Oxford Clack Nutrition Study Dr Jonathan Tammam PhD RD RNutr - - PowerPoint PPT Presentation

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Oxford Clack Nutrition Study Dr Jonathan Tammam PhD RD RNutr - - PowerPoint PPT Presentation

Dec 17, 2022 450 likes •737 views

Oxford Clack Nutrition Study Dr Jonathan Tammam PhD RD RNutr Programme Lead and Principal Lecturer Nutrition and Dietetics, University of Hertfordshire Formerly: Research Scientist Physiology, Anatomy, and Genetics University of Oxford

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Oxford Clack Nutrition Study

Dr Jonathan Tammam PhD RD RNutr

Programme Lead and Principal Lecturer – Nutrition and Dietetics, University of Hertfordshire Formerly: Research Scientist – Physiology, Anatomy, and Genetics University of Oxford

j.tammam@herts.ac.uk

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Background – prisons

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Background – ADHD

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Background – schoolchildren

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Rationale

  • Consistent evidence in correctional facilities
  • Heterogeneous study design and results in

adolescents

  • Balance of evidence suggestive that multi-nutrient

approach needed

  • Nutrition surveys
  • lower SES poorer diets – micronutrient deficiencies
  • n3 from oily fish – low intakes
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Disadvantaged children have very low omega 3 levels (DOLAB trial)

Omega 3 level should be at least 8% Acknowledgement Prof J Stein

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Low n3/high n6 diet

Acknowledgement Prof J Stein

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Fish diet

  • Our brains could grow larger because
  • ur main food source was fish
  • In particular, fish supplied the omega-3,

Docosahexanoic acid (DHA) together with many vital vitamins and minerals

  • Our brains contain 5g of DHA because it

is an essential constituent of nerve membranes

  • Yet the average teenager eats no oily

fish and eats far too much omega 6 which competes for the same enzymes

Acknowledgement Prof J Stein

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Robert Clack School

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Demographics

  • 56% BME
  • 22% adult population unemployed
  • 34% children classified as living in poverty
  • 42% children from lone parent families
  • 40% children eligible for FSM
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Clinical trial – participant flow

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Clinical trial – supplements

Supplement contains

  • Vitamins
  • Minerals
  • Omega 3 fish oils
  • EPA
  • DHA

(Wellteen,Vitabiotics)

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Clinical trial – Conners scale

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Clinical trial – School records

  • Behaviour
  • Attitude
  • Fighting
  • Language
  • Underperformance
  • Uniform
  • Homework
  • Class work
  • Attendance
  • Punctuality
  • Rudeness
  • Late
  • Illness
  • Pastoral/Investigation
  • Truancy
  • Other
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BJN paper

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Results – nutrient status

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Results – nutrient status

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Results – behaviour (Conners)

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Results – behaviour (School records)

  • 60%
  • 40%
  • 20%

0% 20% 40% 60% All Low (<3) High (>3)

Misbehaviour

n=196 n=171 n=25

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Conclusions – nutritional status

  • Teenagers have low levels of n3 and several other

micronutrients

  • Pupils had very low baseline levels of EPA/DHA
  • Consistent with low intake of foods containing n3
  • Consistent with NDNS
  • n3 index improved but still <8%
  • All micronutrients measured were low baseline and

increased following supplementation.

  • Plasma concentrations of folate, vitamin C and vitamin

D increased significantly.

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Conclusions – behaviour

  • EPA, DHA, and other micronutrient status can be

improved upon supplementation.

  • Increasing levels may reduce misbehaviour
  • Recent study shows increased DHA associated with improved

parent-rated behaviour (Australia/ADHD)

  • Improved nutrition may translate to improved

behaviour in those with high misbehaviour rates

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Conclusions -behaviour

  • Supplements have protective effect against

worsening behaviour (Conners)

  • Potential large treatment effects in children with

high misbehaviour (School database)

  • Consistent with recent lab-based study measuring

impulsivity and aggression

  • Statistically significant but caution re small sub-sample
  • These findings should now be replicated in larger

studies

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Dietary intake – Eatwell

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Dietary intake – participants

Hagger, Stein, and Tammam (2016)

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Dietary intake – participants

Hagger, Stein, and Tammam (2016)

  • Fruit and Veg:
  • 1¼ per day (recommend 5 per day or 1/3 of diet)
  • 2% of participants consumed none
  • Dairy:
  • 70% of participants inadequate intake to meet Ca RNI
  • 5% of participants consumed no dairy
  • Oily fish:
  • 7.2g/wk (NDNS 11g/wk; recommend 140g/wk)
  • 39% participants consumed fish (tuna, f&c, fingers)
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Impact

  • Potential social implications
  • Public health policy
  • Need for improvement in adolescent nutritional

status by:

  • Supplementation
  • Dietary improvement
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Acknowledgements

  • Funders – Esmée Fairbairn, DRT, IFBB
  • Robert Clack School – Staff and students
  • Vitabiotics Ltd – Wellteen supplements
  • Blood analysis – University of Stirling and MRC HNR
  • Research Assistants