SLIDE 1
Sclerochoroidal Calcification
Andrew Brown BARS Conference September 2016
SLIDE 2 Case Presentation
- 62 year old white Caucasian female
- Newly diagnosed T2DM – 1st Screening
- No visual symptoms
- Regularly attends the renal physicians –
Gitelman’s Syndrome
- Referred by O.O. 10 years ago following a
routine EE – seen in HES and discharged
SLIDE 3
Right Eye Macula Centred
SLIDE 4
Left Eye Macula Centered
SLIDE 5
- Clinical Features of Sclerochoroidal
Calcification
- Causes
- Differential diagnosis
- Learning points
SLIDE 6 Sclerochoroidal Calcification
- Benign intra-ocular deposition of calcium
- Commences within the sclera and causes
secondary rarefaction of the choroid
- Rod dysfunction (on ERG testing)
- Detected as incidental finding
- Older white patients (median age 70 years)
- Unilateral? Bilateral?
SLIDE 7 Sclerochoroidal Calcification
- Multiple yellow-white sub-retinal lesions
- Superior to supero-temporal retinal arcade
- Mid-peripheral (between arcade and equator)
- Minimally elevated
- RPE atrophy
- May be complicated by choroidal neovascular
membranes and sub-retinal fluid
SLIDE 8 Causes
- Idiopathic
- Hypercalcaemia
Hyperparathyroidism Vitamin D intoxication Sarcoidosis
Gitelman syndrome Bartter Syndrome
Familial articular chondrochalcinosis
SLIDE 9 Differential Diagnosis
- Choroidal Metastasis
- Choroidal Melanoma
- Choroidal Naevus
- Choroidal Osteoma
SLIDE 10 Investigations
- OCT – EDI
- OCT – Autofluorescence
- Ophthalmic ultrasound
- Optos Widefield imaging
SLIDE 11
SLIDE 12
SLIDE 13
SLIDE 14
Sclerochoroidal calcification
SLIDE 15
Sclerochoroidal calcification
SLIDE 16
Choroidal Metastasis
SLIDE 17
Choroidal Metastasis
SLIDE 18
Choroidal Melanoma
SLIDE 19
Choroidal Melanoma
SLIDE 20
Choroidal Melanoma
SLIDE 21
SLIDE 22
Choroidal Osteoma
SLIDE 23
Choroidal Naevus
SLIDE 24 Learning Points
- Yellow white mid-peripheral lesions
- White adults
- Asymptomatic
- Important mimicking disease
- Should be screened for metabolic disorders
- Occasionally have sight threatening
complications
SLIDE 25
Thank you
Any Questions?