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Precision Medicine: Science and Art. Jue Wang, MD, FACP Professor - PowerPoint PPT Presentation

Precision Medicine: Science and Art. Jue Wang, MD, FACP Professor of Medicine and Interdisciplinary Oncology The University of Arizona Cancer Center at Dignity Health St. Josephs Hospital and Medical Center Overview Traditional vs.


  1. Precision Medicine: Science and Art. Jue Wang, MD, FACP Professor of Medicine and Interdisciplinary Oncology The University of Arizona Cancer Center at Dignity Health St. Joseph’s Hospital and Medical Center

  2. Overview  Traditional vs. Precision Medicine: How They Differ  How Does Precision Medicine Work?  How Can Precision Medicine Help?  What Are the Benefits of Precision Medicine?

  3. Histological Diagnosis of Cancer Rudolph Ludwig Karl Virchow 1821- 1902

  4. Why the 'Best' Conventional Cancer Treatment Never Cure: "One size fits all"

  5. The American Way of Winning

  6. Clonal evolution in primary tumors and metastases

  7. Rapid emergence of compensatory mechanisms of resistance: Playing “Whack a Mole”

  8. Next-generation Sequencing of Advanced Prostate Cancer at UACC

  9. Advances in Understanding Cancer Genomes through Next-generation Sequencing Hallmarks of Cancer

  10. Cancer: Disorganized “Traffic Signal Systems”

  11. 63-year-old male with stage IV prostate cancer (diagnosed in 2013) Came to UACC second opinion clinic on 9/15/2015

  12. Achilles’ Heel for Prostate Cancer

  13. Harnessing Synthetic Lethal Interactions: Beating Cancer at Its Own Game BRCA2 (chr13:32582200)

  14. Harnessing Synthetic Lethal Interactions: Beating Cancer at Its Own Game

  15. Harnessing Synthetic Lethal Interactions: Beating Cancer at Its Own Game

  16. Harnessing Synthetic Lethal Interactions: Beating Cancer at Its Own Game

  17. Harness the Power of Precision Medicine to Target Prostate Cancer

  18. Thank You For more information about precision medicine or to request a speaker for your worksite or organization on any cancer-related topic Call: 602.699.3366

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