sciences(Lenoir)  EN-CAS Analytical Labs (Winston-Salem)  GSK(Zebulon)  Mayne Pharma (Greenville)  Gaia Herbs(Brevard)  Herbalife(Winston-Salem)  Mayne Pharma (Raleigh)  Microbac Laboratories(Wilson)  Genova Diagnostics(Asheville)  High Point Clinical Trials Center (High Point)  Medicago(Durham)  Pfizer (RockyMount)  PharmAgra Labs (Brevard)  KeraNetics(Winston-Salem)  Novo Nordisk(Clayton)  Purdue Pharmaceuticals(Wilson)  Stallergenes Greer(Lenoir)  LabCorp(Burlington)  Novozymes(Franklinton)  RTI Surgical(Greenville)  Piedmont Animal Health (Greensboro)  Novozymes BioAg(RTP)  Sandoz(Wilson)  Procter & Gamble (BrownsSummit)  Pfizer(Sanford)  Thermo Fisher Scientific(Greenville) GreaterCharlotte  SightLife Surgical (Winston-Salem)  Purdue Pharma Manufacturing(Durham)  Carolinas HealthCare System Division of Therapeutic  Syngenta Crop Protection (Greensboro)  Syngenta Crop Protection(RTP) Southeast Research & Development(Charlotte)  Thermo Fisher Scientific (High Point)  CEM Corp.(Matthews)  Alcami(Wilmington)  vTv Therapeutics (HighPoint)  Chemring Detection Systems (Charlotte)  Amyris(Leland)  David H. Murdock Research Institute (Kannapolis)  Cygnus Technologies(Southport)  Glenmark Pharmaceuticals (Monroe)  Huvepharma(Maxton)  LANXESS Solutions(Gastonia)  Novella Clinical (Wilmington)  Meridian Laboratory Corp. (Charlotte)  Quality Chemical Laboratories (Wilmin  Microban International(Huntersville) ncbiotech.org Complied by the North Carolina Biotechnology Center, April 2018

  18. Role/Impact of the North Carolina Biotechnology Center 18 ncbiotech.org

  19. North Carolina Biotechnology Center • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 19 ncbiotech.org

  20. North Carolina Biotechnology Center • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 20 ncbiotech.org

  21. Economic Contribution of the North Carolina Biotechnology Center • Active loan portfolio (107 companies):  $3.8B annual economic output  $732M annual labor income  10,390 employment (2,544 direct)  $98M annual state/local taxes • Life science recruitment/expansion (25 companies FY 2017-18):  $2.1B annual economic output  $580M annual labor income  8,732 employment (3,080 anticipated direct)  $59M annual state/local taxes 21 ncbiotech.org

  22. New Programs • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 22 ncbiotech.org

  23. North Carolina’s Biomanufacturing Industry 23 ncbiotech.org

  24. What is Biomanufacturing? 24 ncbiotech.org

  25. Biomanufacturing Growth in North Carolina • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 25 ncbiotech.org

  26. Economic Contribution of Biomanufacturing in NC • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 26 ncbiotech.org

  27. Biomanufacturing Employment Growth in NC • Agricultural Feedstock & Industrial Biosciences • Bioscience-Related Distribution • Drugs & Pharmaceuticals • Medical Devices & Equipment • Research, Testing & Medical Labs 27 ncbiotech.org

  28. 2018 Evidence and Opportunity Evidence “North Carolina has established one of the nation’s leading life science clusters, characterized by steady, long-term growth and establishment of a diverse blend of industry, technology and market strengths and niches… The industry’s standing and top -tier position today has been hard-earned, however, in large part due to the early and consistent dedication of the North Carolina Biotechnology Center, with funding from the State of North Carolina, through an emphasis on industry and ecosystem development programs and initiatives.” Opportunity Talent, Infrastructure, Investment 28 ncbiotech.org

  29. 29 ncbiotech.org

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