Strategic partner for the Qubec health system MOTHERS MILK - - PDF document

CORPORATE PRESENTATION Strategic partner for the Québec health system

MOTHER’S MILK STEM CELLS STABLE PRODUCTS BLOOD PRODUCTS HUMAN TISSUES

To efficiently meet the needs

• f the Québec population

for quality blood and other biological products of human origin.

MISSION

To become a strategic partner for the Québec health system.

VISION

HÉMA-QUÉBEC DONORS HOSPITALS BIOVIGILANCE COMMITTEE HEALTH CANADA MINISTER OF HEALTH AND SOCIAL SERVICES RECIPIENTS

BLOOD AND BIOLOGICAL PRODUCTS OF HUMAN ORIGIN SYSTEM IN QUÉBEC

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FROM SUPPLIER OF BLOOD PRODUCTS TO EXPERT IN BIOLOGICAL PRODUCTS OF HUMAN ORIGIN

1980 1992 1989 1996 1997 1998

First cases of HIV transmitted through blood Contaminated blood scandal Adoption of the Act Respecting Héma-Québec – Héma-Québec starts its operations Creation of the unrelated bone marrow donor registry in Canada Release of the Gélineau Committee report The Red Cross announces its withdrawal from the Canadian blood program as of September 1998 – Krever Commission report tabled

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T IN BIOLOGICAL PRODUCTS OF HUMAN ORIGIN

2001 2003 2005 2011 2013 2014

Revision of the Act Respecting Héma-Québec: extended mandate to biological products of human origin – Opening of the Mobile Blood Drive Regional Centre – Opening of the first GLOBULE Blood Donor Centre Opening of the first PLASMAVIE Plasma Donor Lounge – Operational start-up of the first GLOBULE Mobile Blood Donation Unit Creation of the Québec Public Cord Blood Bank Creation

• f the no-fault

compensation scheme Acquisition of the assets of the Centre de conservation de tissus humains du Québec – Creation of the Québec Public Mothers’ Milk Bank Héma-Québec assumes full management of the Stem Cell Donor Registry in Québec

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EMPLOYEES

1,347

OF VOLUNTEERS

THOUSANDS

2017–2018 ANNUAL REVENUE

$450M

A great team dedicated to the gift of life

BLOOD, STEM CELL, MOTHER’S MILK AND HUMAN TISSUE DONORS

CLOSE TO

225,000

HÉMA-QUÉBEC IS...

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PERMANENT PRESENCE THROUGHOUT QUÉBEC

Facility GLOBULE Mobile Blood Drive Regional Centre PLASMAVIE Drop-off point for mother’s milk PLASMAVIE with a blood donation area Trois-Rivières Montréal Saint-Laurent Brossard Saguenay Gatineau Sherbrooke

Québec

Laval

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BLOOD PRODUCTS

Justine makes her first blood donation.

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BLOOD PRODUCTS

COLLECTIVE BLOOD SUPPLY

BLOOD PRODUCTS DELIVERED

304,920

MOBILE BLOOD DRIVES

• rganized each year

(including blood drives in mobile units)

2,416

DONORS PER YEAR

(all types of donations)

173,244

COLLECTION METHODS

MOBILE BLOOD DRIVES CENTRES MOBILE UNITS

73% 20% 7%

FROM DONATION TO DISTRIBUTION

TRANSPORTATION

The blood bags and their samples are packed and sent to one of Héma-Québec’s laboratories.

STORAGE

Compliant products are labeled and stored, ready for shipment to hospitals.

DELIVERY

Products are delivered to hospitals. The blood components used vary depending on the patient.

ANALYSES

The blood samples collected during the donation are sent to the qualification laboratory to screen for infections.

SEPARATION OF WHOLE BLOOD

The blood is separated into its various components (red blood cells, platelets or plasma).

DONATION

The blood collection takes about ten minutes. In addition to the blood bag (450 ml), samples are collected for analysis.

generated over 357,039 visits to collection sites

Self-sufficiency rate in immunoglobulin relies on the generosity of our donors.

