RTI International Wearable Sensor Research MEDICAL, BIOMEDICAL & - PowerPoint PPT Presentation

RTI International Wearable Sensor Research MEDICAL, BIOMEDICAL & BIODEFENSE: SUPPORT TO THE WARFIGHTER SYMPOSIUM Kristin H. Gilchrist, Ph.D www.rti.org RTI International is a registered trademark and a trade name of Research Triangle Institute.

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Novel Applications of COTS Wearables Wearable Sensors Actionable Information  Commercially available sensors can be leveraged for applications beyond the marketed purpose  Applications range from health to education  Combination of signal processing and unique algorithms provide actionable information  Algorithms can be developed that are compatible with continuous monitoring, real-time results, and integration into compact hardware

Real-Time Seizure Detection  RTI in collaboration with Children’s National Medical Center developed a real-time seizure detection system.  Caregiver intervention is the sole method of mitigating seizure-related adverse events.  Seizure detection is based on autonomic nervous system activity reflected in heart and respiratory measures  Uses an unobtrusive COTS ECG sensor  Preliminary work enabled with internal funding which helped secure an NIH grant to further development.  Approach demonstrated promise for accurate detection of a range of seizure types and is ready for further development by a commercial partner.

Mild Traumatic Brain Injury (mTBI) Diagnostic  Need objective measures for diagnosing mTBI (concussion) amenable to low-cost operation in the field.  Recently completed pilot study at Womack Army Medical Center with funding via AMEDD Advanced Medical Technology Initiative.  COTS wearable ECG sensor to identify signatures of mTBI Predictive mTBI Model from Pilot Study based on heart rate responses to posture changes.  Distinguished mTBI subjects within 3 days of injury (n=31) from healthy controls (n=32) with up to 90% sensitivity. 90% sensitivity / 69% specificity  Method amenable to implementation in real time on a 87% sensitivity / 81% specificity tablet or smartphone.  Enables complete test to result in about 5 minutes by minimally trained persons in a field setting. * Publication in preparation.

Presymptomatic Illness Detection  Two active DoD funded projects to detect illness prior to symptom development.  For an individual, earlier intervention can improve outcomes.  For populations, the time to detect disease outbreaks or threat exposures can be significantly shortened.  Continuous monitoring by COTS sensors without interruption to normal activity.  Sophisticated algorithms distinguish illness from confounding factors which impact wellness.

RTI International Kristin H. Gilchrist, PhD kgilchrist@rti.org 919.248.1456 10