New Opportunities with PROMIS 1 LN Matheson, PhD EpicRehab The - - PowerPoint PPT Presentation
New Opportunities with PROMIS 1 LN Matheson, PhD EpicRehab The Promise of PROMIS 2 Patient Reported Outcome Measures Information System National Institutes of Health Develop and make available performance and self- report measures
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Patient Reported Outcome Measures Information System
National Institutes of Health
Develop and make available performance and self-
Available at no charge, with normative data that reflect
Item response theory was used to develop measures.
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What follows are culled from PowerPoint presentations
David Cella, PhD Nan Rothrock, PhD Shani Rolle, MS James Witter, MD, PhD
We thank them for their generosity and acknowledge
To continue NIH’s mission of successful medical research, it will
Requires the development of new partnerships of research with
industry, and academic researchers.
Need new paradigms in how clinical research information is collected,
used, and reported.
Includes the advances in information technology, psychometrics, and
qualitative, cognitive, and health survey research.
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Create a publicly available, adaptable and sustainable
Administer “tailored” questionnaires (using CAT technology)
Collect the patients’ responses for research and for
Provide instant health status reports to patients and health
Lay groundwork for public-private partnership to extend the
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Graduate Record Examination Graduate Management Admissions Test Uniform Certified Public Accountant Examination American Society of Clinical Pathologists -- Board of
Armed Services Vocational Aptitude Test Battery Missouri DMV Licensing Exam
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0.54 1.08 1.62 2.16 0.98 1.96 2.94 3.92 1.22 2.44 3.66 4.88 1.54 3.08 4.62 6.16 1.71 3.42 5.13 6.84 1 2 3 4 5 6 7 Unable Very Restricted Restricted Slightly Restricted Able
Response Categories Person Ability Level
Task A Task B Task C Task D Task E
This ability score (2.65) tells us what response to expect on each task.
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each question, stored in an “item bank” has been psychometrically and qualitatively reviewed as informative for measuring the health construct
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Select questions based on a person’s response to
Iteratively estimate a person’s standing on a domain
Administer most informative items Desired level if precision can be obtained using the
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Provide an accurate estimate of a person’s score
Minimize floor and ceiling effects
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1 2 3
Severe high moderate low very low
Emotional Distress
0.0 0.2 0.4 0.6 0.8 1.0
0.00 1.00 2.00 3.00
How often did you feel nervous?
All of the time Most of the time Little of the time Some of the time None of the time
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1 2 3
Severe high moderate low very low
Emotional Distress
0.0 0.2 0.4 0.6 0.8 1.0
0.00 1.00 2.00 3.00
How often did you feel nervous?
Some of the time
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1 2 3
Severe high moderate low very low
Emotional Distress
0.0 0.2 0.4 0.6 0.8 1.0
0.00 1.00 2.00 3.00
How often did you feel nervous?
Some of the time
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1 2 3
Severe high moderate low very low
Emotional Distress
0.0 0.2 0.4 0.6 0.8 1.0
0.00 1.00 2.00 3.00
How often did you feel hopeless?
All of the time Most of the time Little of the time Some of the time None of the time
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1 2 3
Severe high moderate low very low
Emotional Distress
0.0 0.2 0.4 0.6 0.8 1.0
0.00 1.00 2.00 3.00
How often did you feel hopeless?
Some of the time
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1 2 3
Severe high moderate low very low
Emotional Distress
0.0 0.2 0.4 0.6 0.8 1.0
0.00 1.00 2.00 3.00
How often did you feel worthless?
All of the time Most of the time Little of the time Some of the time None of the time
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1 2 3
Severe high moderate low very low
Emotional Distress
0.0 0.2 0.4 0.6 0.8 1.0
0.00 1.00 2.00 3.00
How often did you feel worthless?
Little of the time
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1 2 3
Severe high moderate low very low
0.0 0.2 0.4 0.6 0.8 1.0
0.00 1.00 2.00 3.00
How often did you feel worthless?
Little of the time
Target in on emotional distress score
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Quality of Life rather than Work IRT excellent for item development, but limited for CAT
Brevity (low response burden) emphasizes consistency
Clinicians make decisions based on incremental validity,
Try a PROMIS CAT:
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Female age 65 will live another 22.7 years Male age 65 will live another 20.5 years Chronic, non-catastrophic impairments accumulate >
Dressing Eating Ambulating Toileting Hygiene
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To be eligible for benefits, person must be unable to
Assistance with instrumental activities of daily living is
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