Preparticipation Sports Physical Cardiac Secrets When to order an - - PowerPoint PPT Presentation

Preparticipation Sports Physical “Cardiac Secrets” When to order an EKG and/or Echocardiogram

David Drossner, MD Pediatric Cardiology Palm Beach, FL

Disclosures

• I wish, but none

Goal

Ordering an EKG and/or echocardiogram as an adjunct to the preparticipation sports physical exam

Objectives

• 1. Define Sudden Cardiac Arrest and etiologies
• 1. Discuses top 3 cardiac conditions leading to

SCA

• 1. Should all pediatric patients undergo EKG

screening in addition to the PPE?

What is Sudden Cardiac Arrest?

What is Sudden Cardiac Arrest

Sudden cessation of cardiac activity/pumping function resulting in hemodynamic collapse SCA ≠ Heart attack

Putting it in perspective

• SCA leading cause of death in school aged

atheletes

• 2,000 peds patients/year (at least)
• Low survival rate
• Under reporting
• Often as no warning signs
• 50% first symptom will be SCA

Comparison of published data from the US National Registry with the Parent Heart Watch database

1990 1st edition 1992

12 point American Heart Assoc 1996

14 Element AHA 2014

Preparticipation Physical Exam

AAP guidelines

“Identify medical problems with risks of life- threatening complications during participation”

PPE 5th Edition

PPE Florida Form

 Hypertrophic Cardiomyopathy  Coronary Abnormalities  Channelopathies

HCM

• 1/500 persons in the general

population

• 750K estimated to be affected by

HCM

– 100,000 diagnosed – Under recognition

HCM- A family disease

• Autosomal Dominant
• All about communication

– Abnormal thickening – ICD – Death during sport – Heart transplant – Heart problems at an early age

HCM- Presenting Symptoms

–Chest Pain –Presyncope/synco pe –Palpitations –SCA

HCM- explaining the symptoms Context matters!

HCM-physical exam

• Cardiac murmur (53%)
• Harsh systolic murmur
• Dynamic auscultation

– Valsalva – Standing preload

HCM and ambulatory testing

EKG can be abnormal in over 90% of HCM patients*

*Ryan MP, Cleland JG, French JA, et al. The standard electrocardiogram as a screening test for hypertrophic cardiomyopathy. Am J Cardiol

1995;76:689–94. 48 Maron BJ, Roberts WC, Epstein SE. Sudden death in hypertrophic cardiomyopathy: a profile of 78 patients. Circulation 1982;65:1388–94. Rowin EJ, Maron BJ, Appelbaum E, et al. Significance of false negative 49 electrocardiograms in preparticipation screening of athletes for hypertrophic

Coronary Artery Anomalies

• 0.1-1% in adult and pediatric population
• No suggested to be a familial/genetic disease
• No physical exam findings
• EKGs are normal
• All about the history

Normal Coronary Artery Anatomy

Anomalous Right CA from Left Anomalous Left CA from Right

Sudden Cardiac Arrest Mechanism of action

• Limited coronary reserve

– Ostial stenosis – Compression of anomalous coronary artery intramurally or between great vessels

• Exercise and SCA

– Recreational >competitive

Clinical Presentation

• Incidental diagnosis
• SCA or aborted SCA
• Chest pain with physical activity (ischemic)
• Other symptoms with exertion

Anomalous Coronary Artery and Exercise All about history

Arrhythmia Disorders

• Wolf Parkinson White Syndrome
• Long QT syndrome
• Ventricular Ectopy

WPW

• 0.25% of the population

– Bit higher in 1st degree family members

• Incidence of SCD in asymptomatic patient is

low 0.13%/year

• Symptomatic patients risk for SCA 0.25%/year

– 3-4% lifetime risk

WPW- presenting symptoms

• Palpitations (SVT)
• Syncope
• SCA (rare)
• No physical exam

findings

WPW and EKGs

WPW

Worst case Scenario

Long QT Syndrome

• Disorder of ventricular myocardial

repolarization

• 1/2000 live births
• Average age at 1st symptom is 12 years

– Increased # of asymptomatic Dxs

A Family Disease

• Autosomal Dominant
• Autosomal recessive
• Key Questions

– Unexplained

• SCD <40
• MVA
• Drownings

Long QT syndrome presenting signs

• Syncope
• Seizures
• SCA
• Context matters!

– Swimming, diving, acute arousal, emotional stress – Physical exertion

Long QT Syndrome

Premature Ventricular Contractions

CPVT

• Familial disease
• Arrhythmia disorder
• Bidirectional/polymorphic

ventricular ectopy

• VT/VF with physical activity

Arrhythmogenic Cardiomyopathy

• Fibro-fatty replacement of

myocardium

• Frequently seen with

ventricular ectopy

Premature Ventricular Contractions

CPVT

Arrhythmogenic Cardiomyopathy

When to order an EKG and/or echocardiogram as an adjunct to the preparticipation sports physical exam

Should a 12 lead EKG be incorporated within the preparticipation physical evaluation?

PPE, show me the data

Why No?

• False Positives

– Initial Italian study ~9%

• False Negatives

– Cardiomyopathy dynamic disease process

• No data it reduces risk

for SCD

• Logistics

Cost

• 10 million kids x $25= $250 million
• Add EKG $50 each = $750 million
• 15% false + rate= $2 billion per year program
• $3.4 million dollar cost to prevent SCD

False +

Real World Experience

Nevada HS 5,615 Sensitivity 70% vs 6% (EKG vs HP) North Carolina HS 2,017 H&P abnormal 14.7% compared to 3% EKG Chicago HS 32, 561 2.5% abnormal EKGs Texas Children's 2,506 Abnormal EKG 2.3% CHOP ~4,000 Abnormal EKG 2-3% (true + 0.7%)

Nicklaus Children’s Experience

211 224 2132 728 4426 4107 6667 8921 7600 1000 2000 3000 4000 5000 6000 7000 8000 9000 10000 2011 2012 2013 2014 2015 2016 2017 2018 2019

# of screenings

# of screenings

Final Thoughts

• Will EKG ever become apart of the PPE?
• Why only athletes and not all pediatric

patients?

• Does artificial intelligence help logistics and

cost?

In summary

• Ordering an EKG and/or echocardiogram as an

adjunct to the preparticipation sports physical exam

– Define Sudden Cardiac Arrest and etiologies – Discuses top 3 cardiac conditions leading to SCA – Should all pediatric patients undergo EKG screening in addition to the PPE?