SERIES FOR HEALTHCARE PROVIDERS IN LMICS PROJECT ECHO ETIQUETTE - - PowerPoint PPT Presentation
SERIES FOR HEALTHCARE PROVIDERS IN LMICS PROJECT ECHO ETIQUETTE - - PowerPoint PPT Presentation
COVID-19 TELE-EDUCATION SERIES FOR HEALTHCARE PROVIDERS IN LMICS PROJECT ECHO ETIQUETTE Foundation of love and respect -Respond kindly rather than react if you disagree It is everybodys responsibility to keep ECHO a safe space
PROJECT ECHO ETIQUETTE
Foundation of love and respect
- Respond kindly rather than react if you disagree
It is everybody’s responsibility to keep ECHO a safe space Test your equipment ahead of time Introduce yourself before speaking Body signals can be distracting Avoid making noise (i.e. potato chips, shuffling papers, whispering, cell phones, loud bags, etc.) For questions during Q&A session use the “raise hand” function or chat box
PROJECT ECHO ETIQUETTE
Mute microphone when not speaking
- Left bottom corner of your screen
Remember to unmute before speaking Position webcam effectively to show your face if alone or to capture the whole group Have a light source from the front (Avoid being backlit) Test both audio and video Speak close to microphone IT issues? Send a message through chat/email
Pierre P. Massion, MD
Attending, Pulmonary Critical Care Medicine Service Vanderbilt University Medical Center, Nashville TN VA Medical Center, Nashville TN
COVID-19 TELE-EDUCATION SERIES FOR HEALTHCARE PROVIDERS IN LMICS
Respiratory Clinical Symptoms & Treatment
LEARNING OBJECTIVES
- Understand SARS CoV-2 infection; Recognize pathogenicity
- Presentation
- Diagnosis of Pneumonia Imaging and Pathology
- Challenges Pulmonary to ICU
- Priorities LMICs
- Key points/ References
- Questions:
Managing the COVID-19 Patient in the Critical Care Setting & Ventilation
COVID-19 TELE-EDUCATION SERIES FOR HEALTHCARE PROVIDERS IN LMICS
- Dr. Priscilla C. Hirst, MD, MSc
Montefiore New Rochelle Hospital
- Dr. Joseph J. Schlesinger, MD
Vanderbilt University Medical Center
LEARNING OBJECTIVES
- ACUTE RESPIRATORY DISTRESS SYNDROME
- RISK FACTORS FOR ARDS
- COVID-19 CARE ESSENTIALS
- COVID-19 RESPIRATORY SUPPORT ALGORITHM
- PRONE POSITIONING
- ANTICOAGULATION PROTOCOL
Multi-System Organ Failure and Sepsis
COVID-19 TELE-EDUCATION SERIES FOR HEALTHCARE PROVIDERS IN LMICS
Kyle Bruns DO, Kaitlyn Brennan DO, MPH Arna Banerjee MD, MMHC, FCCM, Kimberly Rengel MD 28/04/2020
LEARNING OBJECTIVES
- Review common organ dysfunction and initial treatment in ICU patients with sepsis
and COVID 19
- Understand organ dysfunction specific to COVID 19 infection
- Formulate optimal treatment plans based on your hospital’s capabilities
Clinical Features and Management of Cardiovascular Disease (CVD) in COVID 19
COVID-19 TELE-EDUCATION SERIES FOR HEALTHCARE PROVIDERS IN LMICS
Henry Okafor, MD, FACC Director of Vanderbilt-Meharry Cardiology May 1, 2020
DISCLOSURES
- The speaker has no significant financial conflicts of interest to disclose
LEARNING OBJECTIVES
- Understand the spectrum of cardiovascular disease in Covid-19
- Review the clinical features of CVD in Covid-19
- Discuss the approach to therapeutic decisions in CVD complications of Covid-19
- Highlight potential adaptations in low resource settings
CASE PRESENTATIONS OF CVD IN COVID-19
CASE 1
- 55 y/o man with a h/o HTN, DM-2, severe NICM/HFrEF
(prior LVEF was <20%) and non-obstructive CAD.
- Presents with 1 week h/o progressive dyspnea on mild
exertion and 3 days of exertional angina.
- Bp -150/101, HR-94, T
- 98.1F, RR-22, O2sat – 96-98% RA.
- Positive bibasilar crackles, elevated JVD, S3 gallop and 2+
bilat pitting edema.
CASE 1 TESTS
EKG LABs CXR 2D-ECHO
- NSR w/
PACs
- LAD
- NSST
- T
wave changes
- Trop 1.07
- p-BNP 22K
- Cardiomegaly
- Pulmonary
congestion
- No
pneumonia
- Biventricular
failure
- LVEF <20%
- Grade 3 DD
- Small PE, no
tamponade
CASE I CONTD
- Clinical improvement with iv
diuresis
- Temp spike to 101.7F on Day 3
- Progressive hypoxia requiring
increasing oxygen supplementation,
- Septic w/u initiated including for
SARS COV2
- Elevated inflammatory markers –
CRP, fibrinogen, ferritin and D-Dimer
- COVID-19 resulted positive on Day 8
- Treated with Azithromycin x 5 days,
avoided HCQ due to prolonged baseline QT
- Hypoxia and fever resolved and
patient discharged on Day 15
CASE 2
- 68 y/o woman with h/o HTN, DM-2 was hospitalized 10
days after initially testing positive for Covid-19, required mechanical ventilation for respiratory failure.
