Prevagen Professional Training Webinar! Corrina McVay Healthcare - - PowerPoint PPT Presentation

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Corrina McVay

Healthcare Accounts Manager

Welcome to the Prevagen Professional Training Webinar!

Aging Concerns in the U.S.

“What is your biggest fear about aging?”  Losing mental/brain capacity  Running out of money  Being a burden on loved ones  Restricted mobility  Heart Attack  Death of a spouse  Arthritis

* Natural Marketing Institute’s 2008 Healthy Aging/Boomer General Population Survey

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“Healthy Aging Survey”

Aging Concerns in the U.S.

“What is your biggest fear about aging?” Losing mental/brain capacity  Running out of money  Being a burden on loved ones  Restricted mobility  Heart Attack  Death of a spouse  Arthritis

* Natural Marketing Institute’s 2008 Healthy Aging/Boomer General Population Survey

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Survey of Gen Y, Gen X, Baby Boomers, and Matures

Likelihood of Using a Memory Supplement

* Natural Marketing Institute’s 2008 Healthy Aging/Boomer General Population Survey

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20 40 60 Actual Use Likely Use to Prevent Likely Use to Treat

Unmet need!

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How Can We Close the Gap?

Quincy Bioscience

• Quincy founded in 2004
• Discovered apoaequorin for

human use - patented

• Developed Prevagen in 2007
• Research-based

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Headquarters - Madison, WI Production - Middleton, WI

Apoaequorin Story

(short version)

• Discovered in 1962
• Luminescent calcium-binding protein (CaBP)
• Biological “flashlight”
• Nobel Prize for Chemistry in 2008

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• Apoaequorin binds calcium ions

Inouye, Satoshi, et al. “Cloning and sequence analysis of cDNA for the luminescent protein Apoaequorin.” Proceedings of the National Academy of Sciences, USA. Vol. 82 (May 1985): pp. 3154-3158.

• Apoaequorin is non-toxic

Blinks, John. “Use of photoproteins as Intracellular Calcium Indicators.” Environmental Health Perspectives Vol. 84 (1990): pp. 75- 81.

• Apoaequorin does not interfere with other cellular

functions

Miller, Al, et al. “Imaging CA2+ with Apoaequorin using a photon imaging detector.” Methods in Cell Biology (1994): 40:305-338.

• Apoaequorin is similar in amino acid sequence to

endogenous CaBP’s

Moncrief, N.D. “Evolution of EF-hand calcium-modulated proteins.” Journal of Molecular Evolution. Vol. 30, Issue 6 (1990): pp. 522- 562.

Apoaequorin Facts

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The “Other” Calcium

• 99% of calcium in bones and teeth, 1% of

calcium in our nervous system

• Ionized calcium is a “ubiquitous 2nd

messenger”

• Neuron signaling cascades:

– Neurotransmitter release – Enzyme activation – Gene expression – Mitochondrial function

• Must be tightly regulated

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Calcium Management

VGC GCC

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Calcium Dysregulation

Calcium Binding Proteins

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Iacopino Anthony M, Christakos Sylvia (1990) Specific Reduction of calcium-binding protein gene expression in aging. Proc. Natl. Acad. Sci.

• Vol. 87, pp.4078-4082.

Calmodulin Calbindin Calretinin Parvalbumin

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Cognitive Issues in Aging

“…subtle changes in Ca2+ homeostasis or in the state of various Ca2+-dependent processes, which occur in aging can have significant functional consequences.”

Society for Neuroscience

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Prevagen Brands

• 10mg or 20 mg apoaequorin
• Safe for any age
• Now Chewables
• 40mg apoaequorin
• Distributed only by

Healthcare Professionals

• For greater memory concerns

First & only ingredient of its kind

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Who Should Try Prevagen?

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• Memory lapses

inconvenient

• Family history
• Younger patients
• 10mg / 20mg
• Memory lapses

interfering

• “Loading dose”
• 40mg

Madison Memory Study

• Double blind, placebo

controlled

• adults 40+ years old
• 90 days, n=218
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Madison Memory Study

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Groton Maze Learning Task Recall p=<.05

Madison Memory Study

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Groton Maze Learning Task Recall p=<.05

Madison Memory Study Results

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 Executive function

 Learning  Short-term memory  Shopping list recall

Statistically significant improvement over 90 days in:

Patient Support

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We provide free tools to help your patients!

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Patient Support

www.bettermemorycenter.com

Patient Support

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Clinic Poster Brain Health Guide

Awareness Education

What Do Patients Notice?

“Over the last few months I have been taking Prevagen and I’ve experienced several improvements. Here are a few of the things I’ve noticed: Thinking/Cognition

• I have more energy during the day and can concentrate longer on tasks.
• I’m more fluent when I speak. I can “find” the right word more quickly.
• My reading comprehension is better.
• I feel like a radio that’s finely tuned; I feel “clear” headed

Fatigue

• I have more energy, perhaps because I’m sleeping through the night. I used to wake up

several times a night to look at the calendar.

• I don’t “run out of gas” during the day and rarely take a nap, (I used to nap often.)
• I rarely feel tired – a huge change!”

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• Shelley Schwarz, 61 yrs old

(email sent to company)

Prevagen Results

“When people are experiencing the start

• f memory loss such as having difficulty

remembering why they walked from one room to the next, I suggest they take Prevagen.” Henry Matick, D.O. Matick Neurology Clinic

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Quality Production – cGMP

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Fermentation Freeze Drying Encapsulation & bottling Purification & Quality Control

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Patent pending.

Prevagen Professional

• Improves Cognitive Function
• Unique mechanism of action
• Proven safe & well-tolerated
• Contains no common allergens
• Manufactured in Wis – no jellyfish

harmed in the process 

• Exclusive to Healthcare Professionals

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Ordering Information: (888) 895-6463

www.PrevagenPro.com

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Thank You!

Wholesale:

$54.00 ea 30ct $46.29 ea 30ct (1 Case = 7 bottles) Suggested Retail: $89.95 ea 30ct B2G1 50% off - $224.85

Prevagen Professional Pricing

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