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Periorbital skin cancers
- High cosmeLc sensiLvity
- FuncLon and cosmesis of the area
- Simple dysfuncLonal problems can lead to
facial deformity
- Inadequate treatment would necessitate
PHOTODYNAMIC THERAPY IN THE MANAGEMENT OF PERIORBITAL SKIN CANCER - - PowerPoint PPT Presentation
PHOTODYNAMIC THERAPY IN THE MANAGEMENT OF PERIORBITAL SKIN CANCER - - PowerPoint PPT Presentation
PHOTODYNAMIC THERAPY IN THE MANAGEMENT OF PERIORBITAL SKIN CANCER Jerjes W, Hamdoon Z, Sultan A, Hopper C Periorbital skin cancers High cosmeLc sensiLvity FuncLon and cosmesis of the area Simple dysfuncLonal problems can lead to
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Periorbital skin tumours
- Benign or malignant
- BCC and SCC - most common ones
- Early diagnosis and intervenLon is essenLal
- The gold standard intervenLon - surgery
- Other intervenLons: radiotherapy,
chemotherapy, Mohs micrographic surgery, cryptherapy, topical intervenLons and photodynamic therapy
SLIDE 4
ProspecLve study
- 18 paLents with periorbital lesions
- These BCCs and thin SCCs were treated with
surface illuminaLon mTHPC-PDT
- Comparisons were made with the
clinicopathological parameters, anatomical locaLon, rate of recurrence and overall
- utcome.
- Follow-up - mean of 3.2 years
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Treatment parameters
- For the BCC lesions, IV 0.05mg/kg mTHPC
- DLI of 48hrs
- Micro-infiltraLon safety margin : 2mm
- For cutaneous SCC lesions, IV 0.1mg/kg
mTHPC
- DLI of 96hrs
- Micro-infiltraLon safety margin : 5mm.
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Results
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Results
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Results
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Conclusion
- PDT is a successful modality in the
management of these pathologies with an excellent cosmeLc outcome.
- PDT should be considered as an alternaLve
therapeuLc strategy for the adequate and cosmeLc treatment of lesions in these areas.
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