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Mechanical Circulatory Support in Cardiogenic Shock What every cardiologist needs to know The Surgeon's view ACCA Masterclass 2017 R Trimlett (London, UK) Mechanical Circulatory Support in Cardiogenic Shock What every cardiologist needs


  1. Mechanical Circulatory Support in Cardiogenic Shock – What every cardiologist needs to know The Surgeon's view ACCA Masterclass 2017 R Trimlett (London, UK)

  2. Mechanical Circulatory Support in Cardiogenic Shock – What every cardiologist needs to know The Surgeon's view ACCA Masterclass 2017

  3. Potential for Cardiac Support TOTAL DIED Cath Lab 25,011 1,317 Cardiac Surgery 36,134 990 60000 Intensive Care 238,248 59,562 50000 40000 Accident & Emergency 18,142,311 20,358 30000 20000 Ambulance OOH Arrests 60,000 57,800 10000 0 ITU OOH A&E Cath lab Cardiac Arrest Surgery Overall UK Mortality 501,424 ACCA Masterclass 2017

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  8. Catheter Labs Mortality  25,011 Cases performed  1,317 died  5.3% mortality 81 Centres providing at least a working-hours Service. 22 performing less than 400 cases per year.

  9. Catheter Labs – OOHA followed by PCI = 1,083 ACCA Masterclass 2017

  10. IABP – SHOCK II Trial ACCA Masterclass 2017

  11. IABP – SHOCK II Trial ACCA Masterclass 2017

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  13. IMPELLA DEVICE Per-cutaneous / Surgical 2.5L / 5L+ Already anticoagulated. May cause Haemolysis. ACCA Masterclass 2017

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  21. Compact CardioHelp VV / VA Portable Device ACCA Masterclass 2017

  22. External Artificial Heart and Lungs Uses of VA-ECMO • Cardiogenic shock • Large myocardial infarction (MI) • Assistance with CPR using (E-CPR) • Post-cardiotomy shock • Bridge to more definitive treatment, • Bridge to left ventricular assist device (LVAD) • Bridge to decision • Cardiomyopathic process • Fulminant myocarditis • Sepsis-associated cardiomyopathy • Pulmonary hypertension • Pulmonary embolism with right heart failure • Class IV/stage D heart failure • Post heart transplantation ACCA Masterclass 2017

  23. CONSIDERATIONS FOR V-A ECMO CANNULATION  Time / Urgency  Facilities / Location  Anatomical Considerations / Physical Size  Previous or planned Surgery / Vascular Access ACCA Masterclass 2017

  24. CONSIDERATIONS FOR V-A ECMO CANNULATION ARTERIAL ACCESS Single Cannula or Multiple Cannulae Femoral Subclavian Aorta Left Ventricle Carotid ACCA Masterclass 2017

  25. BODY SURFACE AREA – RULE OF NINES ACCA Masterclass 2017

  26. PRESSURE OF TIME – TWO QUICKEST STRATEGIES (I) 1. FEMORAL CANNULATION Ultrasound Bilateral approach Percutaneous vs. Open Sterile Field Small Cannulae ACCA Masterclass 2017

  27. PRESSURE OF TIME – TWO QUICKEST STRATEGIES (II) 2. EMERGENCY STERNOTOMY You will need a saw. If you have a saw, this is very quick Bleeding Sterility Transport ACCA Masterclass 2017

  28. PRESSURE OF TIME – TWO QUICKEST STRATEGIES (II) Sternotomy and ‘Clam shell’ incisions both give good emergency access to Heart and Great Vessels. Clam shell can be done Without a saw. Need two retractors for Best access. ACCA Masterclass 2017

  29. FEMORAL CANNULATION X-Ray Guided Approach 0.035” J -wire provided (soft) Amplatz Super Stiff if prev. femoral op. Dilate properly and incise skin Wire can loop down opposite leg Wire can enter Hepatic or renal veins ACCA Masterclass 2017

  30. FEMORAL VENOUS CANNULATION CANNULA CHOICE Size Multi-stage Dual Drainage / Ascites Cannula Positioning ACCA Masterclass 2017

  31. FEMORAL ARTERIAL CANNULATION CANNULA CHOICE Size Distal Perfusion Side arm vent Wire re-inforced ACCA Masterclass 2017

  32. ALTERNATIVE FEMORAL ARTERIAL CANNULATION Division of Inguinal Ligament 10mm Side Graft to External Iliac A. No Cannula Used No Distal Perfusion Issues Simple Decannulation ACCA Masterclass 2017

  33. ALTERNATIVE FEMORAL ARTERIAL CANNULATION Conventional with Cannulae Surgical Side Graft 10mm Gelseal ACCA Masterclass 2017

  34. Technique for Cannulation 10mm Graft 3/8” – 3/8” connector 3/8” = 9.56325mm

  35. CONSIDERATIONS FOR V-A ECMO CANNULATION – FACILITIES Accident and Emergency Resus. Hybrid Theatre Suite ACCA Masterclass 2017

  36. ALTERNATIVE FEMORAL ARTERIAL CANNULATION ACCA Masterclass 2017

  37. STANDARD CANNULATION SITES IN OPEN CHEST ACCA Masterclass 2017

  38. OPEN-CHEST SITUATIONS In an Emergency pipes can be held in place. Minimizes retrograde Aortic flow. ACCA Masterclass 2017

  39. OPEN-CHEST SITUATIONS Often, in complex Aortic cases, the whole Aortic is replaced by a woven Dacron tube. Haemostasis is a major challenge. Kinking of grafts is an issue. ACCA Masterclass 2017

  40. Aortic Pulse Amplification As mean pressure falls along the aorta, the pressure wave is delayed and the pulse amplitude raised. ACCA Masterclass 2017

  41. Aortic Compliance ACCA Masterclass 2017

  42. THE IMPORTANCE OF LOW SHEAR STRESSES Haemolysis ? CVA Lower Pump RPM Less ‘Jet Wash’ of Aorta ACCA Masterclass 2017

  43. AVOIDING FLOW-LIMITING CANNULAE WITH GELSEAL GRAFTS No need to remove when weaning off ECMO Close with Stapler and leave a small stump. ACCA Masterclass 2017

  44. VA-ECMO IN THE PRESENCE OF AORTIC REGURGITATION Relative Contraindication Ignore. Balloon Pump. LV Vent. Change Valve (AVR). TAVI. Impella Device. ACCA Masterclass 2017

  45. IMPELLA DEVICE ACCA Masterclass 2017

  46. Rapid Expansion in Cardiac ECMO (UK) ACCA Masterclass 2017

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  48. A Systematic Research and Meta-analysis patients with a diagnosis of ACS treated with extracorporeal circulatory support 913 Patients, short term mortality 62% 347 Patients, 6-month mortality 24% 264 Patients, 1-year mortality 17% 219 Patients alive at 1 year = 76% mortality ACCA Masterclass 2017

  49. Journal of Cardiac Failure Vol. 20 No. 8S August 2014, Sandeep M. Jani et al. Acute Cardiac Diagnoses. Post-cardiotomy. Acute Decompensation of ACS Chronic Heart Failure. “Other” ACCA Masterclass 2017

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  54. 3 Months 3 years, 1 month ACCA Masterclass 2017

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