SARS-CoV-2 Virus and COVID-19 Disease 1 Understanding of Disease - PowerPoint PPT Presentation

SARS-CoV-2 Virus and COVID-19 Disease 1

Understanding of Disease Systems – Foundational Funding Programs 2

Dear Colleague Letter on COVID-19 (NSF 20-052) 3,500 3,115 • Model and understand 3,000 spread 2,500 • Inform and educate about 2,000 transmission and prevention 1,500 • Develop process and actions 1,000 558 to address global challenge 500 98 63 0 Inquiries RAPID Pending Awards to Proposals Awards Date 3

COVID-19 RAPIDs – Thematic Overview BIO Biology of the virus CISE Predicting the spread EHR Detecting the virus ENG Limiting the spread GEO Impact of behavior MPS Impact on society SBE 4

COVID-19 RAPIDs – Examples Biophysical characterization of the native SARS-CoV-2 virion by atomistic simulations 5

COVID-19 RAPIDs – Examples Biophysical characterization of the native SARS-CoV-2 virion by atomistic simulations Coronavirus persistence, transmission, and circulation in the environment 6

COVID-19 RAPIDs – Examples Coronavirus persistence, transmission, and Biophysical characterization of the native circulation in the environment SARS-CoV-2 virion by atomistic simulations Development of Rapid POC SARS-2019-nCoV LAMP-OSD Assay System 7

COVID-19 RAPIDs – Examples Coronavirus persistence, transmission, and Biophysical characterization of the native circulation in the environment SARS-CoV-2 virion by atomistic simulations Accelerated Testing for COVID-19 using Group Testing Development of Rapid POC SARS-2019-nCoV LAMP-OSD Assay System 8

COVID-19 RAPIDs – Examples Coronavirus persistence, transmission, and Biophysical characterization of the native circulation in the environment SARS-CoV-2 virion by atomistic simulations On-mask Chemical Modulation of Respiratory Droplets Accelerated Testing for COVID-19 Development of Rapid POC SARS-2019- using Group Testing nCoV LAMP-OSD Assay System 9

COVID-19 RAPIDs – Examples Coronavirus persistence, transmission, and Biophysical characterization of the native circulation in the environment SARS-CoV-2 virion by atomistic simulations Uncertain Risk and Stressful Future: A National Study of the COVID-2019 Outbreak in the U.S . On-mask Chemical Modulation of Respiratory Droplets Accelerated Testing for COVID-19 Development of Rapid POC SARS-2019- using Group Testing nCoV LAMP-OSD Assay System 10

https://www.nsf.gov/news/special_reports/coronavirus/ 11

https://www.nsf.gov/news/factsheets/NSF-Funded Research COVID-19 Fact Sheet.pdf 12

Learnings: Preparing for the Next Pandemic From reactive to predictive; segmented to interdisciplinary and coordinated 13