SLIDE 1 Case Presentation Pericallosal lipoma with agenesis
- f corpus callosum
- Dr. Anusha.R,
2nd year post graduate, Department Of Radio- Diagnosis
SLIDE 2
Clinical details
17 year old male patient was referred from Miryalguda to the department of Radio- Diagnosis for evaluation of seizures using MRI Brain.
SLIDE 3
Presenting complaints
Patient was suffering from seizure’s since childhood. Past history : No history of any head trauma, tuberculosis, diabetes, no history of any fever with rash or any other diseases. Addictions : no history of any smoking or alcohol consumption.
SLIDE 4 Investigations
- Routine Haematological investigations were
unremarkable.
- Chest X-ray showed normal study.
- Ultrasound abdomen showed no sonological
abnormality.
- All the above investigations were done outside.
SLIDE 5
MRI BRAIN FINDINGS
SLIDE 6 T1W Mid Sagittal image showing Complete absence of corpus callosum & absent cingulate gyrus.
Normal T1 Mid Sagittal image
SLIDE 7
T1 Para Saggital & axial showing hyperintense lesion in anterior pericallosal region
SLIDE 8
T1 Coronal - VIKING HELMET SIGN – pointed upturned lateral ventricles with high riding 3rd ventricle
SLIDE 9 T2 axial images showing parallel
- rientation & widely separated lateral
ventricle – RACING CAR SIGN
SLIDE 10
T2 Axial Images show dilated occipital horns COLPOCEPHALY – RABBIT EAR SIGN
SLIDE 11
T2 STIR showing Fat suppression of anterior pericallosal lesion – suggestive of lipoma
SLIDE 12
SWI, Phase Contrast images show blooming & hyperintensity in the periphery of pericallosal lipoma- s/o calcification
SLIDE 13
Axial CT Brain showing fat density(-100 HU) lesion with peripheral calcification in anterior pericallosal region
SLIDE 14
CT Brain bone window - peripheral bracket shaped calcification
SLIDE 15
AP RADIOGRAPH SKULL - BRACKET SIGN
SLIDE 16 Imaging findings
MRI Brain : Complete absence of corpus callosum
- Parallel, non converging lateral ventricles
- Dilated occipital horns of lateral ventricles
- T1,T2 hyperintense,Extra-axial lobular lesion seen
in the midline in the anterior pericallosal region with suppression on STIR sequences & peripheral blooming on SWI CT BRAIN :
- extra- axial fat density lesion seen in midline in
anterior pericallosal region with peripheral calcifications with complete absence of corpus callosum.
SLIDE 17
Differential diagnosis: for pericallosal lipoma 1.Intracranial dermoid cyst : usually 20-30 HU, signal intensity is more heterogenous, no associated malformations, calcification is common 2.Intracranial teratoma: more heterogenous in appearance, show solid & cystic components, solid component shows contrast enhancement.
SLIDE 18
Final Diagnosis:
Tubulonodular variety of pericallosal lipoma with peripheral calcifications & complete agenesis of corpus callosum.
SLIDE 19
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