- Day 5 on the vent, she became acutely more tachycardic
and hypotensive requiring vasopressors.
- Septic w/u initiated although she was already on HCQ
and Azithromycin.
CASE 2 CONTD
- Stat 2 d-Echo revealed severely impaired LV systolic
function with severe global hypokinesis and LVEF of 25- 30%.
- Inotropic support with low dose dobutamine was
initiated and hemodynamics stabilized over 24-48hours.
- Repeat echo after 7 days showed almost normal LVEF of
45-50%.
COVID-19 EPIDEMIOLOGY
- COVID-19 pandemic caused by SARS – COV2.
- Primarily respiratory disease
- Has extensive interaction with CVS.
– Patients with CVD are at higher risk of getting infected – Outcomes are worse in CVD patients
- CVD complications are common in patients with COVID-19 even in the absence of premorbid
CVD.
- Some of the current treatment for Covid-19 may cause CVD complications such as arrhythmias.
Date of download: 4/11/2020
From: Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)
JAMA Cardiol. Published online March 27, 2020. doi:10.1001/jamacardio.2020.1017 Mortality of Patients With Coronavirus Disease 2019 (COVID-19) With/Without Cardiovascular Disease (CVD) and With/Without Elevated Troponin T (TnT) Levels Figure Legend:
SPECTRUM OF CVD IN COVID-19
Pre-existing CVD SARS-COV-2 related Treatment-related Heart Failure/CMP Cardiogenic shock/HFrEF Arrhythmias Coronary Artery Disease Acute MI, Myocarditis Cardiotoxicity Hypertension Arrhythmias, CMP Arrhythmias Thromboembolism
Date of download: 4/27/2020
From: Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China
- JAMA. 2020;323(11):1061-1069. doi:10.1001/jama.2020.1585
PATHOGENESIS
- SARS-CoV2 - single-strand RNA
- enters human cells mainly by binding
the angiotensin converting enzyme 2 (ACE2)
- highly expressed in lung alveolar cells,
cardiac myocytes, the vascular endothelium, and other cells.
- Leads to a mild to moderate viral
illness or progress to systemic inflammatory response syndrome, acute respiratory disease syndrome (ARDS), multi-organ involvement, and shock
MECHANISMS OF MYOCARDIAL INJURY
CVD MANAGEMENT PRINCIPLES IN COVID-19
ACC recommendations:
- Establish protocols for effective clinical triage, diagnosis, and isolation of
Covid-19 patients with CVD or CVD complications.
- Individualize and limit diagnostic testing to essential tests that could
facilitate management.
- Consider point of care testing where available.
- Universal precautions including masks for both patient and healthcare
worker.
- Use of Telemedicine where possible
ACS MANAGEMENT IN COVID-19
- Universal precautions including masks for patients and healthcare workers.
- Early Testing for COVID-19
- STEMI
- Consider Fibrinolytic Therapy
- High risk primary PCI in dedicated COVID-19 Cath lab in full PPE
- Unstable Angina and NSTEMI
- Medical Therapy and consider CT Coronary angiogram for high risk patients.
Bedside clinical assessment
- cold extremities
- Hypotension
- JVD
- use POCUS vs 2 D-echo
GDMT including ACEI/ARBs are recommended.
If in cardiogenic shock, consider
- Inotropic support and vasopressors
- Dobutamine
- Nor-epinephrine
- Vasopressin
- Extracorporeal Membrane Oxygenation
(ECMO)
- Veno-Venous in intractable respiratory
failure
- Veno-Arterial in cardiogenic shock
HEART FAILURE AND CARDIOGENIC SHOCK IN COVID-19
THROMBOEMBOLISM IN COVID-19
PREVENTION AND MANAGEMENT OF THROMBOSIS IN COVID-19
- Assess for risk factors
- Pre-existing need for anticoagulation
- Age
- Bed-ridden status (Stasis)
- Disease severity: Inflammatory
response, endothelial injury
- Hemostatic abnormalities: Elevated D-
dimer, DIC, High Procalcitonin
- Confirmed DVT/PE in COVID-19
- Prophylaxis per usual protocol
- Therapeutic anticoagulation
with low molecular weight vs unfractionated Heparin
MALIGNANT ARRHYTHMIAS
- Mitigate risk by:
- check baseline EKG and avoid QT prolonging drugs if QTC >500ms
- correct electrolyte abnormalities (K+, Mg and Ca) prior to treatment
- caution with diuretics
- permissive tachycardia (HR of 90-110 bpm)
- DCCV if hemodynamic instability occurs
SUMMARY
- Diverse manifestations of CVD in Covid-19
- Establish, rehearse and follow protocols
- Maintain consistent universal precautions
- Tailor care to individual needs
- Avoid unnecessary testing
- Adapt care to available resources I
- Use Telemedicine where possible
VanderbiltHeart.com
QUESTIONS?
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