NeuroMat Parkinson Network (AMPARO) Andr Frazo Helene - - PowerPoint PPT Presentation

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NeuroMat Parkinson Network (AMPARO) Andr Frazo Helene - - PowerPoint PPT Presentation

NeuroMat Parkinson Network (AMPARO) Andr Frazo Helene https://amparo.numec.prp.usp.br/ Parkinson Parkinsons disease (PD) is a progressive neurodegenerative disorder with degeneration of nigrostriatal dopaminergic neurons in basal


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NeuroMat Parkinson Network (AMPARO)

André Frazão Helene

https://amparo.numec.prp.usp.br/

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Parkinson

  • Parkinson’s disease (PD) is a progressive

neurodegenerative disorder with degeneration of nigrostriatal dopaminergic neurons in basal ganglia (BG) resulting movement disorder characterized by

  • tremor
  • rigidity
  • Bradykinesia
  • postural instability
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Parkinson

  • Second most prevalent neurodegenerative

desease - between 80 and 160 cases per 100.000 inhabitants

  • In Brazil the burden of Parkinson disease is

expected to double over the next generation as the result of increasing life expectancy.

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Life expectancy – last 30 years

Year

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Dopaminergic cell loss

Substantia nigra pars compacta (SNc) GPi/SNr (globus pallidus internal e substantia nigra pars reticulata) globus pallidus external(GPe) Subthalamic nucleus (STN)

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Non motor symptons

  • In addition to the motor symptomatology some non-

motor symptoms involves:

– Hyposmia, rapid eye movements, sleep behaviour disorder, personality changes, pain, paresthesias and depression may be present and may even manifest before the motor symptoms – Urinary disturbances, orthostatic hypotension and neuropsychiatric disturbances (dementia, hallucinations and delirium) usually become evident and troublesome after several years in the course of the disease – Overt dementia is a late complication that most frequently patients with prolonged disease duration

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Progression

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Health promotion

World Health organization

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Comunity development

  • Successful health promotion demands a

coordinated action by governments, the health sector and other social and economic sectors, nongovernmental and voluntary

  • rganizations, local authorities, industry and

the media.

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NeuroMat Parkinson Network – AMPARO

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Partnership

  • Associação Brasil Parkinson

– The biggest association for PD in Brazil – ABP has more than 6.000 members living with PD – At least 10% of them have weekly activities in ABP – ABP offers structure for the evaluations involved in the project

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Comunity development

  • Meetings about parkinson desase – aiming
  • rganize people with parkinson desease on a

coordinated action that involves patients and community

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NeuroMat action on Parkinson - Amparo

  • Three main goals on
  • 1. Identify how people with Parkinson's disease

live

  • 2. What obstacles professionals find
  • 3. Contribute to change positively this reality
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Meetings

https://amparo.numec.prp.usp.br/

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Interventions an health education

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1 Parkinson’s Disease Progression Effects

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1 Parkinson’s Disease Progression Effects

Pavão e col. 2012

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2 Strategies on explicit guided actions

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Memory systems

Long Term Memory

Memory Systems

Long-term memory taxonomy, according to Squire and Zola-Morgan (1991).

Implicit Classic Condition

Priming Non-Associative Learning Emotional Responsas Skeletal Musculature Skills and Habits Explicit Facts Events

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3 EVALUATION OF IMPLICIT LEARNING

Pavão e col. 2016 – Scientific Reports

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EVALUATION OF IMPLICIT LEARNING

  • n pre-motor period
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Health promotion

World Health organization

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Health promotion

World Health organization

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Health promotion

World Health organization