reducing mortality and severe morbidity in the first 3
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Reducing mortality and severe morbidity in the first 3 years of life - PowerPoint PPT Presentation

Sep 25, 2023 •176 likes •224 views

Corinne Martin Christle GRAS- Franois Julie Romain Barbara Andreas Robert Muhamed-Kheir Albert Magali Corinne Romain Marie-Aline Florentia Sophie Sabine Mathie LEVY CHALUMEAU LE GUEN ANGOULVANT TOUBIANA GUEDJ HEUDE

  1. Corinne Martin Christèle GRAS- François Julie Romain Barbara Andreas Robert Muhamed-Kheir Albert Magali Corinne Romain Marie-Aline Florentia Sophie Sabine Mathie LEVY CHALUMEAU LE GUEN ANGOULVANT TOUBIANA GUEDJ HEUDE WERNER COHEN TAHA FAYE LEMAITRE ALBERTI LECOMTE CHARLES KAGUELIDOU MULLER PLANCOULAINE LORROT www.childfhu.com Reducing mortality and severe morbidity in the first 3 years of life Emmanuelle Jérémie Jean Stéphane Christine Sylvain Vincent Sandra Emmanuel Loic Milena Romain Bruno Shania Ricardo Fabien Enora Elise Christiane Yacine VARON COHEN GASCHIGNARD BONACORSI LEBRETON BRISSE GAJDOS BISCARDI REFES GRIMPREL DE PONTUAL HASAN BASMACI FRANDJI KHAN CARBAJAL FENOUILLET LE ROUX LAUNAY DINTER 1

  2. Alarming mortality rates in young children in France Mortality rates < 3 years old/ 1000 live births 8 7 6 Helpful for other countries with ≥ rates 5 4 New ≈ 1200 avoidable deaths/ y 3 knowledge and tools + additional avoidability? 2 1 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 To reduce < 3 morbimortality, initial focus on improving the prevention, diagnosis, and management of: acute infections, sudden unexpected infant death, and child physical abuse

  3. CHILD initiative partners 8 11 6 Clinical teams Academic Research Private partners teams - Polyvalent pediatricians - Epidemiology - Biomarkers - Hospital + community - Bacteriology - Drug data hub and trials - Regional + national level - Multi-Omics - Medical software solutions - Human motivation - Scientific publishing - Health digital learning - Vaccines + patients voice: La Voix de l’Enfant, Audrey Méningite, Naitre et Vivre, Sa Vie

  4. A multifaceted approach needed WP 1 Child health data hub: e-portal of available biobanks, databases, computational skills WP WP Health and health practices Basic knowledge production: 3 2 - large clinical trials epidemiology: - risk stratification modelling - indicators on health and - biomarker discovery / validation healthcare practices - by parents and healthcare WP Massive implementation strategies: professionals (HP) 4 - digital health learning tools and trials - their determinants (including - modify knowledge-attitudes-practices (KAP) of parents social inequalities) (disadvantaged ones) and HPs

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