IMPROVING SELF-SUFFIENCY IN PLASMA INTENDED FOR MEDICATION MANUFACTURING

STABLE PRODUCTS

105,160

LITRES OF PLASMA

collected for purposes of manufacturing medications

SELF-SUFFICIENCY RATE

IN IMMUNOGLOBULIN

21.5%

IN 2017–2018 OF

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MEDICATIONS MANUFACTURED FROM PLASMA

STABLE PRODUCTS

427,822

Québec

STABLE PRODUCTS

delivered in 2017–2018

PRODUCTS MANUFACTURED BY PHARMACEUTICAL COMPANIES

under agreement with Héma-Québec

EXCLUSIVE DISTRIBUTION

for

50

Some

DIFFERENT PRODUCTS DISTRIBUTED

MANUFACTURED

from plasma collected by Héma-Québec

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including

DONATION

Plasma donations are made in donor centres, by appointment. The collection process lasts approximately 45 minutes.

FREEZING

Plasma is quickly frozen following

• collection. The faster you freeze it,

the more protein you can extract.

FROM DONATION TO DISTRIBUTION

ANALYSES

Collections are sent to the qualification laboratory. All donations are tested.

RETURN OF PRODUCTS TO HÉMA-QUÉBEC AND STORAGE

The finished products are then returned to Héma-Québec and stored, ready for shipment to hospitals.

FRACTIONATION

The plasma is sent to fractionation plants. These high-tech plants extract proteins from plasma and use them to make medications.

DELIVERY

Products are delivered to hospitals.

STEM CELL DONOR REGISTRY

STEM CELLS

45,690

to meet the needs of patients requiring a stem cell transplant

registered donors in Québec

32

MILLION

Héma-Québec is a part of a global network that includes

DONORS

Rosalie, cord blood recipient

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1

56

17

11

2

8

2

2

27

STEM CELLS

FIRST BANK

IN CANADA

9 PARTNER HOSPITALS

10,776

UNITS BANKED

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UNITS DISTRIBUTED IN 2017–2018

128 UNITS

DISTRIBUTED THROUGHOUT THE WORLD SINCE 2008

Internationally recognized expertise

PUBLIC CORD BLOOD BANK

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DONATION

Cord blood is collected at birth in partner hospitals.

TRANSPORTATION

Cord blood is transported to Héma-Québec.

QUALIFICATION

Cord blood is qualified based on strict criteria.

PROCESSING AND STORAGE

Cord blood is processed, frozen at −150 °C and stored for 15 years. The units of cord blood are made available through a world registry.

CALL AND RESEARCH

When our registry receives a call, we search for a compatible unit for a patient in need of a stem cell transplant.

TRANSPLANT

The patient receives the transplant.

• 150 °C

FROM DONATION TO TRANSPLANT

HUMAN TISSUES

Claudie-Ann, customer service agent (human tissues), handles musculoskeletal products.

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HUMAN TISSUES

HUMAN TISSUE BANK

5,451 5,464 1,008

Héma-Québec collects the following human tissues:

TISSUES DISTRIBUTED

to hospitals

DONOR REFERRALS DONORS WHO DONATED

in Québec

Ocular tissues (corneas, scleras) Heart valves Skin tissues Musculoskeletal tissues (tendons, bone chips, femoral heads...) Arterial tissues (abdominal aortas, arteries...)

IN 2017–2018

DONOR REFERRALS

Health professionals recommend donors to Héma-Québec.

TRANSPLANT

The surgeon transplants the

• tissues. One human tissue

donation can help up to 20 people.

CONSENT

A verification of the consent registries is made. Whether consent is registered

• r not, it is important for the donor to

inform his or her loved ones if he or she consents to the donation of human tissues, since they will be the ones who will speak on his or her behalf at the time of his or her death.

QUALIFICATION

Héma-Québec conducts a thorough evaluation to verify the donor’s eligibility.

COLLECTION

Héma-Québec performs the collection of human tissues.

PROCESSING AND STORAGE

The tissues are processed and stored until they are transplanted. Most tissues can be preserved for up to five years, with the exception of corneas that cannot be preserved beyond 14 days.

FROM DONOR REFERRALS TO TRANSPLANT

Mévick received mother’s milk at birth.

