Reducing mortality and severe morbidity in the first 3 years of life - - PowerPoint PPT Presentation

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reducing mortality and severe morbidity in the first 3
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Reducing mortality and severe morbidity in the first 3 years of life - - PowerPoint PPT Presentation

Sep 25, 2023 176 likes •229 views

Corinne Martin Christle GRAS- Franois Julie Romain Barbara Andreas Robert Muhamed-Kheir Albert Magali Corinne Romain Marie-Aline Florentia Sophie Sabine Mathie LEVY CHALUMEAU LE GUEN ANGOULVANT TOUBIANA GUEDJ HEUDE

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SLIDE 1

Reducing mortality and severe morbidity in the first 3 years of life

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Martin CHALUMEAU Corinne LEVY Christèle GRAS- LE GUEN Robert COHEN Romain GUEDJ Andreas WERNER Muhamed-Kheir TAHA Marie-Aline CHARLES Barbara HEUDE François ANGOULVANT Florentia KAGUELIDOU Magali LEMAITRE Romain LECOMTE Albert FAYE Corinne ALBERTI Julie TOUBIANA Christine LEBRETON Stéphane BONACORSI Emmanuelle VARON Milena HASAN Romain BASMACI Jean GASCHIGNARD Sylvain BRISSE Emmanuel GRIMPREL Ricardo CARBAJAL Vincent GAJDOS Loic DE PONTUAL Sandra BISCARDI Jérémie COHEN Bruno FRANDJI Sophie MULLER Shania KHAN Fabien FENOUILLET Christiane DINTER Elise LAUNAY Sabine PLANCOULAINE Mathie LORROT Enora LE ROUX

www.childfhu.com

Yacine REFES

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SLIDE 2

Alarming mortality rates in young children in France

Mortality rates < 3 years old/ 1000 live births

1 2 3 4 5 6 7 8

2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

Helpful for other countries with ≥ rates New knowledge and tools ≈ 1200 avoidable deaths/ y + additional avoidability? To reduce < 3 morbimortality, initial focus on improving the prevention, diagnosis, and management of: acute infections, sudden unexpected infant death, and child physical abuse

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SLIDE 3

+ patients voice: La Voix de l’Enfant, Audrey Méningite, Naitre et Vivre, Sa Vie

Academic Research teams

  • Epidemiology
  • Bacteriology
  • Multi-Omics
  • Human motivation

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CHILD initiative partners

Private partners

  • Biomarkers
  • Drug data hub and trials
  • Medical software solutions
  • Scientific publishing
  • Health digital learning
  • Vaccines

6 Clinical teams

  • Polyvalent pediatricians
  • Hospital + community
  • Regional + national level

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SLIDE 4

A multifaceted approach needed

Health and health practices epidemiology:

  • indicators on health and

healthcare practices

  • by parents and healthcare

professionals (HP)

  • their determinants (including

social inequalities)

Massive implementation strategies:

  • digital health learning tools and trials
  • modify knowledge-attitudes-practices (KAP) of parents

(disadvantaged ones) and HPs

Basic knowledge production:

  • large clinical trials
  • risk stratification modelling
  • biomarker discovery / validation

WP 2 WP 3 WP 4

Child health data hub: e-portal of available biobanks, databases, computational skills

WP 1