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RTI International Wearable Sensor Research

MEDICAL, BIOMEDICAL & BIODEFENSE: SUPPORT TO THE WARFIGHTER SYMPOSIUM

Kristin H. Gilchrist, Ph.D

RTI International

RTI International is an independent, nonprofit research institute dedicated to improving the human condition. We combine scientific rigor and technical expertise in social and laboratory sciences, engineering, and international development to deliver solutions to the critical needs of clients worldwide.

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Practice Areas

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Technology Advancement & Commercialization (TAC)

RTI’s Technology Advancement & Commercialization (TAC)

Delivering on the RTI Mission

Improving the human condition through innovation and translational science and engineering

Develop client-focused solutions

• Health
• Energy
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Offer specialized facilities and laboratories Deploy novel technologies Commercialize IP

Novel Applications of COTS Wearables

• Commercially available sensors can be leveraged for applications beyond the marketed

purpose

• Applications range from health to education
• Combination of signal processing and unique algorithms provide actionable information
• Algorithms can be developed that are compatible with continuous monitoring, real-time

results, and integration into compact hardware Actionable Information Wearable Sensors

Real-Time Seizure Detection

• RTI in collaboration with Children’s National Medical

Center developed a real-time seizure detection system.

• Caregiver intervention is the sole method of mitigating

seizure-related adverse events.

• Seizure detection is based on autonomic nervous

system activity reflected in heart and respiratory measures

• Uses an unobtrusive COTS ECG sensor
• Preliminary work enabled with internal funding which

helped secure an NIH grant to further development.

• Approach demonstrated promise for accurate detection
• f a range of seizure types and is ready for further

development by a commercial partner.

Mild Traumatic Brain Injury (mTBI) Diagnostic

• Need objective measures for diagnosing mTBI

(concussion) amenable to low-cost operation in the field.

• Recently completed pilot study at Womack Army Medical

Center with funding via AMEDD Advanced Medical Technology Initiative.

• COTS wearable ECG sensor to identify signatures of mTBI

based on heart rate responses to posture changes.

• Distinguished mTBI subjects within 3 days of injury (n=31)

from healthy controls (n=32) with up to 90% sensitivity.

• Method amenable to implementation in real time on a

tablet or smartphone.

• Enables complete test to result in about 5 minutes by

minimally trained persons in a field setting.

90% sensitivity / 69% specificity 87% sensitivity / 81% specificity

* Publication in preparation.

Predictive mTBI Model from Pilot Study

Presymptomatic Illness Detection

• Two active DoD funded projects to

detect illness prior to symptom development.

• For an individual, earlier intervention

can improve outcomes.

• For populations, the time to detect

disease outbreaks or threat exposures can be significantly shortened.

• Continuous monitoring by COTS

sensors without interruption to normal activity.

• Sophisticated algorithms distinguish

illness from confounding factors which impact wellness.

RTI International

Kristin H. Gilchrist, PhD kgilchrist@rti.org 919.248.1456

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