MOTHER’S MILK 16

MOTHER’S MILK

853

REGISTERED DONORS

11,767

BOTTLES DISTRIBUTED

IN 2017–2018

PUBLIC MOTHERS’ MILK BANK FOR VERY PRETERM INFANTS

DONATION

Héma-Québec supplies the bottles; mothers collect their milk at home and freeze it.

PICK-UP AND DROP-OFF POINT

Depending on the region, Héma-Québec collects the bottles at the donor’s home or the donor brings the milk to a drop-off point.

MICROBIOLOGICAL ANALYSES

Héma-Québec conducts tests

• n the unpasteurized milk to

ensure that it meets quality standards.

DONATION POOLING

Héma-Québec combines donations from several donors into one batch.

PASTEURIZATION

The milk is pasteurized to eliminate viruses and bacteria.

MICROBIOLOGICAL ANALYSES AND STORAGE

Héma-Québec tests the milk to ensure that it is safe for recipients; if the results are satisfactory, the milk is frozen and stored for a year.

DELIVERY

The milk is distributed to hospitals for very premature infants who cannot be breastfed by their mothers.

FROM DONATION TO DISTRIBUTION

SPECIALIZED LABORATORY SERVICES FOR HOSPITALS

1,715

ANALYSES

(donors in hospitals)

Screening for virological markers

4,704

testing requests received from hospitals

1,470

ANALYSES

(patients cases)

Complex cases in erythrocyte immunology

3,783

ANALYSES

(patients cases and donors)

Erythrocyte genotyping

• f blood groups

21,114

PHENOTYPED PACKED RED BLOOD CELLS

distributed

Phenotypimg

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Andy, donor The treatment of certain hereditary blood disorders and stem cell grafts require that the donor and recipient share a similar genetic makeup. Héma-Québec works closely with cultural communities to raise awareness about blood and stem cell donations.

The blood supply and the Stem Cell Donor Registry have to be representative

• f the makeup
• f Canada’s

population.

CHALLENGE OF DIVERSITY

12%

• f blood donors

are of non-Caucasian

• rigin

This proportion is 15% in the Québec population.

Priscille, recipient

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Donations confirmed positive according to the markers

ISO 15189

ISO 13485

NetCord-FACT

WMDA

(qualified member)

ASHI

ACCREDITATIONS

Héma-Québec makes every effort to provide the Québec population with biological products of human origin that are safe and

• f optimal-quality.

HEALTH CANADA AATB

• f Tissue Banks

RISK AND QUALITY MANAGEMENT: A CONSTANT CONCERN

PREVENTION:

AN IMPORTANT

ASPECT OF SAFETY

SAFETY ADVISORY COMITTEE

• representative. It monitors all existing

PATHOGENS

ARE BEING MONITORED:

bacteria, viruses or parasites that can be transmitted through blood

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2013–2014 2014–2015 2015–2016 2016–2017 2017–2018 Human immunodeficiency virus (HIV) 1 Hepatitis C virus (HCV) 22 12 12 13 14 Hepatitis B virus (HBV)* 16 14 5 10 20 Human T-cell lymphotropic virus (HTLV) 1 2 1 2 Syphilis 23 17 8 17 11 Total number of donations 277,956 276,473 276,956 305,201 301,900

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How does Héma-Québec intend to become a strategic partner

• f the Québec health system?

2017–2020 STRATEGIC PLAN

6 STRATEGIC ORIENTATIONS

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By comparing its practices with those of the leaders in its field, and taking the necessary steps to achieve its objectives for the benefit of its partners, and assuming its responsibility for the results

2

By keeping up with the latest developments in human biological products and being proactive so that the healthcare network can benefit from this expertise

3

By managing risks in an integrated manner at all levels of the organization in accordance with best practices

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By taking advantage of digital technology to improve its communication with its partners

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By developing the skills of its employees and mobilizing them by implementing a talent and succession management program

4

By modernizing and streamlining its processes in order to be more effective

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MOTHER’S MILK STEM CELLS STABLE PRODUCTS BLOOD PRODUCTS HUMAN TISSUES

2017–2018

www.hema-quebec.qc.ca